Aliases for EGR3 Gene
External Ids for EGR3 Gene
Previous GeneCards Identifiers for EGR3 Gene
This gene encodes a transcriptional regulator that belongs to the EGR family of C2H2-type zinc-finger proteins. It is an immediate-early growth response gene which is induced by mitogenic stimulation. The protein encoded by this gene participates in the transcriptional regulation of genes in controling biological rhythm. It may also play a role in a wide variety of processes including muscle development, lymphocyte development, endothelial cell growth and migration, and neuronal development. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2010]
GeneCards Summary for EGR3 Gene
EGR3 (Early Growth Response 3) is a Protein Coding gene. Diseases associated with EGR3 include Bipolar I Disorder and Patella, Chondromalacia Of. Among its related pathways are Circadian rythm related genes and Calcineurin-regulated NFAT-dependent transcription in lymphocytes. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity. An important paralog of this gene is EGR2.
UniProtKB/Swiss-Prot Summary for EGR3 Gene
Probable transcription factor involved in muscle spindle development.