Aliases for ELMOD2 Gene
External Ids for ELMOD2 Gene
Previous GeneCards Identifiers for ELMOD2 Gene
This gene encodes one of six engulfment and motility (ELMO) domain-containing proteins. This gene is thought to play a role in antiviral responses. Mutations in this gene may be involved in the cause of familial idiopathic pulmonary fibrosis. [provided by RefSeq, Sep 2010]
GeneCards Summary for ELMOD2 Gene
ELMOD2 (ELMO Domain Containing 2) is a Protein Coding gene. Diseases associated with ELMOD2 include Patent Foramen Ovale and Pulmonary Fibrosis, Idiopathic. Among its related pathways are Lung fibrosis. Gene Ontology (GO) annotations related to this gene include GTPase activator activity. An important paralog of this gene is ELMOD1.
UniProtKB/Swiss-Prot for ELMOD2 Gene
Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family. Regulates IFN-related antiviral responses.