Aliases for EID2 Gene
External Ids for EID2 Gene
Previous HGNC Symbols for EID2 Gene
Previous GeneCards Identifiers for EID2 Gene
GeneCards Summary for EID2 Gene
EID2 (EP300 Interacting Inhibitor Of Differentiation 2) is a Protein Coding gene. Diseases associated with EID2 include Cutaneous Diphtheria and Epidemic Pleurodynia. Among its related pathways are TGF-beta Signaling Pathway (WikiPathways). Gene Ontology (GO) annotations related to this gene include SMAD binding. An important paralog of this gene is EID2B.
UniProtKB/Swiss-Prot Summary for EID2 Gene
Interacts with EP300 and acts as a repressor of MYOD-dependent transcription and muscle differentiation. Inhibits EP300 histone acetyltransferase activity. Acts as a repressor of TGFB/SMAD transcriptional responses. May act as a repressor of the TGFB/SMAD3-dependent signaling by selectively blocking formation of TGFB-induced SMAD3-SMAD4 complex.