Aliases for EIF2B2 Gene
External Ids for EIF2B2 Gene
Previous GeneCards Identifiers for EIF2B2 Gene
This gene encodes the beta subunit of eukaryotic initiation factor-2B (EIF2B). EIF2B is involved in protein synthesis and exchanges GDP and GTP for its activation and deactivation. [provided by RefSeq, Aug 2011]
GeneCards Summary for EIF2B2 Gene
EIF2B2 (Eukaryotic Translation Initiation Factor 2B Subunit Beta) is a Protein Coding gene. Diseases associated with EIF2B2 include Leukoencephalopathy With Vanishing White Matter and Premature Ovarian Failure 1. Among its related pathways are Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling and Translation Factors. Gene Ontology (GO) annotations related to this gene include GTP binding and translation initiation factor activity. An important paralog of this gene is EIF2B4.
UniProtKB/Swiss-Prot Summary for EIF2B2 Gene
Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.