Aliases for ENSG00000250349 Gene

Aliases for ENSG00000250349 Gene

  • Novel Proline Rich Gla (G-Carboxyglutamic Acid) 1 (PRRG1) And Tetraspanin 7 (TSPAN7) Protein 5
  • Tetraspanin 13
  • AF241726.2 5

External Ids for ENSG00000250349 Gene

Previous GeneCards Identifiers for ENSG00000250349 Gene

  • GC0XP037210

Summaries for ENSG00000250349 Gene

GeneCards Summary for ENSG00000250349 Gene

ENSG00000250349 is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include calcium ion binding. An important paralog of this gene is TSPAN7.

Additional gene information for ENSG00000250349 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ENSG00000250349 Gene

Genomics for ENSG00000250349 Gene

GeneHancer (GH) Regulatory Elements for ENSG00000250349 Gene

Promoters and enhancers for ENSG00000250349 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH0XJ037346 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE CraniofacialAtlas 500.7 -0.6 -566 4.9 NRF1 POLR2G ZIC2 POLR2A ZBTB10 ZBTB26 MYC TGIF2 TEAD1 CTBP1 ENSG00000250349 PRRG1 piR-55194-434
GH0XJ037381 Enhancer 1 Ensembl ENCODE 0.3 +32.1 32070 1.6 ZSCAN5C ZNF10 EP300 OSR2 NFIC ZBTB17 FOS CEBPB JUN KLF8 piR-57135-144 ENSG00000250349 PRRG1
GH0XJ037361 Enhancer 0.4 Ensembl 0.4 +12.4 12371 0.2 ZNF316 MAFK EMSY ENSG00000250349 PRRG1 piR-57135-144
GH0XJ037453 Promoter/Enhancer 1.1 EPDnew Ensembl ENCODE 0.1 +105.5 105537 2.5 EP300 OSR2 ZNF263 FOS CEBPB JUN RCOR1 JUND IKZF3 ZNF843 PRRG1 piR-53338-142 ENSG00000241607 ENSG00000250349
GH0XJ037371 Enhancer 0.3 Ensembl 0.4 +22.4 22371 1.4 ZIC2 ZNF680 ENSG00000250349 PRRG1 piR-57135-144
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ENSG00000250349 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ENSG00000250349 Gene

Genomic Locations for ENSG00000250349 Gene
chrX:37,349,330-38,687,674
(GRCh38/hg38)
Size:
1,338,345 bases
Orientation:
Plus strand
chrX:37,208,583-38,546,928
(GRCh37/hg19)
Size:
1,338,346 bases
Orientation:
Plus strand

Genomic View for ENSG00000250349 Gene

Genes around ENSG00000250349 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ENSG00000250349 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ENSG00000250349 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for RefSeq DNA sequence for ENSG00000250349 Gene

Proteins for ENSG00000250349 Gene

  • Protein details for ENSG00000250349 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    B4E171-B4E171_HUMAN
    Recommended name:
    Tetraspanin
    Protein Accession:
    B4E171

    Protein attributes for ENSG00000250349 Gene

    Size:
    279 amino acids
    Molecular mass:
    31091 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ENSG00000250349 Gene

Protein Expression for ENSG00000250349 Gene

Post-translational modifications for ENSG00000250349 Gene

No Post-translational modifications

Other Protein References for ENSG00000250349 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for ENSG00000250349 Gene

Domains & Families for ENSG00000250349 Gene

Gene Families for ENSG00000250349 Gene

Unknown:
  • Belongs to the tetraspanin (TM4SF) family.
Human Protein Atlas (HPA):
  • Predicted membrane proteins
genes like me logo Genes that share domains with ENSG00000250349: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for ENSG00000250349 Gene

Function for ENSG00000250349 Gene

Phenotypes From GWAS Catalog for ENSG00000250349 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ENSG00000250349 Gene

Localization for ENSG00000250349 Gene

Gene Ontology (GO) - Cellular Components for ENSG00000250349 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
GO:0005887 integral component of plasma membrane IBA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with ENSG00000250349: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for ENSG00000250349 Gene

Pathways & Interactions for ENSG00000250349 Gene

PathCards logo

SuperPathways for ENSG00000250349 Gene

No Data Available

Interacting Proteins for ENSG00000250349 Gene

STRING Interaction Network Preview (showing top 5 STRING interactants - click image to see top 25)
STRING Interaction Network
Selected Interacting proteins: ENSP00000417050 for ENSG00000250349 Gene via STRING

;

Gene Ontology (GO) - Biological Process for ENSG00000250349 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ENSG00000250349 Gene

Drugs & Compounds for ENSG00000250349 Gene

No Compound Related Data Available

Transcripts for ENSG00000250349 Gene

mRNA/cDNA for ENSG00000250349 Gene

1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for ENSG00000250349 Gene

No ASD Table

Relevant External Links for ENSG00000250349 Gene

GeneLoc Exon Structure for
ENSG00000250349

Expression for ENSG00000250349 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ENSG00000250349 Gene

mRNA expression in normal human tissues for ENSG00000250349 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from MaxQB and MOPED for ENSG00000250349 Gene



Evidence on tissue expression from TISSUES for ENSG00000250349 Gene

  • Blood(2)
genes like me logo Genes that share expression patterns with ENSG00000250349: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ENSG00000250349 Gene

Orthologs for ENSG00000250349 Gene

This gene was present in the common ancestor of animals.

Orthologs for ENSG00000250349 Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia Tspan7 31
  • 89 (a)
ManyToMany
Gm5334 31
  • 59 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia TSPAN7 31
  • 88 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 31
  • 86 (a)
ManyToMany
-- 31
  • 64 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 31
  • 84 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 31
  • 74 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 31
  • 82 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 31
  • 84 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii tspan7b 31
  • 75 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea tsp-14 31
  • 12 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.7928 31
  • 34 (a)
OneToMany
Species where no ortholog for ENSG00000250349 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ENSG00000250349 Gene

ENSEMBL:
Gene Tree for ENSG00000250349 (if available)
TreeFam:
Gene Tree for ENSG00000250349 (if available)

Paralogs for ENSG00000250349 Gene

Variants for ENSG00000250349 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Additional dbSNP identifiers (rs#s) , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Additional Variant Information for ENSG00000250349 Gene

Disorders for ENSG00000250349 Gene

No disorders were found for ENSG00000250349 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for ENSG00000250349 Gene

Publications for ENSG00000250349 Gene

  1. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross MT … Bentley DR (Nature 2005) 13 54

No data available for Mastermind for ENSG00000250349 Gene

Products for ENSG00000250349 Gene

Sources for ENSG00000250349 Gene