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Aliases for EMILIN2 Gene
Aliases for EMILIN2 Gene
External Ids for EMILIN2 Gene
- HGNC: 19881
- Entrez Gene: 84034
- Ensembl: ENSG00000132205
- OMIM: 608928
- UniProtKB: Q9BXX0
Previous GeneCards Identifiers for EMILIN2 Gene
- GC18P002836
- GC18P002837
Summaries for EMILIN2 Gene
GeneCards Summary for EMILIN2 Gene
EMILIN2 (Elastin Microfibril Interfacer 2) is a Protein Coding gene. Diseases associated with EMILIN2 include Porokeratosis. Gene Ontology (GO) annotations related to this gene include extracellular matrix constituent conferring elasticity. An important paralog of this gene is EMILIN1.
UniProtKB/Swiss-Prot Summary for EMILIN2 Gene
-
May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity.
Additional gene information for EMILIN2 Gene
- HGNC(19881)
- Entrez Gene(84034)
- Ensembl(ENSG00000132205)
- OMIM(608928)
- UniProtKB(Q9BXX0)
- Open Targets Platform(ENSG00000132205)
- Search for EMILIN2 at DataMed
- Search for EMILIN2 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for EMILIN2 Gene
Genomics for EMILIN2 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for EMILIN2 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH18J002846 | Promoter/Enhancer | 1.9 | EPDnew FANTOM5 Ensembl ENCODE dbSUPER | 639.3 | +0.7 | 695 | 3.8 | RNF2 PRDM10 ZNF629 ZNF512 IKZF1 ZNF692 JUND PRDM1 MTA2 ZIC2 | EMILIN2 piR-40110-292 LPIN2 | |
| GH18J002905 | Promoter/Enhancer | 2 | EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER | 600.2 | +59.4 | 59395 | 3.2 | HNRNPL GATAD2A TFE3 NFKBIZ POLR2A LARP7 ZIC2 RBFOX2 IKZF2 EZH2 | EMILIN2 LPIN2 piR-57204 piR-42641 | |
| GH18J002845 | Promoter/Enhancer | 0.9 | FANTOM5 Ensembl dbSUPER | 621 | -1.5 | -1532 | 0.3 | SPI1 EZH2 | EMILIN2 MN297520 SMCHD1 | |
| GH18J002847 | Enhancer | 0.4 | ENCODE dbSUPER | 600.7 | -1.7 | -1698 | 0 | SPI1 | EMILIN2 MN297520 SMCHD1 | |
| GH18J003177 | Enhancer | 1.2 | FANTOM5 ENCODE | 35.4 | +332.4 | 332352 | 3.7 | SP1 LEF1 POLR2A BACH1 JUND STAT3 ZNF143 RELA PKNOX1 ZNF24 | EMILIN2 TGIF1 MYOM1 ENSG00000252258 MYL12B LPIN2 ENSG00000265399 lnc-LPIN2-3 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around EMILIN2 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for EMILIN2
- Top Transcription factor binding sites by QIAGEN in the EMILIN2 gene promoter:
-
- Oct-B1
- oct-B2
- oct-B3
- POU2F1
- POU2F1a
- POU2F2
- POU2F2 (Oct-2.1)
- POU2F2B
- POU2F2C
Genomic Locations for EMILIN2 Gene
Genomic Locations for EMILIN2 Gene
- chr18:2,847,006-2,916,003
- (GRCh38/hg38)
- Size:
- 68,998 bases
- Orientation:
- Plus strand
- chr18:2,847,028-2,915,991
- (GRCh37/hg19)
- Size:
- 68,964 bases
- Orientation:
- Plus strand
Genomic View for EMILIN2 Gene
Genes around EMILIN2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 18p11.32-p11.31 by HGNC
- 18p11.32-p11.31 by Entrez Gene
- 18p11.32 by Ensembl
EMILIN2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for EMILIN2 Gene
Proteins for EMILIN2 Gene
-
Protein details for EMILIN2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9BXX0-EMIL2_HUMAN
- Recommended name:
- EMILIN-2
- Protein Accession:
- Q9BXX0
- B2RMY3
- Q8NBH3
- Q96JQ4
Protein attributes for EMILIN2 Gene
- Size:
- 1053 amino acids
- Molecular mass:
- 115687 Da
- Quaternary structure:
-
- Homotrimer associated through a moderately stable interaction of the C-terminal globular C1q domains, allowing the nucleation of the triple helix and then a further quaternary assembly to higher-order polymers via intermolecular disulfide bonds (By similarity). Interacts with EMILIN1.
Protein Expression for EMILIN2 Gene
Post-translational modifications for EMILIN2 Gene
Other Protein References for EMILIN2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Creative Diagnostics Anti-EMILIN2 monoclonal antibody, clone EML2001
- Creative Biolabs Recombinant Mouse Anti-Human EMILIN2 Antibody
-
Custom Antibody ServicesOriGene Antibodies for EMILIN2
- Novus Biologicals Antibodies for EMILIN2
- Invitrogen Antibodies for EMILIN2 (AFLGC-EMILIN2)
-
Santa Cruz Biotechnology (SCBT) Antibodies for EMILIN2
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for EMILIN2
- Origene Custom Protein Services for EMILIN2
- antibodies-online: Show 8 available EMILIN2 Proteins ranked by validation data
- Compare Top EMILIN2 Proteins
-
Quality Products:
-
Abcam proteins for EMILIN2
Assay Products
- antibodies-online: Show 16 available EMILIN2 Elisa Kits ranked by validation data
- Compare Top EMILIN2 Elisa Kits
-
Quality Products:
-
Signalway ELISA kits for EMILIN2
No data available for DME Specific Peptides for EMILIN2 Gene
Domains & Families for EMILIN2 Gene
Gene Families for EMILIN2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted secreted proteins
Protein Domains for EMILIN2 Gene
- InterPro:
- Blocks:
-
- Complement C1q protein
- EMI
- ProtoNet:
Suggested Antigen Peptide Sequences for EMILIN2 Gene
- GenScript: Design optimal peptide antigens:
-
- Protein FOAP-10 (EMIL2_HUMAN)
- EMILIN2 protein (Q8N5L1_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for EMILIN2 Gene
Function for EMILIN2 Gene
Molecular function for EMILIN2 Gene
- UniProtKB/Swiss-Prot Function:
- May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity.
Phenotypes From GWAS Catalog for EMILIN2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 11278945 |
| GO:0030023 | extracellular matrix constituent conferring elasticity | NAS,RCA | 25037231 |
Phenotypes for EMILIN2 Gene
- MGI mutant phenotypes for EMILIN2:
- inferred from 3 alleles
- GenomeRNAi human phenotypes for EMILIN2:
Animal Models for EMILIN2 Gene
- MGI Knock Outs for EMILIN2:
-
- Emilin2 Emilin2<tm1.2Jhp>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for EMILIN2 - Select products 50% OFF >
- * EMILIN2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for EMILIN2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for EMILIN2
-
Santa Cruz Biotechnology (SCBT) CRISPR for EMILIN2
miRNA for EMILIN2 Gene
- miRTarBase miRNAs that target EMILIN2
-
- mmu-miR-320-3p (MIRT006297)
- hsa-miR-665 (MIRT564389)
- hsa-miR-4459 (MIRT564390)
- hsa-miR-1273e (MIRT564391)
- hsa-miR-7160-5p (MIRT564392)
- hsa-miR-25-5p (MIRT564393)
- hsa-miR-658 (MIRT564394)
- hsa-miR-202-3p (MIRT564395)
- hsa-miR-4500 (MIRT564396)
- hsa-miR-98-5p (MIRT564397)
- hsa-miR-4458 (MIRT564398)
- hsa-let-7i-5p (MIRT564399)
- hsa-let-7g-5p (MIRT564400)
- hsa-let-7f-5p (MIRT564401)
- hsa-let-7e-5p (MIRT564402)
- hsa-let-7d-5p (MIRT564403)
- hsa-let-7c-5p (MIRT564404)
- hsa-let-7b-5p (MIRT564405)
- hsa-miR-6087 (MIRT564406)
- hsa-let-7a-5p (MIRT564407)
- hsa-miR-7162-3p (MIRT564408)
- hsa-miR-219b-3p (MIRT564409)
- hsa-miR-1247-3p (MIRT564410)
- hsa-miR-4478 (MIRT564411)
- hsa-miR-4419b (MIRT564412)
- hsa-miR-3929 (MIRT564413)
- hsa-miR-6888-5p (MIRT564414)
- hsa-miR-302f (MIRT564415)
- hsa-miR-6771-5p (MIRT681997)
- hsa-miR-6884-5p (MIRT681998)
- hsa-miR-485-5p (MIRT681999)
- hsa-miR-6746-5p (MIRT682000)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for EMILIN2
- Browse OriGene Inhibitory RNA Products For EMILIN2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for EMILIN2
Clone Products
- Applied Biological Materials (abm): Clones for EMILIN2 - Select products 50% OFF >
- * EMILIN2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for EMILIN2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for EMILIN2
Cell Line Products
-
Horizon Cell Lines for EMILIN2
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for EMILIN2 Gene
Localization for EMILIN2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for EMILIN2 Gene
- Secreted, extracellular space, extracellular matrix. Note=Found mainly at the interface between amorphous elastin and microfibrils.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| plasma membrane | 1 |
| mitochondrion | 1 |
| cytosol | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | IEA,IDA | 11278945 |
| GO:0005581 | collagen trimer | IEA | -- |
| GO:0062023 | collagen-containing extracellular matrix | HDA | 23658023 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for EMILIN2 Gene
Pathways & Interactions for EMILIN2 Gene
Interacting Proteins for EMILIN2 Gene
GPS-Prot Interaction Network for EMILIN2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007155 | cell adhesion | IEA | -- |
| GO:0008150 | biological_process | ND | -- |
No data available for Pathways by source and SIGNOR curated interactions for EMILIN2 Gene
Transcripts for EMILIN2 Gene
mRNA/cDNA for EMILIN2 Gene
- 1 REFSEQ mRNAs :
- 9 NCBI additional mRNA sequence :
- 3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000254528 5944 nts (view in UCSC)
- ENST00000308080 1544 nts (view in UCSC)
- ENST00000583776 775 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for EMILIN2 - Select products 50% OFF >
- * EMILIN2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for EMILIN2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for EMILIN2
-
Santa Cruz Biotechnology (SCBT) CRISPR for EMILIN2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for EMILIN2
- Browse OriGene Inhibitory RNA Products For EMILIN2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for EMILIN2
Clone Products
- Applied Biological Materials (abm): Clones for EMILIN2 - Select products 50% OFF >
- * EMILIN2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for EMILIN2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for EMILIN2
Relevant External Links for EMILIN2 Gene
- GeneLoc Exon Structure for
- EMILIN2
Expression for EMILIN2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Adipose (Muscoskeletal System)
- Visceral White Adipocytes Visceral White Adipose
- HyStem+BMP4-induced SM30 cells
- Inner Cell Mass (Early Embryonic Tissues)
- Bone (Muscoskeletal System)
- Cartilage (Muscoskeletal System)
-
Blood (Hematopoietic System)
- Monocytes Peripheral Blood
-
Brain (Nervous System)
- Myelinating Oligodendrocyte Cells Forebrain White Matter
-
Glial Cells
- Myelinating Oligodendrocyte Cells Forebrain White Matter
-
Heart (Cardiovascular System)
- Atrioventricular Canal Cells Atrioventricular Canal
-
Prostate (Endocrine System)
-
Thyroid (Endocrine System)
-
Dermis (Integumentary System)
mRNA differential expression in normal tissues according to GTEx for EMILIN2 Gene
This gene is overexpressed in Whole Blood (x11.4).
This gene is overexpressed in Testis (27.2), NK cells (8.5), Gallbladder (7.6), and Platelet (6.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for EMILIN2 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for EMILIN2
SOURCE GeneReport for Unigene cluster for EMILIN2 Gene:
Hs.532815mRNA Expression by UniProt/SwissProt for EMILIN2 Gene:
Q9BXX0-EMIL2_HUMAN
Tissue specificity:
Highest levels are present in fetal heart and adult lung. Intermediate levels in peripheral leukocytes, placenta, and spinal cord and low expression in fetal brain, spleen, thymus, and lung and in adult heart, aorta, testis, bone marrow, small intestine, thymus, lymph node, and appendix.
Evidence on tissue expression from TISSUES for EMILIN2 Gene
- Kidney(4.2)
- Liver(4.2)
- Adrenal gland(4.1)
- Heart(2.4)
Primer Products
-
OriGene qPCR primer pairs for EMILIN2
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for EMILIN2 Gene
Orthologs for EMILIN2 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | EMILIN2 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | EMILIN2 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | EMILIN2 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Emilin2 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Emilin2 30 17 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | EMILIN2 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | EMILIN2 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | EMILIN2 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
OneToMany | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | emilin2 30 |
|
||
| Str.11831 30 |
|
||||
| Zebrafish (Danio rerio) |
Actinopterygii | LOC100001725 30 |
|
||
| EMILIN2 (2 of 2) 31 |
|
OneToMany | |||
| emilin2a 31 |
|
OneToMany |
- Species where no ortholog for EMILIN2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for EMILIN2 Gene
- ENSEMBL:
- Gene Tree for EMILIN2 (if available)
- TreeFam:
- Gene Tree for EMILIN2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for EMILIN2: view image
Paralogs for EMILIN2 Gene
Variants for EMILIN2 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for EMILIN2 Gene
| SNP ID | Clinical significance and condition | Chr 18 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 710514 | Benign: not provided | 2,908,958(+) | C/T | MISSENSE_VARIANT | |
| 725645 | Benign: not provided | 2,891,375(+) | C/T | SYNONYMOUS_VARIANT | |
| 726118 | Likely Benign: not provided | 2,890,820(+) | G/A | SYNONYMOUS_VARIANT | |
| 726343 | Benign: not provided | 2,891,492(+) | A/G | SYNONYMOUS_VARIANT | |
| 743337 | Benign: not provided | 2,890,718(+) | G/A | SYNONYMOUS_VARIANT |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv1007840 | CNV | deletion | 20482838 |
| esv1259581 | CNV | deletion | 17803354 |
| esv2178988 | CNV | deletion | 18987734 |
| esv2716681 | CNV | deletion | 23290073 |
| esv2761986 | CNV | gain | 21179565 |
| esv3554962 | CNV | deletion | 23714750 |
| esv3641577 | CNV | loss | 21293372 |
| esv3641578 | CNV | loss | 21293372 |
| nsv1062247 | CNV | gain | 25217958 |
| nsv1112153 | CNV | deletion | 24896259 |
| nsv1138595 | CNV | deletion | 24896259 |
| nsv1143694 | CNV | deletion | 24896259 |
| nsv1149493 | CNV | deletion | 26484159 |
| nsv1152529 | CNV | duplication | 26484159 |
| nsv2189 | CNV | deletion | 18451855 |
| nsv482935 | CNV | loss | 15286789 |
| nsv576251 | CNV | gain | 21841781 |
| nsv576312 | CNV | loss | 21841781 |
Residual Variation Intolerance Score:
82.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
6.18;
75.91% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for EMILIN2 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for EMILIN2 Gene
Disorders for EMILIN2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| porokeratosis |
|
|
Search EMILIN2 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for EMILIN2
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for EMILIN2 Gene
Publications for EMILIN2 Gene
- Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey SD … DREAM investigators (Diabetes care 2010) 3 41
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 41
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- Isolation and characterization of EMILIN-2, a new component of the growing EMILINs family and a member of the EMI domain-containing superfamily. (PMID: 11278945) Doliana R … Colombatti A (The Journal of biological chemistry 2001) 3 4
- A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway. (PMID: 30561431) Van Quickelberghe E … Gevaert K (Scientific data 2018) 3
ExternalLinks
Products for EMILIN2 Gene
- Custom Antibody ServicesOriGene Antibodies for EMILIN2
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- High-throughput Antibody Production Service
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- antibodies-online: Show 12 available EMILIN2 Antibodies ranked by validation data
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- Quality Products:
- antibodies-online: Show 8 available EMILIN2 Proteins ranked by validation data
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- Quality Products:
- Santa Cruz Biotechnology (SCBT) Antibodies for EMILIN2
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- Santa Cruz Biotechnology (SCBT) CRISPR for EMILIN2
- Horizon Cell Lines for EMILIN2
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for EMILIN2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for EMILIN2
- Search GeneCopoeia for miRNA 3'UTR Target clone products for EMILIN2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for EMILIN2
- Signalway ELISA kits for EMILIN2
Sources for EMILIN2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
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- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
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- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
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- (53) PubMed
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- (55) TGDB
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- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
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- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
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- (110) Genetics Home Reference
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- (115) NCBI Bookshelf
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- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
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- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
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- (143) Applied Biosystems
- (144) GlyConnect
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- (146) GeneCopoeia
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- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB