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Aliases for ELOA3C Gene

Aliases for ELOA3C Gene

  • Elongin A3 Family Member C 2 3 5
  • RNA Polymerase II Transcription Factor SIII Subunit A3-Like-1 3
  • Putative Elongin-A3 Member C 3
  • EloA3C 4

External Ids for ELOA3C Gene

Summaries for ELOA3C Gene

GeneCards Summary for ELOA3C Gene

ELOA3C (Elongin A3 Family Member C) is a Protein Coding gene. An important paralog of this gene is ELOA3.

UniProtKB/Swiss-Prot for ELOA3C Gene

  • SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).

Additional gene information for ELOA3C Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ELOA3C Gene

Genomics for ELOA3C Gene

Genomic Locations for ELOA3C Gene

Genomic Locations for ELOA3C Gene
chr18:46,968,695-46,969,912
(GRCh38/hg38)
Size:
1,218 bases
Orientation:
Minus strand

Genomic View for ELOA3C Gene

Genes around ELOA3C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ELOA3C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ELOA3C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ELOA3C Gene

No data available for GeneHancer (GH) Regulatory Elements for ELOA3C Gene

Proteins for ELOA3C Gene

  • Protein details for ELOA3C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A0A087WX78-ELB3C_HUMAN
    Recommended name:
    Putative elongin-A3 member C
    Protein Accession:
    A0A087WX78

    Protein attributes for ELOA3C Gene

    Size:
    387 amino acids
    Molecular mass:
    41674 Da
    Quaternary structure:
    • Heterotrimer of an A (ELOA3, ELOA2, ELOA3, ELOA3B, ELOA3C or ELOA3D), ELOB and ELOC subunit.

neXtProt entry for ELOA3C Gene

Post-translational modifications for ELOA3C Gene

No Post-translational modifications

Other Protein References for ELOA3C Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ELOA3C Gene

Domains & Families for ELOA3C Gene

Gene Families for ELOA3C Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ELOA3C Gene

Graphical View of Domain Structure for InterPro Entry

A0A087WX78

UniProtKB/Swiss-Prot:

ELB3C_HUMAN :
  • The BC-box, which mediates binding to the elongin BC complex, has the consensus sequence [APST]-L-x(3)-C-x(3)-[AILV].
Domain:
  • The BC-box, which mediates binding to the elongin BC complex, has the consensus sequence [APST]-L-x(3)-C-x(3)-[AILV].
genes like me logo Genes that share domains with ELOA3C: view

No data available for Suggested Antigen Peptide Sequences for ELOA3C Gene

Function for ELOA3C Gene

Molecular function for ELOA3C Gene

UniProtKB/Swiss-Prot Function:
SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ELOA3C Gene

Localization for ELOA3C Gene

Subcellular locations from UniProtKB/Swiss-Prot for ELOA3C Gene

Gene Ontology (GO) - Cellular Components for ELOA3C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0070449 elongin complex IEA --
genes like me logo Genes that share ontologies with ELOA3C: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for ELOA3C Gene

Pathways & Interactions for ELOA3C Gene

SuperPathways for ELOA3C Gene

No Data Available

Interacting Proteins for ELOA3C Gene

Gene Ontology (GO) - Biological Process for ELOA3C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006357 regulation of transcription by RNA polymerase II IEA --
genes like me logo Genes that share ontologies with ELOA3C: view

No data available for Pathways by source and SIGNOR curated interactions for ELOA3C Gene

Drugs & Compounds for ELOA3C Gene

No Compound Related Data Available

Transcripts for ELOA3C Gene

mRNA/cDNA for ELOA3C Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for ELOA3C Gene

No ASD Table

Relevant External Links for ELOA3C Gene

GeneLoc Exon Structure for
ELOA3C
ECgene alternative splicing isoforms for
ELOA3C

Expression for ELOA3C Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ELOA3C Gene

Orthologs for ELOA3C Gene

Evolution for ELOA3C Gene

ENSEMBL:
Gene Tree for ELOA3C (if available)
TreeFam:
Gene Tree for ELOA3C (if available)

No data available for Orthologs for ELOA3C Gene

Paralogs for ELOA3C Gene

Paralogs for ELOA3C Gene

genes like me logo Genes that share paralogs with ELOA3C: view

Variants for ELOA3C Gene

Sequence variations from dbSNP and Humsavar for ELOA3C Gene

SNP ID Clin Chr 18 pos Variation AA Info Type
rs112351123 -- 46,969,373(-) C/T coding_sequence_variant, synonymous_variant
rs142340842 -- 46,968,660(-) CCCCCC/CCCCCCC 3_prime_UTR_variant
rs142945452 -- 46,969,644(-) C/T coding_sequence_variant, missense_variant
rs149165550 -- 46,968,129(-) TTT/TTTT downstream_transcript_variant
rs151258432 -- 46,969,690(-) GGGG/GGGGG coding_sequence_variant, frameshift

Additional Variant Information for ELOA3C Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ELOA3C

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for ELOA3C Gene

Disorders for ELOA3C Gene

Additional Disease Information for ELOA3C

No disorders were found for ELOA3C Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ELOA3C Gene

Publications for ELOA3C Gene

  1. DNA sequence and analysis of human chromosome 18. (PMID: 16177791) Nusbaum C … Lander ES (Nature 2005) 3 4 58
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for ELOA3C Gene

Sources for ELOA3C Gene

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