This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter. [provided by RefSeq, Nov 2009] See more...

Aliases for EIF2B5 Gene

Aliases for EIF2B5 Gene

  • Eukaryotic Translation Initiation Factor 2B Subunit Epsilon 2 3 5
  • Eukaryotic Translation Initiation Factor 2B, Subunit 5 Epsilon, 82kDa 2 3
  • Translation Initiation Factor EIF-2B Subunit Epsilon 3 4
  • EIF-2B GDP-GTP Exchange Factor Subunit Epsilon 3 4
  • EIF2Bepsilon 2 3
  • EIF-2B 2 3
  • Eukaryotic Translation Initiation Factor 2B, Subunit 5 (Epsilon, 82kD) 2
  • EIF2B5 5
  • EIF2BE 4
  • CACH 3
  • LVWM 3
  • CLE 3

External Ids for EIF2B5 Gene

Previous GeneCards Identifiers for EIF2B5 Gene

  • GC03P180769
  • GC03P184848
  • GC03P185255
  • GC03P185173
  • GC03P185335
  • GC03P183852
  • GC03P181260

Summaries for EIF2B5 Gene

Entrez Gene Summary for EIF2B5 Gene

  • This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter. [provided by RefSeq, Nov 2009]

GeneCards Summary for EIF2B5 Gene

EIF2B5 (Eukaryotic Translation Initiation Factor 2B Subunit Epsilon) is a Protein Coding gene. Diseases associated with EIF2B5 include Leukoencephalopathy With Vanishing White Matter and Leukodystrophy. Among its related pathways are Viral mRNA Translation and Beta-Adrenergic Signaling. Gene Ontology (GO) annotations related to this gene include binding and translation initiation factor activity. An important paralog of this gene is GMPPA.

UniProtKB/Swiss-Prot Summary for EIF2B5 Gene

  • Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.

Gene Wiki entry for EIF2B5 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for EIF2B5 Gene

Genomics for EIF2B5 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for EIF2B5 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around EIF2B5 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for EIF2B5

Top Transcription factor binding sites by QIAGEN in the EIF2B5 gene promoter:
  • AREB6
  • CREB
  • FAC1
  • HNF-4alpha1
  • HNF-4alpha2
  • LCR-F1
  • MyoD
  • POU2F1
  • POU2F1a
  • TBP

Genomic Locations for EIF2B5 Gene

Genomic Locations for EIF2B5 Gene
chr3:184,135,023-184,146,127
(GRCh38/hg38)
Size:
11,105 bases
Orientation:
Plus strand
chr3:183,852,810-184,402,546
(GRCh37/hg19)
Size:
549,737 bases
Orientation:
Plus strand

Genomic View for EIF2B5 Gene

Genes around EIF2B5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
EIF2B5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for EIF2B5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for EIF2B5 Gene

Proteins for EIF2B5 Gene

  • Protein details for EIF2B5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q13144-EI2BE_HUMAN
    Recommended name:
    Translation initiation factor eIF-2B subunit epsilon
    Protein Accession:
    Q13144
    Secondary Accessions:
    • Q541Z1
    • Q96D04

    Protein attributes for EIF2B5 Gene

    Size:
    721 amino acids
    Molecular mass:
    80380 Da
    Quaternary structure:
    • Complex of five different subunits; alpha, beta, gamma, delta and epsilon. Interacts with RGS2.

    Three dimensional structures from OCA and Proteopedia for EIF2B5 Gene

neXtProt entry for EIF2B5 Gene

Post-translational modifications for EIF2B5 Gene

  • Phosphorylated at Ser-544 by DYRK2; this is required for subsequent phosphorylation by GSK3B (By similarity). Phosphorylated on serine and threonine residues by GSK3B; phosphorylation inhibits its function.
  • Polyubiquitinated, probably by NEDD4.
  • Ubiquitination at Lys61, Lys103, Lys141, Lys217, Lys420, Lys481, and Lys493
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for EIF2B5 Gene

Domains & Families for EIF2B5 Gene

Gene Families for EIF2B5 Gene

Human Protein Atlas (HPA):
  • Disease related genes
  • Plasma proteins
  • Predicted intracellular proteins

Protein Domains for EIF2B5 Gene

InterPro:
Blocks:
  • eIF4-gamma/eIF5/eIF2-epsilon
  • Bacterial transferase hexapeptide repeat
ProtoNet:

Suggested Antigen Peptide Sequences for EIF2B5 Gene

GenScript: Design optimal peptide antigens:
  • eIF-2B GDP-GTP exchange factor subunit epsilon (EI2BE_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q13144

UniProtKB/Swiss-Prot:

EI2BE_HUMAN :
  • Belongs to the eIF-2B gamma/epsilon subunits family.
Family:
  • Belongs to the eIF-2B gamma/epsilon subunits family.
genes like me logo Genes that share domains with EIF2B5: view

Function for EIF2B5 Gene

Molecular function for EIF2B5 Gene

UniProtKB/Swiss-Prot Function:
Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
GENATLAS Biochemistry:
eukariotic translation initiation factor 2B,subunit 5,ubiquitously expressed (epsilon,82kDa)

Phenotypes From GWAS Catalog for EIF2B5 Gene

Gene Ontology (GO) - Molecular Function for EIF2B5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003743 translation initiation factor activity NAS 8688466
GO:0005085 guanyl-nucleotide exchange factor activity IEA,ISS --
GO:0005515 protein binding IEA,IPI 10481074
GO:0031369 translation initiation factor binding IEA,ISS --
genes like me logo Genes that share ontologies with EIF2B5: view
genes like me logo Genes that share phenotypes with EIF2B5: view

Human Phenotype Ontology for EIF2B5 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for EIF2B5 Gene

MGI Knock Outs for EIF2B5:
  • Eif2b5 Eif2b5<tm1a(EUCOMM)Wtsi>

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for EIF2B5

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for EIF2B5 Gene

Localization for EIF2B5 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for EIF2B5 gene
Compartment Confidence
nucleus 5
cytosol 4
mitochondrion 2
endoplasmic reticulum 2
plasma membrane 1
extracellular 1
cytoskeleton 1
peroxisome 1
lysosome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for EIF2B5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus ISS --
GO:0005737 cytoplasm IEA,IDA 11323413
GO:0005829 cytosol TAS --
GO:0005851 eukaryotic translation initiation factor 2B complex IEA,IDA 11323413
genes like me logo Genes that share ontologies with EIF2B5: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for EIF2B5 Gene

Pathways & Interactions for EIF2B5 Gene

PathCards logo

SuperPathways for EIF2B5 Gene

SuperPathway Contained pathways
1 Viral mRNA Translation
2 Regulation of lipid metabolism Insulin signaling-generic cascades
.59
.59
.47
3 NFAT and Cardiac Hypertrophy
.42
.37
4 Translation Factors
5 Translational Control
genes like me logo Genes that share pathways with EIF2B5: view

Pathways by source for EIF2B5 Gene

3 GeneGo (Thomson Reuters) pathways for EIF2B5 Gene
  • Regulation of lipid metabolism Insulin signaling-generic cascades
  • Translation Regulation of EIF2 activity
  • Translation Insulin regulation of translation
5 Qiagen pathways for EIF2B5 Gene
  • eIF2 Pathway
  • GSK3 Signaling
  • IGF1R Signaling
  • Insulin Receptor Pathway
  • Signaling Involved in Cardiac Hypertrophy
1 Cell Signaling Technology pathway for EIF2B5 Gene

Interacting Proteins for EIF2B5 Gene

SIGNOR curated interactions for EIF2B5 Gene

Is activated by:
Is inactivated by:
Other effect:

Gene Ontology (GO) - Biological Process for EIF2B5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001541 ovarian follicle development IMP 15507143
GO:0006412 translation IEA --
GO:0006413 translational initiation IEA,IDA 16289705
GO:0007568 aging IEA --
GO:0009408 response to heat IEA,TAS 12499492
genes like me logo Genes that share ontologies with EIF2B5: view

Drugs & Compounds for EIF2B5 Gene

(1) Drugs for EIF2B5 Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Guanosine triphosphate Experimental Pharma 0

(1) Additional Compounds for EIF2B5 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with EIF2B5: view

Transcripts for EIF2B5 Gene

mRNA/cDNA for EIF2B5 Gene

1 REFSEQ mRNAs :
11 NCBI additional mRNA sequence :
31 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for EIF2B5

Alternative Splicing Database (ASD) splice patterns (SP) for EIF2B5 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b · 2c ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8a · 8b ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13a · 13b ^
SP1: - - - - - - - -
SP2: - - - - - - -
SP3: - - - - - - -
SP4: - - -
SP5: -
SP6: - - - - - - - - -
SP7: -
SP8:
SP9: - - -
SP10:
SP11: - - - - - - - - - - - - - - - - - - -
SP12: - - - - -
SP13: - -
SP14:
SP15:
SP16: - - -
SP17:

ExUns: 14a · 14b ^ 15a · 15b · 15c · 15d ^ 16 ^ 17a · 17b ^ 18a · 18b ^ 19a · 19b · 19c ^ 20a · 20b ^ 21 ^ 22a · 22b · 22c · 22d
SP1: - - - - -
SP2: - -
SP3: - -
SP4:
SP5:
SP6:
SP7: -
SP8: - -
SP9:
SP10: -
SP11: - - -
SP12:
SP13: -
SP14: -
SP15:
SP16:
SP17:

Relevant External Links for EIF2B5 Gene

GeneLoc Exon Structure for
EIF2B5

Expression for EIF2B5 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for EIF2B5 Gene

Protein differential expression in normal tissues from HIPED for EIF2B5 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (7.9) and Bone (7.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for EIF2B5 Gene



Protein tissue co-expression partners for EIF2B5 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for EIF2B5

SOURCE GeneReport for Unigene cluster for EIF2B5 Gene:

Hs.283551

Evidence on tissue expression from TISSUES for EIF2B5 Gene

  • Nervous system(4.9)
  • Lung(4.5)
  • Blood(4.4)
  • Liver(4.4)
  • Skin(3.3)
  • Muscle(2.5)
  • Heart(2.2)
  • Kidney(2.1)

Phenotype-based relationships between genes and organs from Gene ORGANizer for EIF2B5 Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • endocrine
  • integumentary
  • nervous
  • reproductive
  • skeletal muscle
  • skeleton
Regions:
Head and neck:
  • brain
  • cerebellum
  • cranial nerve
  • eye
  • head
  • pituitary gland
  • skull
Thorax:
  • breast
Abdomen:
  • adrenal gland
Pelvis:
  • ovary
  • penis
  • prostate
  • testicle
  • uterus
  • vagina
  • vulva
Limb:
  • lower limb
General:
  • hair
  • peripheral nerve
  • peripheral nervous system
  • skin
  • spinal cord
genes like me logo Genes that share expression patterns with EIF2B5: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for EIF2B5 Gene

Orthologs for EIF2B5 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for EIF2B5 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia EIF2B5 30 31
  • 99.72 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia EIF2B5 30 31
  • 91.62 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia EIF2B5 30 31
  • 90.39 (n)
OneToOne
Mouse
(Mus musculus)
Mammalia Eif2b5 30 17 31
  • 87.43 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Eif2b5 30
  • 87.13 (n)
Platypus
(Ornithorhynchus anatinus)
Mammalia EIF2B5 31
  • 85 (a)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia EIF2B5 31
  • 81 (a)
OneToOne
Chicken
(Gallus gallus)
Aves EIF2B5 30 31
  • 72.65 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia EIF2B5 31
  • 72 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia eif2b5 30
  • 65.92 (n)
Str.15685 30
African clawed frog
(Xenopus laevis)
Amphibia Xl.8238 30
Zebrafish
(Danio rerio)
Actinopterygii eif2b5 30 31
  • 64.84 (n)
OneToMany
EIF2B5 (2 of 2) 31
  • 54 (a)
OneToMany
wufd14g07 30
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP000082 30
  • 49.04 (n)
Fruit Fly
(Drosophila melanogaster)
Insecta eIF2B-epsilon 30 31
  • 48.47 (n)
OneToOne
eIF2B-&egr; 32
  • 31 (a)
Worm
(Caenorhabditis elegans)
Secernentea D2085.3 31
  • 25 (a)
OneToOne
A. gosspyii yeast
(Eremothecium gossypii)
Saccharomycetes AGOS_AGL094W 30
  • 46.43 (n)
K. Lactis Yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0A04235g 30
  • 44.39 (n)
Baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes GCD6 30 31
  • 42.31 (n)
OneToOne
Thale Cress
(Arabidopsis thaliana)
eudicotyledons AT2G34970 30
  • 45.47 (n)
Rice
(Oryza sativa)
Liliopsida Os02g0812400 30
  • 46.97 (n)
Bread mold
(Neurospora crassa)
Ascomycetes NCU02414 30
  • 47.11 (n)
Fission Yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes tif225 30
  • 45.01 (n)
Sea Squirt
(Ciona savignyi)
Ascidiacea -- 31
  • 39 (a)
OneToOne
Species where no ortholog for EIF2B5 was found in the sources mined by GeneCards:
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)

Evolution for EIF2B5 Gene

ENSEMBL:
Gene Tree for EIF2B5 (if available)
TreeFam:
Gene Tree for EIF2B5 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for EIF2B5: view image

Paralogs for EIF2B5 Gene

Paralogs for EIF2B5 Gene

genes like me logo Genes that share paralogs with EIF2B5: view

Variants for EIF2B5 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for EIF2B5 Gene

SNP ID Clinical significance and condition Chr 03 pos Variation AA Info Type
666195 Pathogenic: Leukoencephalopathy with vanishing white matter; not provided 184,140,589(+) C/T MISSENSE_VARIANT
692118 Pathogenic: Leukoencephalopathy with vanishing white matter 184,137,636(+) C/T MISSENSE_VARIANT
692119 Pathogenic: Leukoencephalopathy with vanishing white matter 184,140,590(+) G/C MISSENSE_VARIANT
714236 Benign: not provided 184,144,094(+) C/A INTRON_VARIANT
716332 Conflicting Interpretations: Leukoencephalopathy with vanishing white matter; not provided 184,144,143(+) C/T SYNONYMOUS_VARIANT

Additional dbSNP identifiers (rs#s) for EIF2B5 Gene

Structural Variations from Database of Genomic Variants (DGV) for EIF2B5 Gene

Variant ID Type Subtype PubMed ID
nsv829812 CNV loss 17160897

Variation tolerance for EIF2B5 Gene

Residual Variation Intolerance Score: 12.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 12.30; 94.11% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for EIF2B5 Gene

Human Gene Mutation Database (HGMD)
EIF2B5
SNPedia medical, phenotypic, and genealogical associations of SNPs for
EIF2B5

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for EIF2B5 Gene

Disorders for EIF2B5 Gene

MalaCards: The human disease database

(9) MalaCards diseases for EIF2B5 Gene - From: UniProtKB/Swiss-Prot, OMIM, ClinVar, GTR, Orphanet, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
leukoencephalopathy with vanishing white matter
  • cle
leukodystrophy
  • leukodystrophies
dystonia
  • dystonic disease
mehmo syndrome
  • mehmo
childhood ataxia with central nervous system hypomyelination / vanishing white matter
  • leukoencephalopathy with vanishing white matter
- elite association - COSMIC cancer census association via MalaCards

UniProtKB/Swiss-Prot

EI2BE_HUMAN
  • Leukodystrophy with vanishing white matter (VWM) [MIM:603896]: A leukodystrophy that occurs mainly in children. Neurological signs include progressive cerebellar ataxia, spasticity, inconstant optic atrophy and relatively preserved mental abilities. The disease is chronic-progressive with, in most individuals, additional episodes of rapid deterioration following febrile infections or minor head trauma. While childhood onset is the most common form of the disorder, some severe forms are apparent at birth. A severe, early-onset form seen among the Cree and Chippewayan populations of Quebec and Manitoba is called Cree leukoencephalopathy. Milder forms may not become evident until adolescence or adulthood. Some females with milder forms of the disease who survive to adolescence exhibit ovarian dysfunction. This variant of the disorder is called ovarioleukodystrophy. {ECO:0000269 PubMed:11704758, ECO:0000269 PubMed:12325082, ECO:0000269 PubMed:12707859, ECO:0000269 PubMed:15776425, ECO:0000269 PubMed:19158808, ECO:0000269 PubMed:21484434}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Additional Disease Information for EIF2B5

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
genes like me logo Genes that share disorders with EIF2B5: view

No data available for Genatlas for EIF2B5 Gene

Publications for EIF2B5 Gene

  1. Arg113His mutation of vanishing white matter is not present in multiple sclerosis. (PMID: 17439913) Lucas M … Izquierdo G (Multiple sclerosis (Houndmills, Basingstoke, England) 2007) 3 23 41
  2. Cloning and characterization of cDNAs encoding the epsilon-subunit of eukaryotic initiation factor-2B from rabbit and human. (PMID: 8688466) Asuru AI … Matts RL (Biochimica et biophysica acta 1996) 2 3 4
  3. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey SD … DREAM investigators (Diabetes care 2010) 3 41
  4. A large-scale candidate gene association study of age at menarche and age at natural menopause. (PMID: 20734064) He C … Hunter DJ (Human genetics 2010) 3 41
  5. Genotype-phenotype correlation in vanishing white matter disease. (PMID: 20975056) van der Lei HD … van der Knaap MS (Neurology 2010) 3 41

Products for EIF2B5 Gene

Sources for EIF2B5 Gene