Aliases for ENSG00000255292 Gene

Aliases for ENSG00000255292 Gene

  • Succinate Dehydrogenase [Ubiquinone] Cytochrome B Small Subunit 13
  • Novel Transcript 5
  • AP002884.2 5

External Ids for ENSG00000255292 Gene

Previous GeneCards Identifiers for ENSG00000255292 Gene

  • GC11P111957

Summaries for ENSG00000255292 Gene

GeneCards Summary for ENSG00000255292 Gene

ENSG00000255292 is a Protein Coding gene. An important paralog of this gene is SDHD.

Additional gene information for ENSG00000255292 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ENSG00000255292 Gene

Genomics for ENSG00000255292 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for ENSG00000255292 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ENSG00000255292 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for ENSG00000255292 Gene

Latest Assembly
chr11:112,086,903-112,193,805
(GRCh38/hg38)
Size:
106,903 bases
Orientation:
Plus strand

Previous Assembly
chr11:111,957,627-112,064,528
(GRCh37/hg19 by Ensembl)
Size:
106,902 bases
Orientation:
Plus strand

Genomic View for ENSG00000255292 Gene

Genes around ENSG00000255292 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ENSG00000255292 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ENSG00000255292 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for RefSeq DNA sequence for ENSG00000255292 Gene

Proteins for ENSG00000255292 Gene

  • Protein details for ENSG00000255292 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    H3BRW5-H3BRW5_HUMAN
    Recommended name:
    Succinate dehydrogenase [ubiquinone] cytochrome b small subunit
    Protein Accession:
    H3BRW5

    Protein attributes for ENSG00000255292 Gene

    Size:
    140 amino acids
    Molecular mass:
    15501 Da
    Quaternary structure:
    • Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
    • Component of complex II composed of four subunits: the flavoprotein (FP) sdha, iron-sulfur protein (IP) sdhb, and a cytochrome b560 composed of sdhc and sdhd.

neXtProt entry for ENSG00000255292 Gene

Post-translational modifications for ENSG00000255292 Gene

No Post-translational modifications

Other Protein References for ENSG00000255292 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for ENSG00000255292 Gene

Domains & Families for ENSG00000255292 Gene

Gene Families for ENSG00000255292 Gene

Unknown:
  • Belongs to the CybS family.

Protein Domains for ENSG00000255292 Gene

InterPro:
genes like me logo Genes that share domains with ENSG00000255292: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for ENSG00000255292 Gene

Function for ENSG00000255292 Gene

Molecular function for ENSG00000255292 Gene

UniProtKB/TrEMBL Function:
Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
  • H3BRW5

Phenotypes From GWAS Catalog for ENSG00000255292 Gene

Gene Ontology (GO) - Molecular Function for ENSG00000255292 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ENSG00000255292: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ENSG00000255292 Gene

Localization for ENSG00000255292 Gene

Gene Ontology (GO) - Cellular Components for ENSG00000255292 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion IEA --
GO:0005740 mitochondrial envelope IEA --
GO:0005743 mitochondrial inner membrane IEA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with ENSG00000255292: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for ENSG00000255292 Gene

Pathways & Interactions for ENSG00000255292 Gene

PathCards logo

SuperPathways for ENSG00000255292 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ENSG00000255292 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006099 tricarboxylic acid cycle IEA --
GO:0055114 oxidation-reduction process IEA --
genes like me logo Genes that share ontologies with ENSG00000255292: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for ENSG00000255292 Gene

Drugs & Compounds for ENSG00000255292 Gene

No Compound Related Data Available

Transcripts for ENSG00000255292 Gene

mRNA/cDNA for ENSG00000255292 Gene

3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for ENSG00000255292 Gene

No ASD Table

Relevant External Links for ENSG00000255292 Gene

GeneLoc Exon Structure for
ENSG00000255292

Expression for ENSG00000255292 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ENSG00000255292 Gene

mRNA expression in normal human tissues for ENSG00000255292 Gene
genes like me logo Genes that share expression patterns with ENSG00000255292: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ENSG00000255292 Gene

Orthologs for ENSG00000255292 Gene

This gene was present in the common ancestor of animals.

Orthologs for ENSG00000255292 Gene

Organism Taxonomy Gene Similarity Type Details
Cow
(Bos Taurus)
Mammalia SDHD 30
  • 59 (a)
OneToMany
Mouse
(Mus musculus)
Mammalia Sdhd 30
  • 54 (a)
OneToMany
Oppossum
(Monodelphis domestica)
Mammalia -- 30
  • 44 (a)
OneToMany
Chicken
(Gallus gallus)
Aves SDHD 30
  • 39 (a)
OneToMany
Lizard
(Anolis carolinensis)
Reptilia -- 30
  • 46 (a)
OneToMany
Zebrafish
(Danio rerio)
Actinopterygii sdhdb 30
  • 35 (a)
ManyToMany
sdhda 30
  • 33 (a)
ManyToMany
Fruit Fly
(Drosophila melanogaster)
Insecta CG10219 30
  • 18 (a)
OneToMany
Worm
(Caenorhabditis elegans)
Secernentea sdhd-1 30
  • 19 (a)
OneToMany
Species where no ortholog for ENSG00000255292 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)

Evolution for ENSG00000255292 Gene

ENSEMBL:
Gene Tree for ENSG00000255292 (if available)
TreeFam:
Gene Tree for ENSG00000255292 (if available)

Paralogs for ENSG00000255292 Gene

Paralogs for ENSG00000255292 Gene

genes like me logo Genes that share paralogs with ENSG00000255292: view

Variants for ENSG00000255292 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , dbSNP identifiers (rs#s) for variants without ClinVar clinical significance , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Additional Variant Information for ENSG00000255292 Gene

Disorders for ENSG00000255292 Gene

No disorders were found for ENSG00000255292 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for ENSG00000255292 Gene

Publications for ENSG00000255292 Gene

  1. Initial characterization of the human central proteome. (PMID: 21269460) Burkard TR … Colinge J (BMC systems biology 2011) 13
  2. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor TD … Sakaki Y (Nature 2006) 13

No data available for Mastermind for ENSG00000255292 Gene

Products for ENSG00000255292 Gene

Sources for ENSG00000255292 Gene