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The protein encoded by this gene belongs to the PMP-22/EMP/MP20 family of proteins. The protein contains four transmembrane domains and two N-linked glycosylation sites. It is thought to be involved in cell proliferation, cell-cell interactions and function as a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] See more...
Aliases for EMP3 Gene
Aliases for EMP3 Gene
External Ids for EMP3 Gene
- HGNC: 3335
- Entrez Gene: 2014
- Ensembl: ENSG00000142227
- OMIM: 602335
- UniProtKB: P54852
Previous GeneCards Identifiers for EMP3 Gene
- GC19P049473
- GC19P049196
- GC19P053504
- GC19P053520
- GC19P048829
- GC19P045209
Summaries for EMP3 Gene
-
The protein encoded by this gene belongs to the PMP-22/EMP/MP20 family of proteins. The protein contains four transmembrane domains and two N-linked glycosylation sites. It is thought to be involved in cell proliferation, cell-cell interactions and function as a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
GeneCards Summary for EMP3 Gene
EMP3 (Epithelial Membrane Protein 3) is a Protein Coding gene. Diseases associated with EMP3 include Charcot-Marie-Tooth Disease, Axonal, Type 2B2 and Subglottis Neoplasm. An important paralog of this gene is PMP22.
UniProtKB/Swiss-Prot Summary for EMP3 Gene
-
Probably involved in cell proliferation and cell-cell interactions.
Additional gene information for EMP3 Gene
- HGNC(3335)
- Entrez Gene(2014)
- Ensembl(ENSG00000142227)
- OMIM(602335)
- UniProtKB(P54852)
- Open Targets Platform(ENSG00000142227)
- Search for EMP3 at DataMed
- Search for EMP3 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for EMP3 Gene
Genomics for EMP3 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for EMP3 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around EMP3 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for EMP3
- Top Transcription factor binding sites by QIAGEN in the EMP3 gene promoter:
-
- AREB6
- Bach2
- COUP-TF
- COUP-TF1
- E47
- HEN1
- HNF-4alpha1
- RelA
- RORalpha1
- STAT1
Genomic Locations for EMP3 Gene
Genomic Locations for EMP3 Gene
- chr19:48,321,509-48,330,554
- (GRCh38/hg38)
- Size:
- 9,046 bases
- Orientation:
- Plus strand
- chr19:48,824,766-48,833,810
- (GRCh37/hg19)
- Size:
- 9,045 bases
- Orientation:
- Plus strand
Genomic View for EMP3 Gene
Genes around EMP3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.33 by HGNC
- 19q13.33 by Entrez Gene
- 19q13.33 by Ensembl
EMP3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for EMP3 Gene
Proteins for EMP3 Gene
-
Protein details for EMP3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P54852-EMP3_HUMAN
- Recommended name:
- Epithelial membrane protein 3
- Protein Accession:
- P54852
- Q6FH01
Protein attributes for EMP3 Gene
- Size:
- 163 amino acids
- Molecular mass:
- 18429 Da
- Quaternary structure:
- No Data Available
Protein Expression for EMP3 Gene
Post-translational modifications for EMP3 Gene
Other Protein References for EMP3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for EMP3
- Novus Biologicals Antibodies for EMP3
-
Abcam antibodies for EMP3
- Invitrogen Antibodies for EMP3 (AFLGC-EMP3)
-
Santa Cruz Biotechnology (SCBT) Antibodies for EMP3
Protein Products
-
OriGene Purified Proteins for EMP3
- Search Origene for MassSpec and Protein Over-expression Lysates for EMP3
- Origene Custom Protein Services for EMP3
- antibodies-online: Show 7 available EMP3 Proteins ranked by validation data
- Compare Top EMP3 Proteins
-
Quality Products:
-
Abcam proteins for EMP3
Assay Products
- antibodies-online: Show 9 available EMP3 Elisa Kits ranked by validation data
- Compare Top EMP3 Elisa Kits
-
Quality Products:
-
Signalway ELISA kits for EMP3
No data available for DME Specific Peptides for EMP3 Gene
Domains & Families for EMP3 Gene
Gene Families for EMP3 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Predicted membrane proteins
Protein Domains for EMP3 Gene
- InterPro:
- Blocks:
-
- PMP-22/EMP/MP20 family
- Epithelial membrane protein EMP-3 signature
- ProtoNet:
Suggested Antigen Peptide Sequences for EMP3 Gene
- GenScript: Design optimal peptide antigens:
-
- Protein YMP (EMP3_HUMAN)
- EMP3 protein (Q6IBD3_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P54852- Family:
-
- Belongs to the PMP-22/EMP/MP20 family.
Function for EMP3 Gene
Molecular function for EMP3 Gene
- UniProtKB/Swiss-Prot Function:
- Probably involved in cell proliferation and cell-cell interactions.
- GENATLAS Biochemistry:
- epithelial membrane protein 3
Phenotypes From GWAS Catalog for EMP3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 12107182 |
Phenotypes for EMP3 Gene
- MGI mutant phenotypes for EMP3:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for EMP3:
Animal Models for EMP3 Gene
- MGI Knock Outs for EMP3:
-
- Emp3 Emp3<tm1378Arte>
Animal Model Products
-
Taconic Biosciences Mouse Models for EMP3
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for EMP3 - Select products 50% OFF >
- * EMP3 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for EMP3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for EMP3
-
Santa Cruz Biotechnology (SCBT) CRISPR for EMP3
miRNA for EMP3 Gene
- miRTarBase miRNAs that target EMP3
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for EMP3
- Browse OriGene Inhibitory RNA Products For EMP3
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Clone Products
- Applied Biological Materials (abm): Clones for EMP3 - Select products 50% OFF >
- * EMP3 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for EMP3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for EMP3
Cell Line Products
-
Horizon Cell Lines for EMP3
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for EMP3 Gene
Localization for EMP3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for EMP3 Gene
- Membrane. Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| nucleus | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| cytosol | 1 |
- Plasma membrane (2)
- Vesicles (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005886 | plasma membrane | IBA,IDA | 12107182 |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for EMP3 Gene
Interacting Proteins for EMP3 Gene
Selected Interacting proteins:
P54852-EMP3_HUMAN
ENSP00000270221
for EMP3 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for EMP3
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0008219 | cell death | IDA | 12107182 |
| GO:0032060 | bleb assembly | IDA | 12107182 |
No data available for Pathways by source and SIGNOR curated interactions for EMP3 Gene
Transcripts for EMP3 Gene
mRNA/cDNA for EMP3 Gene
- 2 REFSEQ mRNAs :
- 8 NCBI additional mRNA sequence :
- 9 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000599704 753 nts (view in UCSC)
- ENST00000270221 649 nts (view in UCSC)
- ENST00000596315 761 nts (view in UCSC)
- ENST00000594198 263 nts (view in UCSC)
- ENST00000597529 437 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for EMP3 - Select products 50% OFF >
- * EMP3 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for EMP3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for EMP3
-
Santa Cruz Biotechnology (SCBT) CRISPR for EMP3
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for EMP3
- Browse OriGene Inhibitory RNA Products For EMP3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for EMP3
Clone Products
- Applied Biological Materials (abm): Clones for EMP3 - Select products 50% OFF >
- * EMP3 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for EMP3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for EMP3
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c | · | 4d | ^ | 5 | ^ | 6a | · | 6b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | ||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||
| SP3: | - | - | |||||||||||||||||||||
| SP4: | - | - | - | - | |||||||||||||||||||
| SP5: | - | - | - | ||||||||||||||||||||
| SP6: | - | ||||||||||||||||||||||
| SP7: | - | - | - | - | - | - |
Relevant External Links for EMP3 Gene
- GeneLoc Exon Structure for
- EMP3
Expression for EMP3 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Bone (Muscoskeletal System)
- Inner Cell Mass (Early Embryonic Tissues)
-
Blood (Hematopoietic System)
- Hematopoietic Stem Cells Hematopoietic Bone Marrow
- Gut Tube (Gastrointestinal Tract)
- Heart (Cardiovascular System)
- Limb (Muscoskeletal System)
- Cartilage (Muscoskeletal System)
-
Spleen (Hematopoietic System)
-
Gall Bladder (Hepatobiliary System)
-
Lung (Respiratory System)
-
Ovary (Reproductive System)
mRNA differential expression in normal tissues according to GTEx for EMP3 Gene
This gene is overexpressed in Whole Blood (x9.7).
This gene is overexpressed in Colon (11.1) and Esophagus (9.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for EMP3 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for EMP3
SOURCE GeneReport for Unigene cluster for EMP3 Gene:
Hs.9999Evidence on tissue expression from TISSUES for EMP3 Gene
- Lung(4.4)
- Spleen(4.4)
- Nervous system(2.9)
- Skin(2.7)
- Intestine(2.7)
- Heart(2.5)
- Blood(2.3)
- Stomach(2.2)
- Muscle(2.2)
- Lymph node(2.1)
- Kidney(2.1)
Primer Products
-
OriGene qPCR primer pairs for EMP3
-
OriGene qPCR primer pairs and template standards for EMP3
Gene Expression Assay Products
No data available for Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for EMP3 Gene
Orthologs for EMP3 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | EMP3 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | EMP3 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | EMP3 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Emp3 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Emp3 30 |
|
||
| Lizard (Anolis carolinensis) |
Reptilia | EMP3 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | emp3 30 |
|
||
| Str.8279 30 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | emp3-prov 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | zgc:114127 30 |
|
||
| EMP3 (2 of 2) 31 |
|
OneToMany | |||
| EMP3 (1 of 2) 31 |
|
OneToMany |
- Species where no ortholog for EMP3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for EMP3 Gene
- ENSEMBL:
- Gene Tree for EMP3 (if available)
- TreeFam:
- Gene Tree for EMP3 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for EMP3: view image
Paralogs for EMP3 Gene
Paralogs for EMP3 Gene
(3) SIMAP similar genes for EMP3 Gene using alignment to 7 proteins:
- EMP3_HUMAN
- M0QXN1_HUMAN
- M0QXS0_HUMAN
- M0QZ66_HUMAN
- M0R122_HUMAN
- M0R1L9_HUMAN
- Q6IBD3_HUMAN
Variants for EMP3 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for EMP3 Gene
| SNP ID | Clinical significance and condition | Chr 19 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs4893 | - | p.Ile125Val |
Residual Variation Intolerance Score:
69% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.51;
43.88% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for EMP3 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- EMP3
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for EMP3 Gene
Disorders for EMP3 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| charcot-marie-tooth disease, axonal, type 2b2 |
|
|
| subglottis neoplasm |
|
|
| adult oligodendroglioma |
|
|
| charcot-marie-tooth disease |
|
|
| giant cell glioblastoma |
|
|
Search EMP3 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for EMP3
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for EMP3 Gene
Publications for EMP3 Gene
- Analysis of candidate genes for prostate cancer. (PMID: 15583422) Burmester JK … Catalona WJ (Human heredity 2004) 3 23 41
- HNMP-1: a novel hematopoietic and neural membrane protein differentially regulated in neural development and injury. (PMID: 9204931) Bolin LM … McClanahan TK (The Journal of neuroscience : the official journal of the Society for Neuroscience 1997) 3 4 23
- Epithelial membrane protein-2 and epithelial membrane protein-3: two novel members of the peripheral myelin protein 22 gene family. (PMID: 8917086) Taylor V … Suter U (Gene 1996) 3 4 23
- Characterization of a tumor-associated gene, a member of a novel family of genes encoding membrane glycoproteins. (PMID: 8996089) Ben-Porath I … Benvenisty N (Gene 1996) 2 3 4
- EMP3 as a tumor suppressor gene for esophageal squamous cell carcinoma. (PMID: 18823699) Fumoto S … Nishiyama M (Cancer letters 2009) 3 23
ExternalLinks
Products for EMP3 Gene
- Custom Antibody ServicesOriGene Antibodies for EMP3
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for EMP3
- Search Origene for MassSpec and Protein Over-expression Lysates for EMP3
- Origene Custom Protein Services for EMP3
- Origene shrna, sirna, and RNAi products in human, mouse, rat for EMP3
- Browse OriGene Inhibitory RNA Products For EMP3
- OriGene qPCR primer pairs for EMP3
- OriGene qPCR primer pairs and template standards for EMP3
- OriGene CRISPR knockouts for EMP3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For EMP3
- Sino Biological Human cDNA Clone for EMP3
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- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for EMP3
- Novus Biologicals proteins and lysates for EMP3
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for EMP3
- Abcam proteins for EMP3
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Taconic Biosciences Mouse Models for EMP3
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for EMP3 (AFLGC-EMP3)
- VectorBuilder Custom and pre-made DNA vectors for EMP3 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for EMP3 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for EMP3 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for EMP3 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for EMP3
- antibodies-online: Show 17 available EMP3 Antibodies ranked by validation data
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- Quality Products:
- antibodies-online: Show 9 available EMP3 Elisa Kits ranked by validation data
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- Quality Products:
- antibodies-online: Show 7 available EMP3 Proteins ranked by validation data
- Compare Top EMP3 Proteins
- Quality Products:
- Santa Cruz Biotechnology (SCBT) Antibodies for EMP3
- Search Santa Cruz Biotechnology (SCBT) for EMP3 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for EMP3
- Horizon Cell Lines for EMP3
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for EMP3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for EMP3
- Search GeneCopoeia for miRNA 3'UTR Target clone products for EMP3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for EMP3
- Signalway ELISA kits for EMP3
Sources for EMP3 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB