Aliases for ENO2 Gene
Aliases for ENO2 Gene
External Ids for ENO2 Gene
- HGNC: 3353
- Entrez Gene: 2026
- Ensembl: ENSG00000111674
- OMIM: 131360
- UniProtKB: P09104
Previous GeneCards Identifiers for ENO2 Gene
- GC12M006942
- GC12M007028
- GC12P006902
- GC12P006894
- GC12P006897
- GC12P006898
- GC12P007023
- GC12P007037
- GC12P007067
- GC12P007116
- GC12P007149
Summaries for ENO2 Gene
-
This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates. [provided by RefSeq, Jul 2008]
GeneCards Summary for ENO2 Gene
ENO2 (Enolase 2) is a Protein Coding gene. Diseases associated with ENO2 include Granular Cell Tumor and Small Cell Carcinoma. Among its related pathways are Metabolism and HIF-1 signaling pathway. Gene Ontology (GO) annotations related to this gene include magnesium ion binding and phosphopyruvate hydratase activity. An important paralog of this gene is ENO1.
UniProtKB/Swiss-Prot for ENO2 Gene
-
Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity).
Additional gene information for ENO2 Gene
- Monarch Initiative
- Search for ENO2 at DataMed
- Search for ENO2 at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ENO2 Gene
Genomics for ENO2 Gene
GeneHancer (GH) Regulatory Elements for ENO2 Gene
Promoters and enhancers for ENO2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around ENO2 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the ENO2 gene promoter:
-
- STAT3
- AP-1
- p53
- GR-alpha
- GR
- GR-beta
- ATF-2
Regulatory Element Products
Genomic Locations for ENO2 Gene
Genomic Locations for ENO2 Gene
- chr12:6,913,745-6,923,698
- (GRCh38/hg38)
- Size:
- 9,954 bases
- Orientation:
- Plus strand
- chr12:7,022,909-7,032,861
- (GRCh37/hg19)
- Size:
- 9,953 bases
- Orientation:
- Plus strand
Genomic View for ENO2 Gene
Genes around ENO2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12p13.31 by Entrez Gene
- 12p13.31 by HGNC
- 12p13.31 by Ensembl
ENO2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ENO2 Gene
Proteins for ENO2 Gene
-
Protein details for ENO2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P09104-ENOG_HUMAN
- Recommended name:
- Gamma-enolase
- Protein Accession:
- P09104
- B7Z2X9
- Q96J33
Protein attributes for ENO2 Gene
- Size:
- 434 amino acids
- Molecular mass:
- 47269 Da
- Cofactor:
- Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
- Quaternary structure:
-
- Mammalian enolase is composed of 3 isozyme subunits, alpha, beta and gamma, which can form homodimers or heterodimers which are cell-type and development-specific.
- SequenceCaution:
-
- Sequence=AAA52388.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Three dimensional structures from OCA and Proteopedia for ENO2 Gene
Protein Expression for ENO2 Gene
Post-translational modifications for ENO2 Gene
Other Protein References for ENO2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for ENO2 (Enolase 2/Neuron-specific Enolase)
-
Custom Antibody ServicesOriGene Antibodies for ENO2
- Novus Biologicals Antibodies for ENO2
-
Abcam antibodies for ENO2
- Invitrogen Antibodies for ENO2 (AFLGC-ENO2)
- GeneTex ENO2 Antibody for ENO2
-
Santa Cruz Biotechnology (SCBT) Antibodies for ENO2
- Sino Biological Antibodies for ENO2
Protein Products
-
OriGene Purified Proteins for ENO2
- Search Origene for MassSpec and Protein Over-expression Lysates for ENO2
- Origene Custom Protein Services for ENO2
- Sino Biological Recombinant Proteins for ENO2
- Browse Sino Biological Cell Lysates
- ProSpec Recombinant Proteins for ENO2
- Search GeneTex for Proteins for ENO2
-
Abcam proteins for ENO2
Assay Products
- R&D Systems ELISAs, Luminex Assays, Proteome Profiler Antibody Arrays, and other biochemical assays for ENO2 (Enolase 2/Neuron-specific Enolase)
- Novus Biologicals ELISA Kits for ENO2
-
Abcam assays for ENO2
No data available for DME Specific Peptides for ENO2 Gene
Domains & Families for ENO2 Gene
Gene Families for ENO2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Candidate cardiovascular disease genes
- Enzymes
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for ENO2 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for ENO2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P09104- Family:
-
- Belongs to the enolase family.
Function for ENO2 Gene
Molecular function for ENO2 Gene
- UniProtKB/Swiss-Prot Function:
- Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity).
- UniProtKB/Swiss-Prot CatalyticActivity:
- 2-phospho-D-glycerate = phosphoenolpyruvate + H(2)O.
- UniProtKB/Swiss-Prot Induction:
- Levels of ENO2 increase dramatically in cardiovascular accidents, cerebral trauma, brain tumors and Creutzfeldt-Jakob disease.
- GENATLAS Biochemistry:
- enolase 2,gamma subunit,neuronal (2-phospho-D-glycerate hydrolase),glycolysis,energy pathway
Enzyme Numbers (IUBMB) for ENO2 Gene
Phenotypes From GWAS Catalog for ENO2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000287 | magnesium ion binding | IEA | -- |
| GO:0004634 | phosphopyruvate hydratase activity | TAS | -- |
| GO:0005515 | protein binding | IPI | 21044950 |
| GO:0016829 | lyase activity | IEA | -- |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for ENO2 Gene
- MGI mutant phenotypes for ENO2:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for ENO2:
Animal Model Products
-
Taconic Biosciences Mouse Models for ENO2
- Cyagen custom Knockout/knockin (KOKI) mouse models for ENO2
-
CRISPR Products
-
OriGene CRISPR knockouts for ENO2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ENO2
- genomics-online: gRNA clones - Search results for 146 available ENO2 gene related products
- Overview of 146 available ENO2 gene related products
- Applied Biological Materials CRISPR for ENO2
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ENO2
- GenScript: Design CRISPR guide RNA sequences for ENO2
miRNA for ENO2 Gene
- miRTarBase miRNAs that target ENO2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ENO2
- Browse OriGene Inhibitory RNA Products For ENO2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ENO2
- genomics-online: shRNA clones - Search results for 146 available ENO2 gene related products
- Overview of 146 available ENO2 gene related products
Clone Products
- Sino Biological Human cDNA Clone for ENO2
- Addgene plasmids for ENO2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ENO2
- Applied Biological Materials Clones for ENO2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for ENO2
No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ENO2 Gene
Localization for ENO2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ENO2 Gene
- Cytoplasm. Cell membrane. Note=Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form. {ECO:0000250}.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| cytosol | 5 |
| plasma membrane | 4 |
| cytoskeleton | 3 |
| nucleus | 3 |
| mitochondrion | 2 |
| endoplasmic reticulum | 1 |
| lysosome | 1 |
- Cytosol (3)
- Plasma membrane (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000015 | phosphopyruvate hydratase complex | IEA | -- |
| GO:0001917 | photoreceptor inner segment | IEA | -- |
| GO:0005615 | extracellular space | HDA | 22664934 |
| GO:0005622 | intracellular | IEA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
Pathways & Interactions for ENO2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Glucose metabolism |
.52
.46
|
.35
.01
|
| 2 | Carbon metabolism | ||
| 3 | Metabolism |
.37
|
|
| 4 | HIF-1 signaling pathway | ||
| 5 | Deadenylation-dependent mRNA decay |
.46
|
|
Pathways by source for ENO2 Gene
4 BioSystems pathways for ENO2 Gene
5 Reactome pathways for ENO2 Gene
6 KEGG pathways for ENO2 Gene
1 GeneGo (Thomson Reuters) pathway for ENO2 Gene
2 Cell Signaling Technology pathways for ENO2 Gene
UniProtKB/Swiss-Prot P09104-ENOG_HUMAN
- Pathway: Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.
Interacting Proteins for ENO2 Gene
Selected Interacting proteins:
ENSP00000229277
P09104-ENOG_HUMAN
for ENO2 Gene via
STRING
UniProtKB
IID
GPS-Prot Interaction Network for ENO2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006094 | gluconeogenesis | TAS | -- |
| GO:0006096 | glycolytic process | ISS | 22087329 |
| GO:0061621 | canonical glycolysis | TAS | -- |
No data available for SIGNOR curated interactions for ENO2 Gene
Drugs & Compounds for ENO2 Gene
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| 3-Dehydroquinate |
|
|
Drug Products
Transcripts for ENO2 Gene
mRNA/cDNA for ENO2 Gene
- (1) REFSEQ mRNAs :
- (12) Additional mRNA sequences :
- (11) Selected AceView cDNA sequences:
- (14) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000537688 547 bps (uc058knj.1)
- ENST00000541477 2549 bps (uc009zfi.2)
- ENST00000537838 541 bps (uc058knk.1)
- ENST00000536199 823 bps (uc058knl.1)
- ENST00000538763 1646 bps (uc058knm.1)
Unigene Clusters for ENO2 Gene
CRISPR Products
-
OriGene CRISPR knockouts for ENO2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ENO2
- genomics-online: gRNA clones - Search results for 146 available ENO2 gene related products
- Overview of 146 available ENO2 gene related products
- Applied Biological Materials CRISPR for ENO2
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ENO2
- GenScript: Design CRISPR guide RNA sequences for ENO2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ENO2
- Browse OriGene Inhibitory RNA Products For ENO2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ENO2
- genomics-online: shRNA clones - Search results for 146 available ENO2 gene related products
- Overview of 146 available ENO2 gene related products
Clone Products
- Sino Biological Human cDNA Clone for ENO2
- Addgene plasmids for ENO2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ENO2
- Applied Biological Materials Clones for ENO2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | · | 2c | · | 2d | · | 2e | ^ | 3 | ^ | 4a | · | 4b | · | 4c | · | 4d | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8a | · | 8b | · | 8c | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12a | · |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP12: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP13: | - | - |
| ExUns: | 12b |
|---|---|
| SP1: | |
| SP2: | |
| SP3: | |
| SP4: | |
| SP5: | |
| SP6: | |
| SP7: | |
| SP8: | |
| SP9: | |
| SP10: | |
| SP11: | |
| SP12: | |
| SP13: |
Expression for ENO2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
- Neural Tube (Nervous System)
- NULL (Uncategorized)
- Inner Cell Mass (Early Embryonic Tissues)
- Bone (Muscoskeletal System)
- Mesenchymal Stem Cells
-
Gonad (Reproductive System)
- Testis Somatic Cells Primitive Gonad
-
Testis (Reproductive System)
- Testis Somatic Cells Primitive Gonad
-
Blood (Hematopoietic System)
- Hematopoietic Stem Cells Hematopoietic Bone Marrow
- Pancreas (Endocrine System)
- Motor Neurons (Nervous System)
- Spinal Cord (Nervous System)
mRNA differential expression in normal tissues according to GTEx for ENO2 Gene
This gene is overexpressed in Brain - Cerebellar Hemisphere (x6.0), Brain - Cerebellum (x5.5), Brain - Frontal Cortex (BA9) (x4.6), and Brain - Cortex (x4.3).
This gene is overexpressed in Retina (17.2), Brain (13.9), and Saliva (6.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ENO2 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of ENO2 Gene:
ENO2SOURCE GeneReport for Unigene cluster for ENO2 Gene:
Hs.511915mRNA Expression by UniProt/SwissProt for ENO2 Gene:
P09104-ENOG_HUMAN
Tissue specificity:
The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons.
Evidence on tissue expression from TISSUES for ENO2 Gene
- Nervous system(5)
- Eye(4.9)
- Blood(4.6)
- Liver(4.5)
- Kidney(4.1)
- Lung(3.4)
- Adrenal gland(2.9)
- Intestine(2.9)
- Lymph node(2.9)
- Muscle(2.9)
- Pancreas(2.9)
- Skin(2.7)
- Thyroid gland(2.7)
- Stomach(2.5)
- Gall bladder(2.3)
- Heart(2.3)
- Bone marrow(2.2)
Primer Products
-
OriGene qPCR primer pairs for ENO2
-
OriGene qPCR primer pairs and template standards for ENO2
- genomics-online: primer clones - Search results for 146 available ENO2 gene related products
- Overview of 146 available ENO2 gene related products
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for ENO2 Gene
Orthologs for ENO2 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| dog (Canis familiaris) |
Mammalia | ENO2 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | ENO2 34 33 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Eno2 16 34 33 |
|
||
| rat (Rattus norvegicus) |
Mammalia | LOC100911625 33 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | ENO2 34 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | ENO2 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ENO2 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | ENO2 34 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | eno2 34 33 |
|
OneToOne | |
| fruit fly (Drosophila melanogaster) |
Insecta | Eno 34 35 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | enol-1 34 |
|
OneToMany | |
| A. gosspyii yeast (Ashbya gossypii) |
Saccharomycetes | AGOS_AER294C 33 |
|
||
| K. lactis yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0A09185g 33 |
|
||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | ENO1 34 33 |
|
ManyToMany | |
| ENO2 34 |
|
ManyToMany | |||
| ERR2 34 |
|
ManyToMany | |||
| ERR1 34 |
|
ManyToMany | |||
| ERR3 34 |
|
ManyToMany | |||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.10219 34 |
|
OneToMany | |
| bread mold (Neurospora crassa) |
Ascomycetes | NCU10042 33 |
|
||
| fission yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | eno101 33 |
|
- Species where no ortholog for ENO2 was found in the sources mined by GeneCards:
-
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- chimpanzee (Pan troglodytes)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
Evolution for ENO2 Gene
- ENSEMBL:
- Gene Tree for ENO2 (if available)
- TreeFam:
- Gene Tree for ENO2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for ENO2: view image
Paralogs for ENO2 Gene
Variants for ENO2 Gene
| SNP ID | Clin | Chr 12 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000634103 | -- | 6,916,457(+) | C/T | coding_sequence_variant, synonymous_variant | |
| rs1001276024 | -- | 6,923,220(+) | C/T | 3_prime_UTR_variant | |
| rs1001391324 | -- | 6,916,164(+) | A/C | intron_variant | |
| rs1002345369 | -- | 6,923,375(+) | T/C | 3_prime_UTR_variant | |
| rs1002861692 | -- | 6,919,881(+) | G/A | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1035811 | CNV | gain | 25217958 |
| nsv1047373 | CNV | gain | 25217958 |
| nsv1129363 | OTHER | inversion | 24896259 |
| nsv509453 | CNV | insertion | 20534489 |
| nsv557261 | CNV | loss | 21841781 |
| nsv832324 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
14.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.56;
12.09% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ENO2 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ENO2 Gene
Disorders for ENO2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| granular cell tumor |
|
|
| small cell carcinoma |
|
|
| neuroendocrine tumor |
|
|
| melanotic neuroectodermal tumor |
|
|
| askin's tumor |
|
|
Search ENO2 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for ENO2
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for ENO2 Gene
Publications for ENO2 Gene
- The estrogen hypothesis of schizophrenia implicates glucose metabolism: association study in three independent samples. (PMID: 18460190) Olsen L … Werge T (BMC medical genetics 2008) 3 22 44 58
- Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease. (PMID: 19204726) Chapuis J … Lambert JC (Molecular psychiatry 2009) 3 44 58
- Serum concentrations of s100b and NSE in migraine. (PMID: 18783450) Teepker M … Schepelmann K (Headache 2009) 3 22 58
- [Changes in plasma S-100 beta and neuron-specific enolase in peri-operative period of orthotopic liver transplantation and its relationship with encephalopathy after operation]. (PMID: 19220958) Sun HY … Li SR (Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 2009) 3 22 58
- Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia. (PMID: 19074885) Enjuanes A … Campo E (Cancer research 2008) 3 44 58
Products for ENO2 Gene
- R&D Systems Antibodies for ENO2 (Enolase 2/Neuron-specific Enolase)
- Browse R&D Systems for Human Recombinant Proteins
- R&D Systems ELISAs, Luminex Assays, Proteome Profiler Antibody Arrays, and other biochemical assays for ENO2 (Enolase 2/Neuron-specific Enolase)
- Browse Human Proteins and Enzymes
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for ENO2
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for ENO2
- Search Origene for MassSpec and Protein Over-expression Lysates for ENO2
- Origene Custom Protein Services for ENO2
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ENO2
- Browse OriGene Inhibitory RNA Products For ENO2
- OriGene qPCR primer pairs for ENO2
- OriGene qPCR primer pairs and template standards for ENO2
- OriGene CRISPR knockouts for ENO2
- OriGene ORF clones in human for ENO2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For ENO2
- GenScript: Next-day shipping of latest version cDNA ORF clones for ENO2 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for ENO2
- GenScript Custom Assay Services for ENO2
- GenScript Custom overexpressing Cell Line Services for ENO2
- GenScript: Design CRISPR guide RNA sequences for ENO2
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for ENO2
- Sino Biological Human cDNA Clone for ENO2
- Sino Biological Recombinant Proteins for ENO2
- Browse Sino Biological Cell Lysates
- Sino Biological Antibodies for ENO2
- Browse Sino Biological Assays
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- Browse cDNA Clones
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- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for ENO2
- Novus Biologicals proteins and lysates for ENO2
- Novus Biologicals ELISA Kits for ENO2
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies
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- Abcam antibodies for ENO2
- Abcam proteins for ENO2
- Abcam assays for ENO2
- Find your target
- Browse Primary Antibodies
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- Search Knockout (KO) Validated Antibodies
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- ProSpec Recombinant Proteins for ENO2
- Taconic Biosciences Mouse Models for ENO2
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for ENO2 (AFLGC-ENO2)
- Cyagen custom Knockout/knockin (KOKI) mouse models for ENO2
- Addgene plasmids for ENO2
- antibodies-online: Search results for 672 available ENO2 Antibodies ranked by validation data
- Compare Top ENO2 Antibodies
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- antibodies-online: Search results for 69 available ENO2 Elisa Kits ranked by validation data
- Compare Top ENO2 Elisa Kits
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- antibodies-online: Search results for 46 available ENO2 Proteins ranked by validation data
- Compare Top ENO2 Proteins
- GeneTex ENO2 Antibody for ENO2
- Search GeneTex for Proteins for ENO2
- Santa Cruz Biotechnology (SCBT) Antibodies for ENO2
- Search Santa Cruz Biotechnology (SCBT) for ENO2 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for ENO2
- Horizon Cell Lines for ENO2
- genomics-online: cdna clones - Search results for 146 available ENO2 gene related products
- Overview of 146 available ENO2 gene related products
- orf clones - Search results for 146 available ENO2 gene related products
- Overview of 146 available ENO2 gene related products
- genomics-online: gRNA clones - Search results for 146 available ENO2 gene related products
- Overview of 146 available ENO2 gene related products
- genomics-online: primer clones - Search results for 146 available ENO2 gene related products
- Overview of 146 available ENO2 gene related products
- genomics-online: shRNA clones - Search results for 146 available ENO2 gene related products
- Overview of 146 available ENO2 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ENO2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ENO2
- GeneCopoeia miRNA 3'UTR Target clone products for ENO2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ENO2
Sources for ENO2 Gene
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- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
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- (13) InterPro
- (14) ProtoNet
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- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
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- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
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- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
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- (108) SCBT
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- (169) Biorbyt