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Aliases for EGFR-AS1 Gene

Subcategory (RNA class) for EGFR-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

13

Aliases for EGFR-AS1 Gene

  • EGFR Antisense RNA 1 2 3 5

External Ids for EGFR-AS1 Gene

Previous GeneCards Identifiers for EGFR-AS1 Gene

  • GC07M055249

Summaries for EGFR-AS1 Gene

GeneCards Summary for EGFR-AS1 Gene

EGFR-AS1 (EGFR Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with EGFR-AS1 include Osteogenic Sarcoma and Hepatocellular Carcinoma.

Additional gene information for EGFR-AS1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for EGFR-AS1 Gene

Genomics for EGFR-AS1 Gene

GeneHancer (GH) Regulatory Elements for EGFR-AS1 Gene

Promoters and enhancers for EGFR-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07J055185 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 657.1 +1.2 1182 5.2 FOXA2 MLX ARID4B SIN3A DMAP1 ZNF48 ZNF548 FOS NFKBIZ MXD4 EGFR-AS1 SEC61G GC07P055075 EGFR
GH07J055124 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 11.5 +58.8 58808 11.3 PKNOX1 FOXA2 ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF48 ETS1 ZNF213 EGFR EGFR-AS1 SEC61G GC07P055075
GH07J055060 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 10.5 +118.7 118693 19.4 HDGF PKNOX1 CLOCK FOXA2 MLX ZFP64 ARID4B SIN3A FEZF1 DMAP1 EGFR EGFR-AS1 SEC61G GC07P055075
GH07J055080 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 11 +104.1 104081 8 ELF3 FOXA2 SMAD1 RB1 MLX STAT5A BMI1 YBX1 BATF RARA EGFR EGFR-AS1 GC07P055075
GH07J054994 Enhancer 1.3 FANTOM5 Ensembl ENCODE 10 +193.1 193068 1.9 PKNOX1 FOXA2 SIN3A BRCA1 TCF12 FOS ATF7 RUNX3 SMARCA4 ETV4 LOC105375284 EGFR EGFR-AS1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around EGFR-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for EGFR-AS1 Gene

Genomic Locations for EGFR-AS1 Gene
chr7:55,179,750-55,188,949
(GRCh38/hg38)
Size:
9,200 bases
Orientation:
Minus strand
chr7:55,247,443-55,256,648
(GRCh37/hg19)
Size:
9,206 bases
Orientation:
Minus strand

Genomic View for EGFR-AS1 Gene

Genes around EGFR-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
EGFR-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for EGFR-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for EGFR-AS1 Gene

Proteins for EGFR-AS1 Gene

Post-translational modifications for EGFR-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for EGFR-AS1 Gene

Domains & Families for EGFR-AS1 Gene

Gene Families for EGFR-AS1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with EGFR-AS1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for EGFR-AS1 Gene

Function for EGFR-AS1 Gene

Phenotypes From GWAS Catalog for EGFR-AS1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for EGFR-AS1 Gene

Localization for EGFR-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for EGFR-AS1 Gene

Pathways & Interactions for EGFR-AS1 Gene

SuperPathways for EGFR-AS1 Gene

No Data Available

Interacting Proteins for EGFR-AS1 Gene

Gene Ontology (GO) - Biological Process for EGFR-AS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for EGFR-AS1 Gene

Drugs & Compounds for EGFR-AS1 Gene

No Compound Related Data Available

Transcripts for EGFR-AS1 Gene

mRNA/cDNA for EGFR-AS1 Gene

(2) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(2) RNA Central transcripts :

Unigene Clusters for EGFR-AS1 Gene

EGFR antisense RNA 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for EGFR-AS1 Gene

No ASD Table

Relevant External Links for EGFR-AS1 Gene

GeneLoc Exon Structure for
EGFR-AS1
ECgene alternative splicing isoforms for
EGFR-AS1

Expression for EGFR-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for EGFR-AS1 Gene

SOURCE GeneReport for Unigene cluster for EGFR-AS1 Gene:

Hs.720489
genes like me logo Genes that share expression patterns with EGFR-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for EGFR-AS1 Gene

Orthologs for EGFR-AS1 Gene

Evolution for EGFR-AS1 Gene

ENSEMBL:
Gene Tree for EGFR-AS1 (if available)
TreeFam:
Gene Tree for EGFR-AS1 (if available)

No data available for Orthologs for EGFR-AS1 Gene

Paralogs for EGFR-AS1 Gene

No data available for Paralogs for EGFR-AS1 Gene

Variants for EGFR-AS1 Gene

Sequence variations from dbSNP and Humsavar for EGFR-AS1 Gene

SNP ID Clin Chr 07 pos Variation AA Info Type
rs1050171 benign, likely-benign, not specified, Lung cancer 55,181,370(-) G/A non_coding_transcript_variant
rs1057519861 not-provided, Non-small cell lung cancer 55,181,398(-) T/A non_coding_transcript_variant
rs121434569 protective, drug-response, conflicting-interpretations-of-pathogenicity, likely-pathogenic, Nonsmall cell lung cancer, resistance to tyrosine kinase inhibitor in, Tyrosine kinase inhibitor response, Non-small cell lung cancer, gefitinib response - Efficacy, erlotinib response - Efficacy, Lung cancer, EGFR-related lung cancer 55,181,378(-) C/T non_coding_transcript_variant
rs121913230 likely-pathogenic, Squamous cell carcinoma 55,181,437(-) G/A non_coding_transcript_variant
rs121913431 likely-pathogenic, Squamous cell carcinoma 55,181,438(-) G/A non_coding_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for EGFR-AS1 Gene

Variant ID Type Subtype PubMed ID
esv2734425 CNV deletion 23290073

Additional Variant Information for EGFR-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
EGFR-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for EGFR-AS1 Gene

Disorders for EGFR-AS1 Gene

MalaCards: The human disease database

(2) MalaCards diseases for EGFR-AS1 Gene - From: LncRNADisease and DISEASES

Disorder Aliases PubMed IDs
osteogenic sarcoma
  • osteosarcoma; osrc
hepatocellular carcinoma
  • hcc
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for EGFR-AS1

genes like me logo Genes that share disorders with EGFR-AS1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for EGFR-AS1 Gene

Publications for EGFR-AS1 Gene

  1. Long noncoding RNA EGFR-AS1 mediates epidermal growth factor receptor addiction and modulates treatment response in squamous cell carcinoma. (PMID: 28920960) Tan DSW … Iyer NG (Nature medicine 2017) 2 3 58
  2. The long noncoding RNA, EGFR-AS1, a target of GHR, increases the expression of EGFR in hepatocellular carcinoma. (PMID: 26271667) Qi HL … Liu ZS (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016) 2 3 58
  3. Generation and analysis of 280,000 human expressed sequence tags. (PMID: 8889549) Hillier LD … Marra M (Genome research 1996) 3 58

Products for EGFR-AS1 Gene

Sources for EGFR-AS1 Gene

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