This gene encodes an EF-hand-containing calcium binding protein. The encoded protein likely plays a role in calcium homeostasis. Mutations in this gene have been associated with susceptibility to juvenile myoclonic epilepsy and juvenile absence epilepsy. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010] See more...

Aliases for EFHC1 Gene

Aliases for EFHC1 Gene

  • EF-Hand Domain Containing 1 2 3 5
  • Myoclonin-1 2 3 4
  • EF-Hand Domain (C-Terminal) Containing 1 2 3
  • EF-Hand Domain-Containing Protein 1 3 4
  • RIB72 2 3
  • POC9 2 3
  • Epilepsy, Juvenile Myoclonic 1 2
  • DJ304B14.2 3
  • FLJ10466 2
  • EFHC1 5
  • EJM1 3

External Ids for EFHC1 Gene

Previous HGNC Symbols for EFHC1 Gene

  • EJM1
  • EJM

Previous GeneCards Identifiers for EFHC1 Gene

  • GC00U991099
  • GC06U900420
  • GC06P052331
  • GC06P052393
  • GC06P052116
  • GC06P052284
  • GC06P052420

Summaries for EFHC1 Gene

Entrez Gene Summary for EFHC1 Gene

  • This gene encodes an EF-hand-containing calcium binding protein. The encoded protein likely plays a role in calcium homeostasis. Mutations in this gene have been associated with susceptibility to juvenile myoclonic epilepsy and juvenile absence epilepsy. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010]

GeneCards Summary for EFHC1 Gene

EFHC1 (EF-Hand Domain Containing 1) is a Protein Coding gene. Diseases associated with EFHC1 include Epilepsy, Myoclonic Juvenile and Epilepsy, Juvenile Absence 1. Gene Ontology (GO) annotations related to this gene include calcium ion binding and protein C-terminus binding. An important paralog of this gene is EFHC2.

UniProtKB/Swiss-Prot Summary for EFHC1 Gene

  • Microtubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for mitotic spindle organization (PubMed:19734894, PubMed:28370826). Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration (PubMed:22926142). May enhance calcium influx through CACNA1E and stimulate programmed cell death (PubMed:15258581).

Gene Wiki entry for EFHC1 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for EFHC1 Gene

Genomics for EFHC1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for EFHC1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06J052415 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 648 +56.9 56902 6.8 BRCA1 ARHGAP35 SP1 HNRNPL CREB1 GATAD2A CTCF TEAD4 PRDM10 ZNF629 EFHC1 lnc-MCM3-3 MCM3 TRAM2 PAQR8 piR-38214
GH06J052359 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 600.7 -0.2 -209 4.2 SP1 GATAD2A PRDM10 ZNF629 POLR2A BACH1 LARP7 PHF21A ZIC2 RBFOX2 PAQR8 EFHC1 lnc-MCM3-2 lnc-MCM3-3
GH06J052992 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 30.2 +632.8 632778 4.6 HNRNPL CREB1 GATAD2A CTCF PRDM10 ZNF629 LEF1 IKZF1 NFKBIZ KDM1A ENSG00000202198 GSTA4 MN298307 RN7SK X05490 EFHC1 MCM3 CILK1 GSTA3 RF00019-091
GH06J053054 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 22.6 +699.6 699644 15.5 SP1 GATAD2A CTCF HNRNPL PRDM10 ZNF629 TFE3 RFX1 SIX5 LEF1 CILK1 FBXO9 MCM3 EFHC1 TRAM2 GSTA3 piR-38352-469
GH06J052563 Promoter/Enhancer 2.5 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 21.2 +209.1 209096 14.5 CEBPG HNRNPL CREB1 GATAD2A CTCF TEAD4 ZNF629 IKZF1 NFKBIZ KDM1A TRAM2-AS1 TRAM2 EFHC1 MCM3 PAQR8 ENSG00000216775 piR-32285-080
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around EFHC1 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for EFHC1

Top Transcription factor binding sites by QIAGEN in the EFHC1 gene promoter:
  • AML1a
  • GR
  • GR-alpha
  • Nkx2-2
  • POU2F1
  • RFX1
  • STAT3
  • USF-1
  • USF1
  • ZIC2

Genomic Locations for EFHC1 Gene

Genomic Locations for EFHC1 Gene
chr6:52,362,123-52,529,886
(GRCh38/hg38)
Size:
167,764 bases
Orientation:
Plus strand
chr6:52,284,994-52,387,892
(GRCh37/hg19)
Size:
102,899 bases
Orientation:
Plus strand

Genomic View for EFHC1 Gene

Genes around EFHC1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
EFHC1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for EFHC1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for EFHC1 Gene

Proteins for EFHC1 Gene

  • Protein details for EFHC1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5JVL4-EFHC1_HUMAN
    Recommended name:
    EF-hand domain-containing protein 1
    Protein Accession:
    Q5JVL4
    Secondary Accessions:
    • B4DMU3
    • F5GZD8
    • Q5XKM4
    • Q6E1U7
    • Q6E1U8
    • Q8WUL2
    • Q9NVW6

    Protein attributes for EFHC1 Gene

    Size:
    640 amino acids
    Molecular mass:
    73990 Da
    Quaternary structure:
    • Interacts with the C-terminus of CACNA1E (PubMed:15258581). Interacts with alpha-tubulin (PubMed:19734894).
    Miscellaneous:
    • [Isoform 2]: May be due to intron retention.

    Alternative splice isoforms for EFHC1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for EFHC1 Gene

Post-translational modifications for EFHC1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for EFHC1 Gene

Domains & Families for EFHC1 Gene

Gene Families for EFHC1 Gene

HGNC:
Human Protein Atlas (HPA):
  • Disease related genes
  • Predicted intracellular proteins

Protein Domains for EFHC1 Gene

Suggested Antigen Peptide Sequences for EFHC1 Gene

GenScript: Design optimal peptide antigens:
  • EF-hand domain containing 1 (B2CKC5_HUMAN)
  • Myoclonin-1 (EFHC1_HUMAN)
genes like me logo Genes that share domains with EFHC1: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for EFHC1 Gene

Function for EFHC1 Gene

Molecular function for EFHC1 Gene

UniProtKB/Swiss-Prot Function:
Microtubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for mitotic spindle organization (PubMed:19734894, PubMed:28370826). Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration (PubMed:22926142). May enhance calcium influx through CACNA1E and stimulate programmed cell death (PubMed:15258581).

Phenotypes From GWAS Catalog for EFHC1 Gene

Gene Ontology (GO) - Molecular Function for EFHC1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005509 calcium ion binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0008022 protein C-terminus binding ISS --
GO:0043014 alpha-tubulin binding IBA,IDA 19734894
genes like me logo Genes that share ontologies with EFHC1: view
genes like me logo Genes that share phenotypes with EFHC1: view

Human Phenotype Ontology for EFHC1 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for EFHC1 Gene

MGI Knock Outs for EFHC1:

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for EFHC1

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for EFHC1 Gene

Localization for EFHC1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for EFHC1 Gene

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for EFHC1 gene
Compartment Confidence
cytoskeleton 5
plasma membrane 3
cytosol 2
extracellular 1
mitochondrion 1
peroxisome 1
nucleus 1
endoplasmic reticulum 1

Gene Ontology (GO) - Cellular Components for EFHC1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000922 spindle pole IEA,IDA 28370826
GO:0005737 cytoplasm IEA --
GO:0005813 centrosome IDA 22926142
GO:0005815 microtubule organizing center IEA --
GO:0005819 spindle IEA --
genes like me logo Genes that share ontologies with EFHC1: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for EFHC1 Gene

Pathways & Interactions for EFHC1 Gene

PathCards logo

SuperPathways for EFHC1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for EFHC1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000281 mitotic cytokinesis IBA,IMP 28370826
GO:0007052 mitotic spindle organization IBA,IMP 19734894
GO:0021795 cerebral cortex cell migration IMP 22926142
GO:0051302 regulation of cell division IMP 19734894
GO:0060285 cilium-dependent cell motility IBA 21873635
genes like me logo Genes that share ontologies with EFHC1: view

No data available for Pathways by source and SIGNOR curated interactions for EFHC1 Gene

Drugs & Compounds for EFHC1 Gene

(1) Drugs for EFHC1 Gene - From: HMDB and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Calcium Nutra 6556
genes like me logo Genes that share compounds with EFHC1: view

Transcripts for EFHC1 Gene

mRNA/cDNA for EFHC1 Gene

2 REFSEQ mRNAs :
14 NCBI additional mRNA sequence :
39 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for EFHC1

Alternative Splicing Database (ASD) splice patterns (SP) for EFHC1 Gene

No ASD Table

Relevant External Links for EFHC1 Gene

GeneLoc Exon Structure for
EFHC1

Expression for EFHC1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for EFHC1 Gene

Protein differential expression in normal tissues from HIPED for EFHC1 Gene

This gene is overexpressed in Plasma (40.0) and Testis (23.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for EFHC1 Gene



Protein tissue co-expression partners for EFHC1 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for EFHC1

SOURCE GeneReport for Unigene cluster for EFHC1 Gene:

Hs.403171

mRNA Expression by UniProt/SwissProt for EFHC1 Gene:

Q5JVL4-EFHC1_HUMAN
Tissue specificity: Widely expressed. Not detected in lymphocytes.

Evidence on tissue expression from TISSUES for EFHC1 Gene

  • Nervous system(4.8)
  • Kidney(4.4)
  • Lung(2.3)

Phenotype-based relationships between genes and organs from Gene ORGANizer for EFHC1 Gene

Germ Layers:
  • ectoderm
  • mesoderm
Systems:
  • nervous
  • skeletal muscle
Regions:
Head and neck:
  • brain
  • head
genes like me logo Genes that share expression patterns with EFHC1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for EFHC1 Gene

Orthologs for EFHC1 Gene

This gene was present in the common ancestor of animals.

Orthologs for EFHC1 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia EFHC1 30 31
  • 99.64 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia EFHC1 30 31
  • 89.11 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia EFHC1 30 31
  • 87.24 (n)
OneToOne
Mouse
(Mus musculus)
Mammalia Efhc1 30 17 31
  • 83.49 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Efhc1 30
  • 83.07 (n)
Oppossum
(Monodelphis domestica)
Mammalia EFHC1 31
  • 68 (a)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia EFHC1 31
  • 67 (a)
OneToOne
Chicken
(Gallus gallus)
Aves EFHC1 30 31
  • 67.24 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia EFHC1 31
  • 62 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia efhc1 30
  • 64.57 (n)
Str.9549 30
African clawed frog
(Xenopus laevis)
Amphibia Xl.11087 30
Zebrafish
(Danio rerio)
Actinopterygii efhc1 30 31
  • 55.6 (n)
OneToOne
zgc63931 30
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP003805 30
  • 48.58 (n)
Worm
(Caenorhabditis elegans)
Secernentea Y49A10A.1 31
  • 24 (a)
OneToOne
Sea Squirt
(Ciona savignyi)
Ascidiacea -- 31
  • 58 (a)
OneToOne
Species where no ortholog for EFHC1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)

Evolution for EFHC1 Gene

ENSEMBL:
Gene Tree for EFHC1 (if available)
TreeFam:
Gene Tree for EFHC1 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for EFHC1: view image

Paralogs for EFHC1 Gene

Paralogs for EFHC1 Gene

(1) SIMAP similar genes for EFHC1 Gene using alignment to 3 proteins:

  • EFHC1_HUMAN
  • B2CKC5_HUMAN
  • H7C4B1_HUMAN
genes like me logo Genes that share paralogs with EFHC1: view

Variants for EFHC1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for EFHC1 Gene

SNP ID Clinical significance and condition Chr 06 pos Variation AA Info Type
641875 Uncertain Significance: Epilepsy, juvenile absence, susceptibility to, 1; Juvenile myoclonic epilepsy 52,424,081(+) A/G MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT
641895 Uncertain Significance: Epilepsy, juvenile absence, susceptibility to, 1; Juvenile myoclonic epilepsy 52,479,095(+) C/T MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT
641921 Uncertain Significance: Epilepsy, juvenile absence, susceptibility to, 1; Juvenile myoclonic epilepsy 52,452,807(+) A/C MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT
644582 Uncertain Significance: Epilepsy, juvenile absence, susceptibility to, 1; Juvenile myoclonic epilepsy 52,479,695(+) G/A MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT
645721 Likely Benign: Typical absence seizures; Juvenile myoclonic epilepsy 52,420,464(+) G/T MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT

Additional dbSNP identifiers (rs#s) for EFHC1 Gene

Structural Variations from Database of Genomic Variants (DGV) for EFHC1 Gene

Variant ID Type Subtype PubMed ID
esv3341940 CNV insertion 20981092
esv3608996 CNV gain 21293372
nsv1025395 CNV gain 25217958
nsv472897 CNV novel sequence insertion 20440878
nsv517935 CNV loss 19592680
nsv522674 CNV loss 19592680

Variation tolerance for EFHC1 Gene

Residual Variation Intolerance Score: 88.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.40; 77.08% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for EFHC1 Gene

Human Gene Mutation Database (HGMD)
EFHC1
SNPedia medical, phenotypic, and genealogical associations of SNPs for
EFHC1

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for EFHC1 Gene

Disorders for EFHC1 Gene

MalaCards: The human disease database

(27) MalaCards diseases for EFHC1 Gene - From: UniProtKB/Swiss-Prot, OMIM, ClinVar, GTR, Orphanet, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
epilepsy, myoclonic juvenile
  • ejm
epilepsy, juvenile absence 1
  • epilepsy, juvenile absence, susceptibility to, 1
juvenile absence epilepsy
  • childhood absence epilepsy
epilepsy
  • epilepsy syndrome
adolescence-adult electroclinical syndrome
- elite association - COSMIC cancer census association via MalaCards
Search EFHC1 in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

EFHC1_HUMAN
  • Juvenile myoclonic epilepsy 1 (EJM1) [MIM:254770]: A subtype of idiopathic generalized epilepsy. Patients have afebrile seizures only, with onset in adolescence (rather than in childhood) and myoclonic jerks which usually occur after awakening and are triggered by sleep deprivation and fatigue. {ECO:0000269 PubMed:15258581, ECO:0000269 PubMed:17634063, ECO:0000269 PubMed:22690745, ECO:0000269 PubMed:22727576, ECO:0000269 PubMed:22926142, ECO:0000269 PubMed:28370826}. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.
  • Juvenile absence epilepsy 1 (JAE1) [MIM:607631]: A subtype of idiopathic generalized epilepsy characterized by onset occurring around puberty, absence seizures, generalized tonic-clonic seizures (GTCS), GTCS on awakening, and myoclonic seizures. {ECO:0000269 PubMed:17159113, ECO:0000305 PubMed:17159113}. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.
  • Note=Mutation Leu-229 may be a cause of intractable epilepsy of infancy. Affected individuals have seizures of multiple type, manifested as tonic, clonic, and myoclonic seizures in the neonatal period, and as tonic seizures activated frequently by sleep, and repeated frequent myoclonic seizures in later infancy. The seizures are unresponsive to numerous antiepileptic drugs, and infants die in the first years of life. Although heterozygosity for Leu-229 has been associated with relatively benign forms of epilepsy in adolescence, homozygosity for the same mutation has much more severe consequences. {ECO:0000269 PubMed:22690745}.

Additional Disease Information for EFHC1

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
genes like me logo Genes that share disorders with EFHC1: view

No data available for Genatlas for EFHC1 Gene

Publications for EFHC1 Gene

  1. Mutations in EFHC1 cause juvenile myoclonic epilepsy. (PMID: 15258581) Suzuki T … Yamakawa K (Nature genetics 2004) 2 3 4 41
  2. Mutational analysis of EFHC1 gene in Italian families with juvenile myoclonic epilepsy. (PMID: 17634063) Annesi F … Quattrone A (Epilepsia 2007) 3 4 23
  3. Mutations in the GABRA1 and EFHC1 genes are rare in familial juvenile myoclonic epilepsy. (PMID: 16839746) Ma S … Hedera P (Epilepsy research 2006) 3 23 41
  4. Microtubule-associated defects caused by EFHC1 mutations in juvenile myoclonic epilepsy. (PMID: 28370826) Raju PK … Anand A (Human mutation 2017) 3 4
  5. Mutations of EFHC1, linked to juvenile myoclonic epilepsy, disrupt radial and tangential migrations during brain development. (PMID: 22926142) de Nijs L … Lakaye B (Human molecular genetics 2012) 3 4

Products for EFHC1 Gene

Sources for EFHC1 Gene