Aliases for EIF5A2 Gene
External Ids for EIF5A2 Gene
Previous GeneCards Identifiers for EIF5A2 Gene
GeneCards Summary for EIF5A2 Gene
EIF5A2 (Eukaryotic Translation Initiation Factor 5A2) is a Protein Coding gene. Among its related pathways are Metabolism of proteins and Gamma carboxylation, hypusine formation and arylsulfatase activation. Gene Ontology (GO) annotations related to this gene include RNA binding and translation elongation factor activity. An important paralog of this gene is EIF5A.
UniProtKB/Swiss-Prot for EIF5A2 Gene
mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation (By similarity).