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This gene encodes a member of the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of cell cycle, proliferation, and developmental processes. The gene product contains a signal peptide, suggesting that it is secreted; an EGF repeat region consisting of 4 c... See more...
Aliases for EGFL6 Gene
Aliases for EGFL6 Gene
External Ids for EGFL6 Gene
- HGNC: 3235
- Entrez Gene: 25975
- Ensembl: ENSG00000198759
- OMIM: 300239
- UniProtKB: Q8IUX8
Previous HGNC Symbols for EGFL6 Gene
- MAEG
Previous GeneCards Identifiers for EGFL6 Gene
- GC0XP012826
- GC0XP012407
- GC0XP012949
- GC0XP013347
- GC0XP013497
- GC0XP011346
Summaries for EGFL6 Gene
-
This gene encodes a member of the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of cell cycle, proliferation, and developmental processes. The gene product contains a signal peptide, suggesting that it is secreted; an EGF repeat region consisting of 4 complete EGF-like repeats and 1 partial EGF-like repeat, 3 of which have a calcium-binding consensus sequence; an arg-gly-asp integrin association motif; and a MAM domain, which is believed to have an adhesive function. This gene is expressed early during development, and its expression has been detected in lung and meningioma tumors. [provided by RefSeq, Jul 2008]
GeneCards Summary for EGFL6 Gene
EGFL6 (EGF Like Domain Multiple 6) is a Protein Coding gene. Diseases associated with EGFL6 include Benign Meningioma and Fibrous Meningioma. Gene Ontology (GO) annotations related to this gene include calcium ion binding and integrin binding. An important paralog of this gene is NPNT.
UniProtKB/Swiss-Prot Summary for EGFL6 Gene
-
May bind integrin alpha-8/beta-1 and play a role in hair follicle morphogenesis. Promotes matrix assembly (By similarity).
Additional gene information for EGFL6 Gene
- HGNC(3235)
- Entrez Gene(25975)
- Ensembl(ENSG00000198759)
- OMIM(300239)
- UniProtKB(Q8IUX8)
- Open Targets Platform(ENSG00000198759)
- Monarch Initiative
- Search for EGFL6 at DataMed
- Search for EGFL6 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for EGFL6 Gene
Genomics for EGFL6 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for EGFL6 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH0XJ013569 | Promoter | 0.4 | EPDnew | 600.7 | 0.0 | -19 | 0.1 | EZH2 | EGFL6 RF00994-1159 ATXN3L | |
| GH0XJ013555 | Promoter | 0.3 | EPDnew | 600.4 | -14.4 | -14353 | 0.1 | EGFL6 piR-57460-695 HSALNG0136713 ATXN3L | ||
| GH0XJ013519 | Enhancer | 0.3 | Ensembl ENCODE | 27.6 | -48.4 | -48389 | 2.4 | EGFL6 piR-57460-695 HSALNG0136713 ATXN3L | ||
| GH0XJ013522 | Enhancer | 0.5 | Ensembl ENCODE | 17.9 | -46.1 | -46084 | 1.4 | CTCF RAD21 | EGFL6 piR-57460-695 HSALNG0136713 ATXN3L | |
| GH0XJ013533 | Enhancer | 0.5 | Ensembl | 12.7 | -35.7 | -35700 | 0.6 | ZNF692 JUND CEBPB FOS JUN BHLHE40 USF2 | EGFL6 piR-57460-695 HSALNG0136713 ATXN3L |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around EGFL6 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for EGFL6
- Top Transcription factor binding sites by QIAGEN in the EGFL6 gene promoter:
-
- FOXD3
- FOXJ2
- Ik-1
- Max1
- p53
- POU3F2
- POU6F1 (c2)
- SRF
- SRF (504 AA)
- YY1
Genomic Locations for EGFL6 Gene
Genomic Locations for EGFL6 Gene
- chrX:13,569,601-13,633,575
- (GRCh38/hg38)
- Size:
- 63,975 bases
- Orientation:
- Plus strand
- chrX:13,587,694-13,651,694
- (GRCh37/hg19)
- Size:
- 64,001 bases
- Orientation:
- Plus strand
Genomic View for EGFL6 Gene
Genes around EGFL6 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- Xp22.2 by HGNC
- Xp22.2 by Entrez Gene
- Xp22.2 by Ensembl
EGFL6 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for EGFL6 Gene
Proteins for EGFL6 Gene
-
Protein details for EGFL6 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8IUX8-EGFL6_HUMAN
- Recommended name:
- Epidermal growth factor-like protein 6
- Protein Accession:
- Q8IUX8
- B2RCB1
- Q6UXJ1
- Q8NBV0
- Q8WYG3
- Q9NY67
- Q9NZL7
- Q9UFK6
Protein attributes for EGFL6 Gene
- Size:
- 553 amino acids
- Molecular mass:
- 61317 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=AAG22483.1; Type=Frameshift; Evidence={ECO:0000305}; Sequence=AAQ88699.1; Type=Frameshift; Evidence={ECO:0000305};
Protein Expression for EGFL6 Gene
Post-translational modifications for EGFL6 Gene
Other Protein References for EGFL6 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for EGFL6
- Invitrogen Antibodies for EGFL6 (AFLGC-EGFL6)
-
Biorbyt antibodies for EGFL6
-
Boster Bio Antibodies for EGFL6
- Sino Biological Antibodies for EGFL6
Protein Products
-
OriGene Purified Proteins for EGFL6
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- Origene Custom Protein Services for EGFL6
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- ProSpec Recombinant Proteins for EGFL6
- antibodies-online: Show 7 available EGFL6 Proteins ranked by validation data
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-
Quality Products:
Assay Products
- antibodies-online: Show 8 available EGFL6 Elisa Kits ranked by validation data
- Compare Top EGFL6 Elisa Kits
-
Quality Products:
-
Signalway ELISA kits for EGFL6
No data available for DME Specific Peptides for EGFL6 Gene
Domains & Families for EGFL6 Gene
Gene Families for EGFL6 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted secreted proteins
Protein Domains for EGFL6 Gene
- InterPro:
- Blocks:
-
- EGF-like calcium-binding
- MAM domain signature
- ProtoNet:
Suggested Antigen Peptide Sequences for EGFL6 Gene
- GenScript: Design optimal peptide antigens:
-
- MAM and EGF domains-containing gene protein (EGFL6_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q8IUX8- Family:
-
- Belongs to the nephronectin family.
Function for EGFL6 Gene
Molecular function for EGFL6 Gene
- UniProtKB/Swiss-Prot Function:
- May bind integrin alpha-8/beta-1 and play a role in hair follicle morphogenesis. Promotes matrix assembly (By similarity).
- GENATLAS Biochemistry:
- EGF-like-domain,multiple 6,similar to fibrillin,expressed in brain and lung tumor and in fetal tissues,potential marker of malignancies
Phenotypes From GWAS Catalog for EGFL6 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005178 | integrin binding | TAS,IEA | -- |
| GO:0005509 | calcium ion binding | IEA | -- |
Phenotypes for EGFL6 Gene
- MGI mutant phenotypes for EGFL6:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for EGFL6:
-
- no effect
- Decreased viability
- Strongly decreased CFP-tsO45G cell surface transport
- Inconclusive
- Increased shRNA abundance (Z-score > 2)
- Increased cell death in breast cancer cell lines (MCF10A, MDA-MB-435)
- Increased caspase activity
- Decreased shRNA abundance (Z-score < -2)
- Increased epidermal growth factor (EGF) endocytosis, increased transferrin (TF) endocytosis
- Increased mitotic delay (prometaphase or metaphase alignment problems, MAP), decreased viability (cell death)
Animal Model Products
-
Taconic Biosciences Mouse Models for EGFL6
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for EGFL6 - Select products 50% OFF >
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-
OriGene CRISPR knockouts for EGFL6
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for EGFL6
-
Santa Cruz Biotechnology (SCBT) CRISPR for EGFL6
miRNA for EGFL6 Gene
- miRTarBase miRNAs that target EGFL6
-
- mmu-miR-466l-5p (MIRT578937)
- mmu-miR-466d-5p (MIRT578938)
- mmu-miR-466k (MIRT578939)
- mmu-miR-466i-5p (MIRT578940)
- mmu-miR-142a-3p (MIRT578941)
- mmu-miR-297a-5p (MIRT591358)
- mmu-miR-297c-5p (MIRT591359)
- mmu-miR-297b-5p (MIRT591360)
- mmu-miR-1198-5p (MIRT591361)
- mmu-miR-511-3p (MIRT591362)
- mmu-miR-466e-5p (MIRT591363)
- mmu-miR-1187 (MIRT591364)
- mmu-miR-466p-5p (MIRT591365)
- mmu-miR-466a-5p (MIRT591366)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for EGFL6
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Clone Products
- Applied Biological Materials (abm): Clones for EGFL6 - Select products 50% OFF >
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- Sino Biological Human cDNA Clone for EGFL6
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Cell Line Products
- ESI BIO PureStem 7SMOO32, NCr-fac & Meso Progenitor for EGFL6
-
Horizon Cell Lines for EGFL6
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for EGFL6 Gene
Localization for EGFL6 Gene
Subcellular locations from UniProtKB/Swiss-Prot for EGFL6 Gene
- Secreted, extracellular space, extracellular matrix, basement membrane.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| plasma membrane | 3 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| nucleus | 1 |
| endoplasmic reticulum | 0 |
| golgi apparatus | 0 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | IEA | -- |
| GO:0005604 | basement membrane | IEA | -- |
| GO:0005615 | extracellular space | TAS | 10610727 |
| GO:0016020 | membrane | IEA | -- |
| GO:0031012 | extracellular matrix | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for EGFL6 Gene
Pathways & Interactions for EGFL6 Gene
Interacting Proteins for EGFL6 Gene
Selected Interacting proteins:
Q8IUX8-EGFL6_HUMAN
ENSP00000369976
for EGFL6 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for EGFL6
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007155 | cell adhesion | IEA | -- |
| GO:0007275 | multicellular organism development | IEA | -- |
| GO:0010811 | positive regulation of cell-substrate adhesion | IEA | -- |
| GO:0030154 | cell differentiation | IEA | -- |
| GO:0030198 | extracellular matrix organization | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for EGFL6 Gene
Transcripts for EGFL6 Gene
mRNA/cDNA for EGFL6 Gene
- 2 REFSEQ mRNAs :
- 12 NCBI additional mRNA sequence :
- 3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000361306 2403 nts (view in UCSC)
- ENST00000380602 2385 nts (view in UCSC)
- ENST00000473826 364 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for EGFL6 - Select products 50% OFF >
- * EGFL6 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for EGFL6
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for EGFL6
-
Santa Cruz Biotechnology (SCBT) CRISPR for EGFL6
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for EGFL6
- Browse OriGene Inhibitory RNA Products For EGFL6
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for EGFL6
Clone Products
- Applied Biological Materials (abm): Clones for EGFL6 - Select products 50% OFF >
- * EGFL6 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for EGFL6
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for EGFL6
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b | ^ | 14a | · | 14b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||||||||||||||||||||||
| SP2: | - | ||||||||||||||||||||||||||||||||||||||||
| SP3: | - | ||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||
| SP5: | |||||||||||||||||||||||||||||||||||||||||
| SP6: |
Relevant External Links for EGFL6 Gene
- GeneLoc Exon Structure for
- EGFL6
Expression for EGFL6 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Ovary (Reproductive System)
- Pre-Granulosa Cells Primordial Follicle
- Ovarian Mesenchymal Stroma Cells Ovary Interstitium
- NULL (Uncategorized)
-
Lung (Respiratory System)
- Basal Cells Trachea
-
Epithelial Cells
- Basal Cells Trachea
-
Hair (Integumentary System)
- Bulge Stem Cells Bulge
- Intermediate Mesoderm (Gastrulation Derivatives)
- Kidney (Urinary System)
- Bone (Muscoskeletal System)
- Mesoderm (Gastrulation Derivatives)
- Neural Crest (Gastrulation Derivatives)
- Trophoblast (Extraembryonic Tissues)
-
Placenta (Extraembryonic Tissues)
mRNA differential expression in normal tissues according to GTEx for EGFL6 Gene
This gene is overexpressed in Lung (x16.4) and Adipose - Subcutaneous (x15.7).
This gene is overexpressed in Liver (63.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for EGFL6 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for EGFL6
SOURCE GeneReport for Unigene cluster for EGFL6 Gene:
Hs.12844Evidence on tissue expression from TISSUES for EGFL6 Gene
- Nervous system(4.3)
Primer Products
-
OriGene qPCR primer pairs for EGFL6
-
OriGene qPCR primer pairs and template standards for EGFL6
Gene Expression Assay Products
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for EGFL6 Gene
Orthologs for EGFL6 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | EGFL6 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | EGFL6 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | EGFL6 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Egfl6 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Egfl6 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | EGFL6 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | EGFL6 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | EGFL6 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | EGFL6 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | egfl6 30 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | egfl6-prov 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | egfl6 30 |
|
||
| EGFL6 31 |
|
OneToOne | |||
| Worm (Caenorhabditis elegans) |
Secernentea | mua-3 31 |
|
OneToMany | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
- Species where no ortholog for EGFL6 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for EGFL6 Gene
- ENSEMBL:
- Gene Tree for EGFL6 (if available)
- TreeFam:
- Gene Tree for EGFL6 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for EGFL6: view image
Paralogs for EGFL6 Gene
Variants for EGFL6 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for EGFL6 Gene
| SNP ID | Clinical significance and condition | Chr 0X pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 711786 | Likely Benign: not provided | 13,600,001(+) | C/T | MISSENSE_VARIANT | |
| 712289 | Benign: not provided | 13,594,844(+) | G/A | MISSENSE_VARIANT | |
| 712290 | Benign: not provided | 13,603,406(+) | C/T | MISSENSE_VARIANT | |
| 777786 | Benign: not provided | 13,600,042(+) | C/T | SYNONYMOUS_VARIANT | |
| 780681 | Benign: not provided | 13,600,018(+) | A/G | SYNONYMOUS_VARIANT |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3576773 | CNV | gain | 25503493 |
Residual Variation Intolerance Score:
91.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
5.97;
74.70% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for EGFL6 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- EGFL6
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for EGFL6 Gene
Disorders for EGFL6 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| benign meningioma |
|
|
| fibrous meningioma |
|
|
| lipomatosis, multiple symmetric |
|
|
| secretory meningioma |
|
|
| detrusor sphincter dyssynergia |
|
|
Search EGFL6 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for EGFL6
No data available for UniProtKB/Swiss-Prot and Genatlas for EGFL6 Gene
Publications for EGFL6 Gene
- Cloning of a novel epidermal growth factor repeat containing gene EGFL6: expressed in tumor and fetal tissues. (PMID: 10610727) Yeung G … Ford JE (Genomics 1999) 2 3 4
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark HF … Gray A (Genome research 2003) 3 4
- Identification of a new EGF-repeat-containing gene from human Xp22: a candidate for developmental disorders. (PMID: 10777661) Buchner G … Franco B (Genomics 2000) 3 4
- A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
- Identification of genes with universally upregulated or downregulated expressions in colorectal cancer. (PMID: 30395690) Song K … Guo Z (Journal of gastroenterology and hepatology 2019) 3
ExternalLinks
Products for EGFL6 Gene
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- ProSpec Recombinant Proteins for EGFL6
- ESI BIO PureStem 7SMOO32, NCr-fac & Meso Progenitor for EGFL6
- Taconic Biosciences Mouse Models for EGFL6
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for EGFL6 (AFLGC-EGFL6)
- VectorBuilder Custom and pre-made DNA vectors for EGFL6 (ie. gene expression, shRNA knockdown, CRISPR)
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- antibodies-online: Show 37 available EGFL6 Antibodies ranked by validation data
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- antibodies-online: Show 7 available EGFL6 Proteins ranked by validation data
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- Browse Boster Bio ELISA Kits
- Biorbyt antibodies for EGFL6
- Signalway ELISA kits for EGFL6
Sources for EGFL6 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
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- (25) DrugBank
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- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
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- (60) Sino Biological
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- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
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- (115) NCBI Bookshelf
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- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB