Aliases for ENSG00000258539 Gene

Aliases for ENSG00000258539 Gene

  • Novel Transcript, METTL10-FAM53B Readthrough 5
  • Methyltranfer_dom Domain-Containing Protein 13
  • AC068896.1 5

External Ids for ENSG00000258539 Gene

Previous GeneCards Identifiers for ENSG00000258539 Gene

  • GC10M126305

Summaries for ENSG00000258539 Gene

GeneCards Summary for ENSG00000258539 Gene

ENSG00000258539 is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include methyltransferase activity and tRNA (guanine-N7-)-methyltransferase activity. An important paralog of this gene is EEF1AKMT2.

Additional gene information for ENSG00000258539 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ENSG00000258539 Gene

Genomics for ENSG00000258539 Gene

GeneHancer (GH) Regulatory Elements for ENSG00000258539 Gene

Promoters and enhancers for ENSG00000258539 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ENSG00000258539 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ENSG00000258539 Gene

Genomic Locations for ENSG00000258539 Gene
chr10:124,617,080-124,791,727
(GRCh38/hg38)
Size:
174,648 bases
Orientation:
Minus strand
chr10:126,305,649-126,480,296
(GRCh37/hg19)
Size:
174,648 bases
Orientation:
Minus strand

Genomic View for ENSG00000258539 Gene

Genes around ENSG00000258539 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ENSG00000258539 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ENSG00000258539 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for RefSeq DNA sequence for ENSG00000258539 Gene

Proteins for ENSG00000258539 Gene

  • Protein details for ENSG00000258539 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    H3BQF6-H3BQF6_HUMAN
    Recommended name:
    Methyltranfer_dom domain-containing protein
    Protein Accession:
    H3BQF6

    Protein attributes for ENSG00000258539 Gene

    Size:
    201 amino acids
    Molecular mass:
    22711 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ENSG00000258539 Gene

Post-translational modifications for ENSG00000258539 Gene

No Post-translational modifications

Other Protein References for ENSG00000258539 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for ENSG00000258539 Gene

Domains & Families for ENSG00000258539 Gene

Protein Domains for ENSG00000258539 Gene

genes like me logo Genes that share domains with ENSG00000258539: view

No data available for Gene Families , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for ENSG00000258539 Gene

Function for ENSG00000258539 Gene

Phenotypes From GWAS Catalog for ENSG00000258539 Gene

Gene Ontology (GO) - Molecular Function for ENSG00000258539 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008168 methyltransferase activity IEA --
GO:0016279 protein-lysine N-methyltransferase activity IBA --
genes like me logo Genes that share ontologies with ENSG00000258539: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ENSG00000258539 Gene

Localization for ENSG00000258539 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for ENSG00000258539 Gene

Pathways & Interactions for ENSG00000258539 Gene

PathCards logo

SuperPathways for ENSG00000258539 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for ENSG00000258539 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0018026 peptidyl-lysine monomethylation IBA --
GO:0018027 peptidyl-lysine dimethylation IBA --
genes like me logo Genes that share ontologies with ENSG00000258539: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for ENSG00000258539 Gene

Drugs & Compounds for ENSG00000258539 Gene

No Compound Related Data Available

Transcripts for ENSG00000258539 Gene

mRNA/cDNA for ENSG00000258539 Gene

1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for ENSG00000258539 Gene

No ASD Table

Relevant External Links for ENSG00000258539 Gene

GeneLoc Exon Structure for
ENSG00000258539

Expression for ENSG00000258539 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ENSG00000258539 Gene

mRNA expression in normal human tissues for ENSG00000258539 Gene
genes like me logo Genes that share expression patterns with ENSG00000258539: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ENSG00000258539 Gene

Orthologs for ENSG00000258539 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ENSG00000258539 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia -- 31
  • 93 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mettl10 31
  • 73 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 31
  • 72 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 31
  • 70 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii mettl10 31
  • 52 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG9643 31
  • 42 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea F29B9.1 31
  • 32 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes SEE1 31
  • 28 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 31
  • 38 (a)
OneToMany
Species where no ortholog for ENSG00000258539 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ENSG00000258539 Gene

ENSEMBL:
Gene Tree for ENSG00000258539 (if available)
TreeFam:
Gene Tree for ENSG00000258539 (if available)

Paralogs for ENSG00000258539 Gene

Paralogs for ENSG00000258539 Gene

genes like me logo Genes that share paralogs with ENSG00000258539: view

Variants for ENSG00000258539 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Additional dbSNP identifiers (rs#s) , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Additional Variant Information for ENSG00000258539 Gene

Disorders for ENSG00000258539 Gene

No disorders were found for ENSG00000258539 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for ENSG00000258539 Gene

Publications for ENSG00000258539 Gene

  1. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P … Rogers J (Nature 2004) 13 54

No data available for Mastermind for ENSG00000258539 Gene

Products for ENSG00000258539 Gene

Sources for ENSG00000258539 Gene