Aliases for ENGASE Gene
External Ids for ENGASE Gene
Previous GeneCards Identifiers for ENGASE Gene
This gene encodes a cytosolic enzyme which catalyzes the hydrolysis of peptides and proteins with mannose modifications to produce free oligosaccharides. [provided by RefSeq, Feb 2012]
GeneCards Summary for ENGASE Gene
ENGASE (Endo-Beta-N-Acetylglucosaminidase) is a Protein Coding gene. Diseases associated with ENGASE include Congenital Disorder Of Deglycosylation and Autosomal Dominant Polycystic Kidney Disease. Among its related pathways are Calnexin/calreticulin cycle and Transport to the Golgi and subsequent modification. Gene Ontology (GO) annotations related to this gene include mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity.
UniProtKB/Swiss-Prot Summary for ENGASE Gene
Endoglycosidase that releases N-glycans from glycoproteins by cleaving the beta-1,4-glycosidic bond in the N,N'-diacetylchitobiose core. Involved in the processing of free oligosaccharides in the cytosol.