Aliases for ENOX1 Gene
External Ids for ENOX1 Gene
Previous GeneCards Identifiers for ENOX1 Gene
The protein encoded by this gene is involved in plasma membrane electron transport pathways. The encoded protein has both a hydroquinone (NADH) oxidase activity and a protein disulfide-thiol interchange activity. The two activities cycle with a periodicity of 24 minutes, with one activity being at its peak when the other is at its lowest. [provided by RefSeq, Dec 2016]
GeneCards Summary for ENOX1 Gene
ENOX1 (Ecto-NOX Disulfide-Thiol Exchanger 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and oxidoreductase activity. An important paralog of this gene is ENOX2.
UniProtKB/Swiss-Prot for ENOX1 Gene
Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 24 minutes and play a role in control of the ultradian cellular biological clock.