ENSG00000258674 Gene (Protein Coding)

 

GC19P019516
GIFtS:
9

Aliases for ENSG00000258674 Gene

Aliases for ENSG00000258674 Gene

  • YjeF N-Terminal Domain-Containing Protein 13
  • Novel Protein 5
  • AC011448.1 5

External Ids for ENSG00000258674 Gene

Previous GeneCards Identifiers for ENSG00000258674 Gene

  • GC19P019628
  • GC19P019629

Summaries for ENSG00000258674 Gene

GeneCards Summary for ENSG00000258674 Gene

ENSG00000258674 is a Protein Coding gene. An important paralog of this gene is YJEFN3.

Additional gene information for ENSG00000258674 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ENSG00000258674 Gene

Genomics for ENSG00000258674 Gene

GeneHancer (GH) Regulatory Elements for ENSG00000258674 Gene

Promoters and enhancers for ENSG00000258674 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH19J019515 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 750.6 +0.2 174 2.4 E2F8 ZBTB40 SIX5 SMARCE1 POLR2A ATF1 CREB1 HCFC1 MIXL1 MYC NDUFA13 ENSG00000258674 NONHSAG025185.2 TSSK6 piR-56535 ENSG00000268030 NR2C2AP MAU2 ZNF90 UPF1
GH19J019516 Promoter/Enhancer 1 Ensembl ENCODE CraniofacialAtlas 750.6 -1.8 -1830 0.8 MAX ZBTB33 ENSG00000258674 NONHSAG025185.2 NDUFA13 TSSK6 piR-56535 GATAD2A lnc-TSSK6-2
GH19J019517 Enhancer 0.3 ENCODE 750.6 -1.3 -1317 0.1 MLLT1 ZBTB33 ENSG00000258674 NONHSAG025185.2 NDUFA13 TSSK6 piR-56535 lnc-TSSK6-2
GH19J019529 Promoter/Enhancer 1.2 EPDnew Ensembl ENCODE CraniofacialAtlas 0.4 +13.7 13673 3.4 ZBTB6 POLR2A SP1 RFX1 EGR1 ZNF623 BCOR ZFHX2 SUPT5H CEBPB YJEFN3 NDUFA13 GATAD2A PBX4 LPAR2 GMIP ATP13A1 lnc-TSSK6-3 ENSG00000258674
GH19J019532 Enhancer 1 Ensembl ENCODE 0.4 +16.9 16873 2.2 CTCF MYC CC2D1A L3MBTL2 RAD21 ARID2 REST TRIM22 ATF1 ZNF143 NDUFA13 GATAD2A ZNF506 ZNF14 YJEFN3 lnc-TSSK6-3 ENSG00000258674
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ENSG00000258674 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ENSG00000258674 Gene

Genomic Locations for ENSG00000258674 Gene
chr19:19,516,227-19,536,076
(GRCh38/hg38)
Size:
19,850 bases
Orientation:
Plus strand
chr19:19,627,036-19,646,885
(GRCh37/hg19)
Size:
19,850 bases
Orientation:
Plus strand

Genomic View for ENSG00000258674 Gene

Genes around ENSG00000258674 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ENSG00000258674 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ENSG00000258674 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

No data available for RefSeq DNA sequence for ENSG00000258674 Gene

Proteins for ENSG00000258674 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

  • Protein details for ENSG00000258674 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    E7ENQ6-E7ENQ6_HUMAN
    Recommended name:
    YjeF N-terminal domain-containing protein
    Protein Accession:
    E7ENQ6

    Protein attributes for ENSG00000258674 Gene

    Size:
    273 amino acids
    Molecular mass:
    30095 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ENSG00000258674 Gene

Protein Expression for ENSG00000258674 Gene

See protein expression from ProteomicsDB, MOPED, PaxDb, and MaxQB

Post-translational modifications for ENSG00000258674 Gene

No Post-translational modifications

Other Protein References for ENSG00000258674 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for ENSG00000258674 Gene

Domains & Families for ENSG00000258674 Gene

Protein Domains for ENSG00000258674 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with ENSG00000258674: view

No data available for Gene Families , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for ENSG00000258674 Gene

Function for ENSG00000258674 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Phenotypes From GWAS Catalog for ENSG00000258674 Gene

Gene Ontology (GO) - Molecular Function for ENSG00000258674 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0052856 NADHX epimerase activity IBA --
GO:0052857 NADPHX epimerase activity IBA --
genes like me logo Genes that share ontologies with ENSG00000258674: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ENSG00000258674 Gene

Localization for ENSG00000258674 Gene

Gene Ontology (GO) - Cellular Components for ENSG00000258674 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with ENSG00000258674: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for ENSG00000258674 Gene

Pathways & Interactions for ENSG00000258674 Gene

PathCards logo

SuperPathways for ENSG00000258674 Gene

No Data Available

Interacting Proteins for ENSG00000258674 Gene

STRING Interaction Network Preview (showing top 5 STRING interactants - click image to see top 25)
STRING Interaction Network
Selected Interacting proteins: ENSP00000452549 for ENSG00000258674 Gene via STRING

Gene Ontology (GO) - Biological Process for ENSG00000258674 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ENSG00000258674 Gene

Drugs & Compounds for ENSG00000258674 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for ENSG00000258674 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for ENSG00000258674 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for ENSG00000258674 Gene

No ASD Table

Relevant External Links for ENSG00000258674 Gene

GeneLoc Exon Structure for
ENSG00000258674

Expression for ENSG00000258674 Gene

Products:

  1. Primer

Integrated Proteomics: protein expression in normal tissues and cell lines from MaxQB and MOPED for ENSG00000258674 Gene



No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ENSG00000258674 Gene

Orthologs for ENSG00000258674 Gene

This gene was present in the common ancestor of animals.

Orthologs for ENSG00000258674 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
 Mammalia -- 33
  • 72 (a)
 OneToOne
oppossum
(Monodelphis domestica)
 Mammalia -- 33
  • 68 (a)
 OneToMany
cow
(Bos Taurus)
 Mammalia NDUFA13 33
  • 66 (a)
 OneToOne
platypus
(Ornithorhynchus anatinus)
 Mammalia -- 33
  • 61 (a)
 OneToMany
chicken
(Gallus gallus)
 Aves -- 33
  • 40 (a)
 OneToMany
fruit fly
(Drosophila melanogaster)
 Insecta CG3446 33
  • 26 (a)
 OneToMany
worm
(Caenorhabditis elegans)
 Secernentea C34B2.8 33
  • 22 (a)
 OneToMany
Species where no ortholog for ENSG00000258674 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

Evolution for ENSG00000258674 Gene

ENSEMBL:
Gene Tree for ENSG00000258674 (if available)
TreeFam:
Gene Tree for ENSG00000258674 (if available)

Paralogs for ENSG00000258674 Gene

Paralogs for ENSG00000258674 Gene

genes like me logo Genes that share paralogs with ENSG00000258674: view

Variants for ENSG00000258674 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Additional Variant Information for ENSG00000258674 Gene

Disorders for ENSG00000258674 Gene

No disorders were found for ENSG00000258674 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for ENSG00000258674 Gene

Publications for ENSG00000258674 Gene

  1. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 13 56

No data available for External Links for ENSG00000258674 Gene

Products for ENSG00000258674 Gene

Sources for ENSG00000258674 Gene