External Ids for EMB Gene
Previous GeneCards Identifiers for EMB Gene
This gene encodes a transmembrane glycoprotein that is a member of the immunoglobulin superfamily. The encoded protein may be involved in cell growth and development by mediating interactions between the cell and extracellular matrix. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Jan 2009]
GeneCards Summary for EMB Gene
EMB (Embigin) is a Protein Coding gene. Diseases associated with EMB include Splenic Manifestation Of Leukemia and Thymus Lymphoma. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and MAPK-Erk Pathway. An important paralog of this gene is BSG.
UniProtKB/Swiss-Prot for EMB Gene
Plays a role in the outgrowth of motoneurons and in the formation of neuromuscular junctions. Following muscle denervation, promotes nerve terminal sprouting and the formation of additional acetylcholine receptor clusters at synaptic sites without affecting terminal Schwann cell number or morphology. Delays the retraction of terminal sprouts following re-innervation of denervated endplates. May play a role in targeting the monocarboxylate transporters SLC16A1 and SLC16A7 to the cell membrane (By similarity).