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Aliases for ENSG00000228144 Gene

Aliases for ENSG00000228144 Gene

  • AC078927.1 5

External Ids for ENSG00000228144 Gene

Previous GeneCards Identifiers for ENSG00000228144 Gene

  • GC12P066517
  • GC12M066517

Summaries for ENSG00000228144 Gene

GeneCards Summary for ENSG00000228144 Gene

ENSG00000228144 is a Protein Coding gene. An important paralog of this gene is TMBIM4.

Additional gene information for ENSG00000228144 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ENSG00000228144 Gene

Genomics for ENSG00000228144 Gene

GeneHancer (GH) Regulatory Elements for ENSG00000228144 Gene

Promoters and enhancers for ENSG00000228144 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12J066168 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 650.7 +0.5 451 2.7 FEZF1 DMAP1 IRF4 YY1 ZNF213 E2F8 ZNF416 ZNF143 ZNF263 SP3 ENSG00000228144 TMBIM4 LEMD3 LINC02425 OSBPL9P4 LOC105369808 ENSG00000256915 LLPH-DT LLPH
GH12J066234 Promoter/Enhancer 1.9 FANTOM5 Ensembl ENCODE dbSUPER 11.7 -65.4 -65372 1.7 ATF1 ARNT SIN3A ZBTB40 RFX5 ZNF335 GLIS2 ATF7 SMARCA5 YY2 RBMS1P1 IRAK3 TMBIM4 ENSG00000228144 HELB ENSG00000256072 LLPH LLPH-DT MIR6502
GH12J066235 Enhancer 1 ENCODE dbSUPER 11.7 -64.2 -64201 0.2 PKNOX1 ATF1 ZSCAN4 SIN3A RFX5 SCRT2 ZNF143 FOS ATF7 RUNX3 RBMS1P1 IRAK3 ENSG00000228144 TMBIM4 ENSG00000256072 LLPH LLPH-DT HELB PIR44949
GH12J066129 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 0.3 +38.6 38557 3.5 PKNOX1 ARID4B SIN3A FEZF1 DMAP1 YY1 POLR2B E2F8 ZNF207 ZNF143 LLPH-DT LLPH IRAK3 HELB TMBIM4 ENSG00000228144
GH12J066144 Enhancer 1.2 Ensembl ENCODE dbSUPER 0.3 +24.7 24749 1.3 ELF3 FOXA2 NFIB RAD21 YY1 EGR1 THAP11 ZNF654 RXRA CEBPB TMBIM4 LLPH ENSG00000228144
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ENSG00000228144 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ENSG00000228144 Gene

Genomic Locations for ENSG00000228144 Gene
chr12:66,123,917-66,169,985
(GRCh38/hg38)
Size:
46,069 bases
Orientation:
Minus strand
chr12:66,517,697-66,563,765
(GRCh37/hg19)
Size:
46,069 bases
Orientation:
Minus strand

Genomic View for ENSG00000228144 Gene

Genes around ENSG00000228144 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ENSG00000228144 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ENSG00000228144 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for RefSeq DNA sequence for ENSG00000228144 Gene

Proteins for ENSG00000228144 Gene

  • Protein details for ENSG00000228144 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    F6UZH7-F6UZH7_HUMAN
    Recommended name:
    Uncharacterized protein
    Protein Accession:
    F6UZH7

    Protein attributes for ENSG00000228144 Gene

    Size:
    168 amino acids
    Molecular mass:
    19062 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ENSG00000228144 Gene

Protein Expression for ENSG00000228144 Gene

Post-translational modifications for ENSG00000228144 Gene

No Post-translational modifications

Other Protein References for ENSG00000228144 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for ENSG00000228144 Gene

Domains & Families for ENSG00000228144 Gene

Gene Families for ENSG00000228144 Gene

Unknown:
  • Belongs to the BI1 family.

Protein Domains for ENSG00000228144 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ENSG00000228144: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ENSG00000228144 Gene

Function for ENSG00000228144 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ENSG00000228144 Gene

Localization for ENSG00000228144 Gene

Gene Ontology (GO) - Cellular Components for ENSG00000228144 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with ENSG00000228144: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for ENSG00000228144 Gene

Pathways & Interactions for ENSG00000228144 Gene

SuperPathways for ENSG00000228144 Gene

No Data Available

Interacting Proteins for ENSG00000228144 Gene

STRING Interaction Network Preview (showing 4 interactants - click image to see details)
http://version10.5.string-db.org/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000454670%0d%0a9606.ENSP00000356919%0d%0a9606.ENSP00000364349%0d%0a9606.ENSP00000335153%0d%0a9606.ENSP00000325875%0d%0a
Selected Interacting proteins: ENSP00000454670 for ENSG00000228144 Gene via STRING

Gene Ontology (GO) - Biological Process for ENSG00000228144 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ENSG00000228144 Gene

Drugs & Compounds for ENSG00000228144 Gene

No Compound Related Data Available

Transcripts for ENSG00000228144 Gene

mRNA/cDNA for ENSG00000228144 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ENSG00000228144 Gene

No ASD Table

Relevant External Links for ENSG00000228144 Gene

GeneLoc Exon Structure for
ENSG00000228144

Expression for ENSG00000228144 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ENSG00000228144 Gene

mRNA expression in normal human tissues for ENSG00000228144 Gene

Protein differential expression in normal tissues from HIPED for ENSG00000228144 Gene

This gene is overexpressed in Testis (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from MOPED for ENSG00000228144 Gene



Protein tissue co-expression partners for ENSG00000228144 Gene

genes like me logo Genes that share expression patterns with ENSG00000228144: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ENSG00000228144 Gene

Orthologs for ENSG00000228144 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ENSG00000228144 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia -- 34
  • 60 (a)
OneToMany
cow
(Bos Taurus)
Mammalia CGI-119 34
  • 58 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Tmbim4 34
  • 55 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia -- 34
  • 55 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 55 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 46 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 34
  • 50 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 51 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii tmbim4 34
  • 42 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG33673 34
  • 11 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea tmbi-4 34
  • 18 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes BXI1 34
  • 17 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.8799 34
  • 31 (a)
OneToMany
Species where no ortholog for ENSG00000228144 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ENSG00000228144 Gene

ENSEMBL:
Gene Tree for ENSG00000228144 (if available)
TreeFam:
Gene Tree for ENSG00000228144 (if available)

Paralogs for ENSG00000228144 Gene

Paralogs for ENSG00000228144 Gene

genes like me logo Genes that share paralogs with ENSG00000228144: view

Variants for ENSG00000228144 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Additional Variant Information for ENSG00000228144 Gene

Disorders for ENSG00000228144 Gene

No disorders were found for ENSG00000228144 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for ENSG00000228144 Gene

Publications for ENSG00000228144 Gene

No publications were found for ENSG00000228144 Gene.

Products for ENSG00000228144 Gene

Sources for ENSG00000228144 Gene

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