Aliases for EHBP1 Gene
External Ids for EHBP1 Gene
Previous GeneCards Identifiers for EHBP1 Gene
This gene encodes an Eps15 homology domain binding protein. The encoded protein may play a role in endocytic trafficking. A single nucleotide polymorphism in this gene is associated with an aggressive form of prostate cancer. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
GeneCards Summary for EHBP1 Gene
EHBP1 (EH Domain Binding Protein 1) is a Protein Coding gene. Diseases associated with EHBP1 include Prostate Cancer, Hereditary, 12 and Bardet-Biedl Syndrome 7. An important paralog of this gene is EHBP1L1.
UniProtKB/Swiss-Prot Summary for EHBP1 Gene
May play a role in actin reorganization. Links clathrin-mediated endocytosis to the actin cytoskeleton. May act as Rab effector protein and play a role in vesicle trafficking (PubMed:14676205, PubMed:27552051). Required for perinuclear sorting and insulin-regulated recycling of SLC2A4/GLUT4 in adipocytes (By similarity).