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Aliases for ENSG00000256206 Gene

Aliases for ENSG00000256206 Gene

  • Proteasome Subunit Alpha Type 13
  • Novel Transcript 5
  • EC 3.4.25.1 4
  • AC018523.2 5

External Ids for ENSG00000256206 Gene

Summaries for ENSG00000256206 Gene

GeneCards Summary for ENSG00000256206 Gene

ENSG00000256206 is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include endopeptidase activity and threonine-type endopeptidase activity. An important paralog of this gene is PSMA1.

Additional gene information for ENSG00000256206 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ENSG00000256206 Gene

Genomics for ENSG00000256206 Gene

GeneHancer (GH) Regulatory Elements for ENSG00000256206 Gene

Promoters and enhancers for ENSG00000256206 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J014518 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 600.7 +0.4 408 3 ZNF652 CC2D1A SP1 ZFX ELF3 SIX5 ZNF148 NKRF POLR2A MLLT1 ENSG00000256206 PSMA1 COPB1 SPON1 RRAS2
GH11J014498 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 0.3 +20.4 20411 3.5 MTA3 ZNF652 SP1 ZFX ELF3 ZNF148 NKRF POLR2A MLLT1 CEBPG COPB1 RNU7-49P ENSG00000256206
GH11J014536 Enhancer 0.9 FANTOM5 ENCODE 0.4 -17.1 -17089 1.2 CTCF ZNF384 RAD21 SMARCA4 GMEB1 TRIM22 NR2C1 SOX6 SMC3 NR2F2 PSMA1 PDE3B COPB1 ENSG00000256206 PIR39085
GH11J014577 Enhancer 1.2 FANTOM5 ENCODE 0.2 -58.8 -58836 3.7 ELF3 CEBPG TRIM24 SP1 PPARG CREM KAT8 RXRA IKZF2 CEBPA PDE3B PSMA1 CYP2R1 PIR39085 ENSG00000256206
GH11J014544 Enhancer 0.8 ENCODE 0.3 -24.4 -24386 0.2 BACH1 MAFK TRIM24 SP1 CREM SMARCA4 ZBED1 IKZF1 IKZF2 NFE2L2 PDE3B PSMA1 ENSG00000256206 PIR39085
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ENSG00000256206 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ENSG00000256206 Gene

Genomic Locations for ENSG00000256206 Gene
chr11:14,493,783-14,520,344
(GRCh38/hg38)
Size:
26,562 bases
Orientation:
Minus strand
chr11:14,515,329-14,541,890
(GRCh37/hg19)
Size:
26,562 bases
Orientation:
Minus strand

Genomic View for ENSG00000256206 Gene

Genes around ENSG00000256206 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ENSG00000256206 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ENSG00000256206 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for RefSeq DNA sequence for ENSG00000256206 Gene

Proteins for ENSG00000256206 Gene

  • Protein details for ENSG00000256206 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    B4DEV8-B4DEV8_HUMAN
    Recommended name:
    Proteasome subunit alpha type
    Protein Accession:
    B4DEV8

    Protein attributes for ENSG00000256206 Gene

    Size:
    164 amino acids
    Molecular mass:
    18458 Da
    Quaternary structure:
    • The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

neXtProt entry for ENSG00000256206 Gene

Protein Expression for ENSG00000256206 Gene

Post-translational modifications for ENSG00000256206 Gene

No Post-translational modifications

Other Protein References for ENSG00000256206 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for ENSG00000256206 Gene

Domains & Families for ENSG00000256206 Gene

Gene Families for ENSG00000256206 Gene

Unknown:
  • Belongs to the peptidase T1A family.

Protein Domains for ENSG00000256206 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ENSG00000256206: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ENSG00000256206 Gene

Function for ENSG00000256206 Gene

Molecular function for ENSG00000256206 Gene

UniProtKB/TrEMBL CatalyticActivity:
Reaction=Cleavage of peptide bonds with very broad specificity.; EC=3.4.25.1; Evidence=. ;.
  • B4DEV8

Enzyme Numbers (IUBMB) for ENSG00000256206 Gene

Gene Ontology (GO) - Molecular Function for ENSG00000256206 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004175 endopeptidase activity IBA --
GO:0004298 threonine-type endopeptidase activity IEA --
GO:0008233 peptidase activity IEA --
GO:0016787 hydrolase activity IEA --
genes like me logo Genes that share ontologies with ENSG00000256206: view

Animal Model Products

No data available for Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ENSG00000256206 Gene

Localization for ENSG00000256206 Gene

Gene Ontology (GO) - Cellular Components for ENSG00000256206 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA --
GO:0005737 cytoplasm IBA --
GO:0005839 proteasome core complex IBA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with ENSG00000256206: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for ENSG00000256206 Gene

Pathways & Interactions for ENSG00000256206 Gene

PathCards logo

SuperPathways for ENSG00000256206 Gene

No Data Available

Interacting Proteins for ENSG00000256206 Gene

Gene Ontology (GO) - Biological Process for ENSG00000256206 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006508 proteolysis IEA --
GO:0006511 ubiquitin-dependent protein catabolic process IEA --
GO:0010498 proteasomal protein catabolic process IBA --
GO:0010499 proteasomal ubiquitin-independent protein catabolic process IBA --
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IBA --
genes like me logo Genes that share ontologies with ENSG00000256206: view

No data available for Pathways by source and SIGNOR curated interactions for ENSG00000256206 Gene

Drugs & Compounds for ENSG00000256206 Gene

No Compound Related Data Available

Transcripts for ENSG00000256206 Gene

mRNA/cDNA for ENSG00000256206 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for ENSG00000256206 Gene

No ASD Table

Relevant External Links for ENSG00000256206 Gene

GeneLoc Exon Structure for
ENSG00000256206

Expression for ENSG00000256206 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ENSG00000256206 Gene

mRNA expression in normal human tissues for ENSG00000256206 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from MOPED for ENSG00000256206 Gene



Protein tissue co-expression partners for ENSG00000256206 Gene

genes like me logo Genes that share expression patterns with ENSG00000256206: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ENSG00000256206 Gene

Orthologs for ENSG00000256206 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ENSG00000256206 Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia Psma1 35
  • 47 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 47 (a)
OneToMany
cow
(Bos Taurus)
Mammalia PSMA1 35
  • 47 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 46 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 35
  • 7 (a)
ManyToMany
chicken
(Gallus gallus)
Aves PSMA1 35
  • 46 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 46 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii psma1 35
  • 46 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta Pros35 35
  • 27 (a)
ManyToMany
Prosalpha6T 35
  • 25 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea pas-6 35
  • 28 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes PRE5 35
  • 29 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.5765 35
  • 35 (a)
OneToMany
Species where no ortholog for ENSG00000256206 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ENSG00000256206 Gene

ENSEMBL:
Gene Tree for ENSG00000256206 (if available)
TreeFam:
Gene Tree for ENSG00000256206 (if available)

Paralogs for ENSG00000256206 Gene

Pseudogenes.org Pseudogenes for ENSG00000256206 Gene

genes like me logo Genes that share paralogs with ENSG00000256206: view

Variants for ENSG00000256206 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Additional Variant Information for ENSG00000256206 Gene

Disorders for ENSG00000256206 Gene

No disorders were found for ENSG00000256206 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for ENSG00000256206 Gene

Publications for ENSG00000256206 Gene

  1. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor TD … Sakaki Y (Nature 2006) 13 58

No data available for External Links for ENSG00000256206 Gene

Products for ENSG00000256206 Gene

Sources for ENSG00000256206 Gene

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