Aliases for EFR3B Gene
External Ids for EFR3B Gene
Previous HGNC Symbols for EFR3B Gene
Previous GeneCards Identifiers for EFR3B Gene
GeneCards Summary for EFR3B Gene
EFR3B (EFR3 Homolog B) is a Protein Coding gene. Diseases associated with EFR3B include Gastrointestinal Defects And Immunodeficiency Syndrome and Hypomyelinating Leukoencephalopathy. Gene Ontology (GO) annotations related to this gene include binding. An important paralog of this gene is EFR3A.
UniProtKB/Swiss-Prot Summary for EFR3B Gene
Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane (PubMed:23229899, PubMed:25608530, PubMed:26571211). The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis (Probable). In the complex, EFR3B probably acts as the membrane-anchoring component (PubMed:23229899). Also involved in responsiveness to G-protein-coupled receptors; it is however unclear whether this role is direct or indirect (PubMed:25380825).