ENSG00000258677 Gene (Protein Coding)

 

GC08M073688
GIFtS:
7
See more...

Aliases for ENSG00000258677 Gene

Aliases for ENSG00000258677 Gene

  • UBIQUITIN_CONJUGAT_2 Domain-Containing Protein 13
  • Novel Protein, UBE2W-STAU2 Readthrough 5
  • AC022826.2 5

External Ids for ENSG00000258677 Gene

Previous GeneCards Identifiers for ENSG00000258677 Gene

  • GC08M074600

Summaries for ENSG00000258677 Gene

GeneCards Summary for ENSG00000258677 Gene

ENSG00000258677 is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include ubiquitin protein ligase binding and acid-amino acid ligase activity. An important paralog of this gene is UBE2W.

Additional gene information for ENSG00000258677 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ENSG00000258677 Gene

Genomics for ENSG00000258677 Gene

GeneHancer (GH) Regulatory Elements Pubs

Download GeneHancer 2017 data
Promoters and enhancers for ENSG00000258677 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH08J073876 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 600.7 +0.4 353 4.2 SP1 HNRNPL CREB1 GATAD2A ATF7 PRDM10 REST ZNF629 ZNF512 RFX1 UBE2W ENSG00000258677 ENSG00000286113 LINC01617 ELOC TMEM70 piR-54764-614 STAU2
GH08J073867 Enhancer 0.6 ENCODE 0.4 +10.3 10343 1.4 PKNOX1 IKZF2 TRIM22 ARID3A RELB CEBPB RUNX3 CBFB USF1 BCL11A STAU2 UBE2W ENSG00000258677 piR-54764-614
GH08J073745 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 0.1 +132.3 132253 4 CTCF ZBTB33 PRDM10 LEF1 KDM1A ZNF692 POLR2A BACH1 TARDBP LARP7 STAU2 lnc-UBE2W-1 RDH10 RF00017-7131 ENSG00000258677 RPL7
GH08J073792 Promoter/Enhancer 1.4 UCNEbase EPDnew Ensembl ENCODE 0.2 +85.1 85053 2 NR2C1 CEBPB NR2C2 MAX NR2F2 CEBPG NR2F1 NR2F6 JUN UBE2W STAU2 lnc-STAU2-3 piR-33905-087 ENSG00000258677
GH08J073858 Enhancer 0.5 Ensembl 0.4 +18.6 18553 3.8 PRDM10 ZSCAN4 RUNX3 BCLAF1 PRDM6 ATF7 SPI1 ZBTB33 STAU2 TMEM70 ELOC UBE2W piR-54764-614 ENSG00000258677
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ENSG00000258677 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for ENSG00000258677 Gene

Genomic Locations for ENSG00000258677 Gene
chr8:73,688,691-73,878,854
(GRCh38/hg38)
Size:
190,164 bases
Orientation:
Minus strand
chr8:74,600,926-74,791,089
(GRCh37/hg19)
Size:
190,164 bases
Orientation:
Minus strand

Genomic View for ENSG00000258677 Gene

Genes around ENSG00000258677 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ENSG00000258677 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ENSG00000258677 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

No data available for RefSeq DNA sequence for ENSG00000258677 Gene

Proteins for ENSG00000258677 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

  • Protein details for ENSG00000258677 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    H3BMM0-H3BMM0_HUMAN
    Recommended name:
    UBIQUITIN_CONJUGAT_2 domain-containing protein
    Protein Accession:
    H3BMM0

    Protein attributes for ENSG00000258677 Gene

    Size:
    161 amino acids
    Molecular mass:
    18562 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ENSG00000258677 Gene

Post-translational modifications for ENSG00000258677 Gene

No Post-translational modifications

Other Protein References for ENSG00000258677 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for ENSG00000258677 Gene

Domains & Families for ENSG00000258677 Gene

Protein Domains for ENSG00000258677 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with ENSG00000258677: view

No data available for Gene Families , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for ENSG00000258677 Gene

Function for ENSG00000258677 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Phenotypes From GWAS Catalog for ENSG00000258677 Gene

Gene Ontology (GO) - Molecular Function for ENSG00000258677 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0061631 ubiquitin conjugating enzyme activity IBA --
genes like me logo Genes that share ontologies with ENSG00000258677: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ENSG00000258677 Gene

Localization for ENSG00000258677 Gene

Gene Ontology (GO) - Cellular Components for ENSG00000258677 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA --
genes like me logo Genes that share ontologies with ENSG00000258677: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for ENSG00000258677 Gene

Pathways & Interactions for ENSG00000258677 Gene

PathCards logo

SuperPathways for ENSG00000258677 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ENSG00000258677 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000209 protein polyubiquitination IBA --
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IBA --
genes like me logo Genes that share ontologies with ENSG00000258677: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for ENSG00000258677 Gene

Drugs & Compounds for ENSG00000258677 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for ENSG00000258677 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for ENSG00000258677 Gene

1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for ENSG00000258677 Gene

No ASD Table

Relevant External Links for ENSG00000258677 Gene

GeneLoc Exon Structure for
ENSG00000258677

Expression for ENSG00000258677 Gene

Products:

  1. Primer

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ENSG00000258677 Gene

mRNA expression in normal human tissues for ENSG00000258677 Gene
genes like me logo Genes that share expression patterns with ENSG00000258677: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ENSG00000258677 Gene

Orthologs for ENSG00000258677 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ENSG00000258677 Gene

Organism Taxonomy Gene Similarity Type Details
Oppossum
(Monodelphis domestica)
 Mammalia -- 31
  • 97 (a)
 OneToMany
Cow
(Bos Taurus)
 Mammalia UBE2W 31
  • 97 (a)
 OneToMany
Platypus
(Ornithorhynchus anatinus)
 Mammalia -- 31
  • 95 (a)
 OneToMany
Dog
(Canis familiaris)
 Mammalia -- 31
  • 82 (a)
 OneToMany
Chicken
(Gallus gallus)
 Aves UBE2W 31
  • 97 (a)
 OneToMany
Zebrafish
(Danio rerio)
 Actinopterygii flj11011l 31
  • 91 (a)
 ManyToMany
ube2w 31
  • 91 (a)
 ManyToMany
Fruit Fly
(Drosophila melanogaster)
 Insecta CG7220 31
  • 55 (a)
 OneToMany
Worm
(Caenorhabditis elegans)
 Secernentea ubc-16 31
  • 57 (a)
 OneToMany
Baker's yeast
(Saccharomyces cerevisiae)
 Saccharomycetes UBC11 31
  • 29 (a)
 OneToMany
Species where no ortholog for ENSG00000258677 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)

Evolution for ENSG00000258677 Gene

ENSEMBL:
Gene Tree for ENSG00000258677 (if available)
TreeFam:
Gene Tree for ENSG00000258677 (if available)

Paralogs for ENSG00000258677 Gene

Paralogs for ENSG00000258677 Gene

genes like me logo Genes that share paralogs with ENSG00000258677: view

Variants for ENSG00000258677 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Additional dbSNP identifiers (rs#s) , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Additional Variant Information for ENSG00000258677 Gene

Disorders for ENSG00000258677 Gene

No disorders were found for ENSG00000258677 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for ENSG00000258677 Gene

Publications for ENSG00000258677 Gene

  1. DNA sequence and analysis of human chromosome 8. (PMID: 16421571) Nusbaum C … Lander ES (Nature 2006) 13

No data available for Mastermind for ENSG00000258677 Gene

Products for ENSG00000258677 Gene

Sources for ENSG00000258677 Gene