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EML3 (EMAP Like 3) is a Protein Coding gene. Diseases associated with EML3 include Retinitis Pigmentosa. An important paralog of this gene is EML4.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005515 | protein binding | IPI | 30723163 |
GO:0008017 | microtubule binding | IBA | 21873635 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IDA | 18445686 |
GO:0005737 | cytoplasm | IEA,IDA | 18445686 |
GO:0005819 | spindle | IDA | 18445686 |
GO:0005856 | cytoskeleton | IEA | -- |
GO:0005874 | microtubule | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000226 | microtubule cytoskeleton organization | IBA | 21873635 |
GO:0007080 | mitotic metaphase plate congression | IMP | 18445686 |
GO:1901673 | regulation of mitotic spindle assembly | IMP | 30723163 |
ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | ^ | 16 | ^ | 17 | ^ | 18a | · | 18b | ^ | 19 | ^ | 20a | · | 20b | ^ |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
SP2: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
SP3: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
SP4: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
SP5: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
SP6: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
SP7: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP8: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP9: |
ExUns: | 21a | · | 21b | · | 21c | ^ | 22a | · | 22b |
---|---|---|---|---|---|---|---|---|---|
SP1: | - | ||||||||
SP2: | - | ||||||||
SP3: | |||||||||
SP4: | |||||||||
SP5: | |||||||||
SP6: | |||||||||
SP7: | |||||||||
SP8: | |||||||||
SP9: |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | EML3 30 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | EML3 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | EML3 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | EML3 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Eml3 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | LOC102551660 30 |
|
||
Oppossum (Monodelphis domestica) |
Mammalia | EML3 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | EML3 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | eml3 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | eml3 30 31 |
|
OneToOne | |
Fruit Fly (Drosophila melanogaster) |
Insecta | DCX-EMAP 31 |
|
OneToMany | |
Worm (Caenorhabditis elegans) |
Secernentea | elp-1 31 |
|
OneToMany |
SNP ID | Clinical significance and condition | Chr 11 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
879335 | Uncertain Significance: Retinitis pigmentosa | 62,612,740(-) |
C/T NM_153265.3(EML3):c.-283G>A |
FIVE_PRIME_UTR | |
879336 | Uncertain Significance: Retinitis pigmentosa | 62,612,755(-) |
G/A NM_153265.3(EML3):c.-298C>T |
FIVE_PRIME_UTR | |
rs34098002 | - |
p.Gln620Lys |
Disorder | Aliases | PubMed IDs |
---|---|---|
retinitis pigmentosa |
|
|