Aliases for ENSG00000257767 Gene

Aliases for ENSG00000257767 Gene

  • Aldedh Domain-Containing Protein 13
  • Novel Protein 5
  • AC002996.1 5

External Ids for ENSG00000257767 Gene

Previous GeneCards Identifiers for ENSG00000257767 Gene

  • GC12P112193

Summaries for ENSG00000257767 Gene

GeneCards Summary for ENSG00000257767 Gene

ENSG00000257767 is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity. An important paralog of this gene is ALDH2.

Additional gene information for ENSG00000257767 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ENSG00000257767 Gene

Genomics for ENSG00000257767 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for ENSG00000257767 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12J111753 Enhancer 1 ENCODE dbSUPER 600.7 -0.5 -488 0.2 CTCF IKZF1 JUND LARP7 ZNF143 REST RAD21 IRF2 ZBED1 ZNF444 ENSG00000257767 ALDH2 MAPKAPK5 MAPKAPK5-AS1 HSALNG0094056 ACAD10
GH12J111754 Enhancer 0.3 ENCODE dbSUPER 600.7 +1.0 1002 0.2 ENSG00000257767 lnc-ACAD10-2 ALDH2 ACAD10
GH12J111755 Enhancer 0.2 Ensembl 600.7 +1.8 1811 0.2 ENSG00000257767 lnc-ACAD10-2 ALDH2 ACAD10
GH12J111766 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 0.4 +13.6 13582 3.3 ZBTB33 PRDM10 IKZF1 NFKBIZ ZNF692 RCOR2 JUND MTA2 ZIC2 RBFOX2 ALDH2 ATXN2 ADAM1A HECTD4 ENSG00000257767 MIR6761 MAPKAPK5
GH12J111772 Enhancer 1.5 FANTOM5 ENCODE CraniofacialAtlas dbSUPER 0.4 +21.9 21854 6.2 SP1 GATAD2A PRDM10 REST TFE3 LEF1 IKZF1 NFKBIZ POLR2A BACH1 ALDH2 ACAD10 BRAP SH2B3 PHETA1 ENSG00000257767 MIR6761 MAPKAPK5
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ENSG00000257767 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for ENSG00000257767 Gene

Genomic Locations for ENSG00000257767 Gene
chr12:111,753,890-111,791,418
(GRCh38/hg38)
Size:
37,529 bases
Orientation:
Plus strand
chr12:112,191,694-112,229,222
(GRCh37/hg19)
Size:
37,529 bases
Orientation:
Plus strand

Genomic View for ENSG00000257767 Gene

Genes around ENSG00000257767 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ENSG00000257767 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ENSG00000257767 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for RefSeq DNA sequence for ENSG00000257767 Gene

Proteins for ENSG00000257767 Gene

  • Protein details for ENSG00000257767 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    F8VP50-F8VP50_HUMAN
    Recommended name:
    Aldedh domain-containing protein
    Protein Accession:
    F8VP50

    Protein attributes for ENSG00000257767 Gene

    Size:
    261 amino acids
    Molecular mass:
    28484 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ENSG00000257767 Gene

Post-translational modifications for ENSG00000257767 Gene

No Post-translational modifications

Other Protein References for ENSG00000257767 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for ENSG00000257767 Gene

Domains & Families for ENSG00000257767 Gene

Gene Families for ENSG00000257767 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ENSG00000257767 Gene

genes like me logo Genes that share domains with ENSG00000257767: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for ENSG00000257767 Gene

Function for ENSG00000257767 Gene

Phenotypes From GWAS Catalog for ENSG00000257767 Gene

Gene Ontology (GO) - Molecular Function for ENSG00000257767 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004029 aldehyde dehydrogenase (NAD) activity IBA --
GO:0016491 oxidoreductase activity IEA --
genes like me logo Genes that share ontologies with ENSG00000257767: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ENSG00000257767 Gene

Localization for ENSG00000257767 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for ENSG00000257767 Gene

Pathways & Interactions for ENSG00000257767 Gene

PathCards logo

SuperPathways for ENSG00000257767 Gene

No Data Available

Interacting Proteins for ENSG00000257767 Gene

STRING Interaction Network Preview (showing top 5 STRING interactants - click image to see top 25)
STRING Interaction Network
Selected Interacting proteins: ENSP00000450353 for ENSG00000257767 Gene via STRING

Gene Ontology (GO) - Biological Process for ENSG00000257767 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0055114 oxidation-reduction process IEA --
genes like me logo Genes that share ontologies with ENSG00000257767: view

No data available for Pathways by source and SIGNOR curated interactions for ENSG00000257767 Gene

Drugs & Compounds for ENSG00000257767 Gene

No Compound Related Data Available

Transcripts for ENSG00000257767 Gene

mRNA/cDNA for ENSG00000257767 Gene

1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for ENSG00000257767 Gene

No ASD Table

Relevant External Links for ENSG00000257767 Gene

GeneLoc Exon Structure for
ENSG00000257767

Expression for ENSG00000257767 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ENSG00000257767 Gene

mRNA expression in normal human tissues for ENSG00000257767 Gene
genes like me logo Genes that share expression patterns with ENSG00000257767: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ENSG00000257767 Gene

Orthologs for ENSG00000257767 Gene

This gene was present in the common ancestor of animals.

Orthologs for ENSG00000257767 Gene

Organism Taxonomy Gene Similarity Type Details
Mouse
(Mus musculus)
Mammalia Aldh2 31
  • 44 (a)
OneToMany
Dog
(Canis familiaris)
Mammalia -- 31
  • 43 (a)
ManyToMany
-- 31
  • 36 (a)
ManyToMany
Cow
(Bos Taurus)
Mammalia ALDH2 31
  • 42 (a)
OneToMany
Chimpanzee
(Pan troglodytes)
Mammalia ALDH2 31
  • 41 (a)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia -- 31
  • 40 (a)
OneToMany
Oppossum
(Monodelphis domestica)
Mammalia -- 31
  • 38 (a)
OneToMany
Chicken
(Gallus gallus)
Aves -- 31
  • 40 (a)
OneToMany
Lizard
(Anolis carolinensis)
Reptilia -- 31
  • 38 (a)
OneToMany
Zebrafish
(Danio rerio)
Actinopterygii CABZ01032488.1 31
  • 4 (a)
ManyToMany
Fruit Fly
(Drosophila melanogaster)
Insecta Aldh 31
  • 33 (a)
OneToMany
Species where no ortholog for ENSG00000257767 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for ENSG00000257767 Gene

ENSEMBL:
Gene Tree for ENSG00000257767 (if available)
TreeFam:
Gene Tree for ENSG00000257767 (if available)

Paralogs for ENSG00000257767 Gene

genes like me logo Genes that share paralogs with ENSG00000257767: view

Variants for ENSG00000257767 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Additional dbSNP identifiers (rs#s) , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Additional Variant Information for ENSG00000257767 Gene

Disorders for ENSG00000257767 Gene

Additional Disease Information for ENSG00000257767

No disorders were found for ENSG00000257767 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ENSG00000257767 Gene

Publications for ENSG00000257767 Gene

  1. The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer SE … Baylor College of Medicine Human Genome Sequencing Center Sequence Production Team (Nature 2006) 13

No data available for Mastermind for ENSG00000257767 Gene

Products for ENSG00000257767 Gene

Sources for ENSG00000257767 Gene