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Aliases for EMX2OS Gene

Subcategory (RNA class) for EMX2OS Gene

non-coding RNA

Quality Score for this RNA gene is

13

Aliases for EMX2OS Gene

  • EMX2 Opposite Strand/Antisense RNA 2 3 5
  • EMX2 Opposite Strand/Antisense RNA (Non-Protein Coding) 2 3
  • Empty Spiracles Homeobox 2 Opposite Strand 2 3
  • Empty Spiracles Homolog 2 Opposite Strand 3
  • EMX2 Opposite Strand (Non-Protein Coding) 2
  • Non-Protein Coding RNA 45 2
  • NCRNA00045 3
  • EMX2-AS1 3

External Ids for EMX2OS Gene

Previous GeneCards Identifiers for EMX2OS Gene

  • GC10M118487
  • GC10M119375
  • GC10U900125
  • GC10M119233
  • GC10M112872

Summaries for EMX2OS Gene

GeneCards Summary for EMX2OS Gene

EMX2OS (EMX2 Opposite Strand/Antisense RNA) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with EMX2OS include Hypertension, Essential.

Additional gene information for EMX2OS Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for EMX2OS Gene

Genomics for EMX2OS Gene

GeneHancer (GH) Regulatory Elements for EMX2OS Gene

Promoters and enhancers for EMX2OS Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J117541 Promoter/Enhancer 1.9 EPDnew FANTOM5 ENCODE dbSUPER 650.7 +1.2 1198 5.6 FEZF1 GLI4 ZNF2 YY1 ZNF121 GLIS2 ZNF213 KLF7 KLF13 SP3 EMX2 EMX2OS ENSG00000231104 VAX1
GH10J117438 Enhancer 0.5 ENCODE 5.8 +105.7 105670 1.3 GATAD2A NFIL3 HLF CEBPA CEBPG FOS BCL6 PDZD8 EMX2OS LOC105378502 GC10P117520
GH10J117935 Enhancer 0.3 ENCODE 5.1 -391.5 -391533 1.6 HLF EMX2OS LOC105378504 ENSG00000263041
GH10J117549 Enhancer 1.5 VISTA UCNEbase dbSUPER 0.4 -5.8 -5750 2.3 BCOR SUZ12 TEAD4 TAL1 ZBTB40 CC2D1A TCF12 CCNT2 NCOR1 VEZF1 ENSG00000235198 EMX2OS
GH10J117547 Enhancer 0.6 ENCODE dbSUPER 0.7 -2.6 -2597 0.2 SUZ12 SIN3A ENSG00000235198 EMX2OS EMX2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around EMX2OS on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the EMX2OS gene promoter:
  • E2F
  • CHOP-10
  • E2F-1
  • E2F-2
  • E2F-3a
  • E2F-4
  • E2F-5
  • C/EBPalpha
  • Ik-1
  • GATA-1

Genomic Locations for EMX2OS Gene

Genomic Locations for EMX2OS Gene
chr10:117,473,215-117,545,068
(GRCh38/hg38)
Size:
71,854 bases
Orientation:
Minus strand
chr10:119,232,726-119,304,579
(GRCh37/hg19)
Size:
71,854 bases
Orientation:
Minus strand

Genomic View for EMX2OS Gene

Genes around EMX2OS on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
EMX2OS Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for EMX2OS Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for EMX2OS Gene

Proteins for EMX2OS Gene

Post-translational modifications for EMX2OS Gene

No Post-translational modifications

No data available for DME Specific Peptides for EMX2OS Gene

Domains & Families for EMX2OS Gene

Gene Families for EMX2OS Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with EMX2OS: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for EMX2OS Gene

Function for EMX2OS Gene

Phenotypes From GWAS Catalog for EMX2OS Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for EMX2OS Gene

Localization for EMX2OS Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for EMX2OS Gene

Pathways & Interactions for EMX2OS Gene

SuperPathways for EMX2OS Gene

No Data Available

Interacting Proteins for EMX2OS Gene

Gene Ontology (GO) - Biological Process for EMX2OS Gene

None

No data available for Pathways by source and SIGNOR curated interactions for EMX2OS Gene

Drugs & Compounds for EMX2OS Gene

No Compound Related Data Available

Transcripts for EMX2OS Gene

mRNA/cDNA for EMX2OS Gene

(6) Additional mRNA sequences :
(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(9) RNA Central transcripts :

Unigene Clusters for EMX2OS Gene

EMX2 opposite strand/antisense RNA:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for EMX2OS Gene

No ASD Table

Relevant External Links for EMX2OS Gene

GeneLoc Exon Structure for
EMX2OS
ECgene alternative splicing isoforms for
EMX2OS

Expression for EMX2OS Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for EMX2OS Gene

mRNA differential expression in normal tissues according to GTEx for EMX2OS Gene

This gene is overexpressed in Uterus (x5.2) and Kidney - Cortex (x4.3).

NURSA nuclear receptor signaling pathways regulating expression of EMX2OS Gene:

EMX2OS

SOURCE GeneReport for Unigene cluster for EMX2OS Gene:

Hs.312592
genes like me logo Genes that share expression patterns with EMX2OS: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for EMX2OS Gene

Orthologs for EMX2OS Gene

Evolution for EMX2OS Gene

ENSEMBL:
Gene Tree for EMX2OS (if available)
TreeFam:
Gene Tree for EMX2OS (if available)

No data available for Orthologs for EMX2OS Gene

Paralogs for EMX2OS Gene

No data available for Paralogs for EMX2OS Gene

Variants for EMX2OS Gene

Sequence variations from dbSNP and Humsavar for EMX2OS Gene

SNP ID Clin Chr 10 pos Variation AA Info Type
rs756693906 conflicting-interpretations-of-pathogenicity, uncertain-significance, not specified 117,543,427(-) GCCGCCGCCGCCGCCGCCG/GCCGCCGCCGCCG/GCCGCCGCCGCCGCCG/GCCGCCGCCGCCGCCGCCGCCG/GCCGCCGCCGCCGCCGCCGCCGCCG intron_variant
rs373030604 likely-benign, not specified 117,543,372(-) A/T intron_variant
rs773003342 uncertain-significance, not specified 117,545,800(-) G/C upstream_transcript_variant
rs1000102286 -- 117,507,664(-) A/G intron_variant
rs1000103340 -- 117,547,008(-) GGGGGG/GGGGG upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for EMX2OS Gene

Variant ID Type Subtype PubMed ID
esv1009503 CNV loss 20482838
esv2741384 CNV deletion 23290073
nsv1045212 CNV gain 25217958
nsv1069966 CNV deletion 25765185
nsv474920 CNV novel sequence insertion 20440878
nsv509367 CNV insertion 20534489
nsv520464 CNV loss 19592680
nsv825579 CNV gain 20364138
nsv832003 CNV loss 17160897
nsv951857 CNV deletion 24416366

Additional Variant Information for EMX2OS Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
EMX2OS

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for EMX2OS Gene

Disorders for EMX2OS Gene

MalaCards: The human disease database

(1) MalaCards diseases for EMX2OS Gene - From: LncRNADisease

Disorder Aliases PubMed IDs
hypertension, essential
  • eht
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for EMX2OS

genes like me logo Genes that share disorders with EMX2OS: view

No data available for UniProtKB/Swiss-Prot and Genatlas for EMX2OS Gene

Publications for EMX2OS Gene

  1. Antisense transcripts at the EMX2 locus in human and mouse. (PMID: 12573261) Noonan FC … Simon TC (Genomics 2003) 2 3 22 58
  2. Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects. (PMID: 24324551) Deng X … REDSII Chagas Study Group from the NHLBI Retrovirus Epidemiology Donor Study-II Component International (PloS one 2013) 3 58
  3. lncRNAdb: a reference database for long noncoding RNAs. (PMID: 21112873) Amaral PP … Mattick JS (Nucleic acids research 2011) 3 58
  4. Regulation of Emx2 expression by antisense transcripts in murine cortico-cerebral precursors. (PMID: 20066053) Spigoni G … Mallamaci A (PloS one 2010) 3 58
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for EMX2OS Gene

Sources for EMX2OS Gene

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