Aliases for ELOVL3 Gene
- ELOVL Fatty Acid Elongase 3 2 3 4 5
- Elongation Of Very Long Chain Fatty Acids (FEN1/Elo2, SUR4/Elo3, Yeast)-Like 3 2 3
- Elongation Of Very Long Chain Fatty Acids Protein 3 3 4
- Very Long Chain 3-Ketoacyl-CoA Synthase 3 3 4
- Very Long Chain 3-Oxoacyl-CoA Synthase 3 3 4
- Cold-Inducible Glycoprotein Of 30 KDa 3 4
External Ids for ELOVL3 Gene
Previous GeneCards Identifiers for ELOVL3 Gene
This gene encodes a protein that belongs to the GNS1/SUR4 family. Members of this family play a role in elongation of long chain fatty acids to provide precursors for synthesis of sphingolipids and ceramides. [provided by RefSeq, Jul 2013]
GeneCards Summary for ELOVL3 Gene
ELOVL3 (ELOVL Fatty Acid Elongase 3) is a Protein Coding gene. Diseases associated with ELOVL3 include Fetal Akinesia Deformation Sequence 1. Among its related pathways are alpha-linolenic (omega3) and linoleic (omega6) acid metabolism and Metabolism. Gene Ontology (GO) annotations related to this gene include transferase activity. An important paralog of this gene is ELOVL6.
UniProtKB/Swiss-Prot Summary for ELOVL3 Gene
Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated and unsaturated acyl-CoA substrates with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate in the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.