Aliases for ELAPOR1 Gene
External Ids for ELAPOR1 Gene
Previous HGNC Symbols for ELAPOR1 Gene
Previous GeneCards Identifiers for ELAPOR1 Gene
Expression of this gene is induced by estrogen and the encoded protein has been characterized as a transmembrane protein. The encoded protein has been found in to correlate with survival in certain carcinomas (PMID: 21102415) and may be important for cellular response to stress (PMID: 21072319). Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012]
GeneCards Summary for ELAPOR1 Gene
ELAPOR1 (Endosome-Lysosome Associated Apoptosis And Autophagy Regulator 1) is a Protein Coding gene. Diseases associated with ELAPOR1 include Baastrup's Syndrome and Endometrial Serous Adenocarcinoma. An important paralog of this gene is ELAPOR2.
UniProtKB/Swiss-Prot Summary for ELAPOR1 Gene
May protect cells from cell death by inducing cytosolic vacuolization and upregulating the autophagy pathway (PubMed:21072319). May play a role in apoptosis and cell proliferation through its interaction with HSPA5 (PubMed:26045166).