This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by EF-2 kinase phosporylation. [provided by RefSeq, Jul 2008] See more...

Aliases for EEF2 Gene

Aliases for EEF2 Gene

  • Eukaryotic Translation Elongation Factor 2 2 3 5
  • Polypeptidyl-TRNA Translocase 2 3
  • Elongation Factor 2 3 4
  • EEF-2 2 3
  • EF-2 3 4
  • EF2 3 4
  • Epididymis Secretory Sperm Binding Protein 3
  • SCA26 3
  • EEF2 5

External Ids for EEF2 Gene

Previous HGNC Symbols for EEF2 Gene

  • EF2

Previous GeneCards Identifiers for EEF2 Gene

  • GC19M004066
  • GC19M003916
  • GC19M003927
  • GC19M003738

Summaries for EEF2 Gene

Entrez Gene Summary for EEF2 Gene

  • This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by EF-2 kinase phosporylation. [provided by RefSeq, Jul 2008]

GeneCards Summary for EEF2 Gene

EEF2 (Eukaryotic Translation Elongation Factor 2) is a Protein Coding gene. Diseases associated with EEF2 include Spinocerebellar Ataxia 26 and Diphtheria. Among its related pathways are Gamma carboxylation, hypusine formation and arylsulfatase activation and Beta-Adrenergic Signaling. Gene Ontology (GO) annotations related to this gene include protein kinase binding. An important paralog of this gene is EFTUD2.

UniProtKB/Swiss-Prot Summary for EEF2 Gene

  • Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

Gene Wiki entry for EEF2 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for EEF2 Gene

Genomics for EEF2 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for EEF2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around EEF2 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for EEF2

Top Transcription factor binding sites by QIAGEN in the EEF2 gene promoter:
  • c-Myb
  • C/EBPalpha
  • p53
  • Sp1
  • STAT5A
  • TBP
  • YY1

Genomic Locations for EEF2 Gene

Latest Assembly
chr19:3,976,056-3,985,463
(GRCh38/hg38)
Size:
9,408 bases
Orientation:
Minus strand

Previous Assembly
chr19:3,976,054-3,985,461
(GRCh37/hg19 by Entrez Gene)
Size:
9,408 bases
Orientation:
Minus strand

chr19:3,976,054-3,985,467
(GRCh37/hg19 by Ensembl)
Size:
9,414 bases
Orientation:
Minus strand

Genomic View for EEF2 Gene

Genes around EEF2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
EEF2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for EEF2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for EEF2 Gene

Proteins for EEF2 Gene

  • Protein details for EEF2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P13639-EF2_HUMAN
    Recommended name:
    Elongation factor 2
    Protein Accession:
    P13639
    Secondary Accessions:
    • B2RMP5
    • D6W618
    • Q58J86

    Protein attributes for EEF2 Gene

    Size:
    858 amino acids
    Molecular mass:
    95338 Da
    Quaternary structure:
    • Component of the mRNA surveillance SURF complex, at least composed of ERF1, ERF3 (ERF3A or ERF3B), EEF2, UPF1/RENT1, SMG1, SMG8 and SMG9 (PubMed:19417104). Interacts with RBPMS2 (PubMed:25064856).

    Three dimensional structures from OCA and Proteopedia for EEF2 Gene

neXtProt entry for EEF2 Gene

Post-translational modifications for EEF2 Gene

  • Phosphorylation by EF-2 kinase completely inactivates EF-2; it requires prior phosphorylation by CDK2 at Ser-595 during mitotic prometaphase. Phosphorylation by CSK promotes SUMOylation, proteolytic cleavage, and nuclear translocation if the C-terminal fragment.
  • Diphthamide is 2-[3-carboxyamido-3-(trimethyl-ammonio)propyl]histidine (By similarity).
  • (Microbial infection) Diphthamide can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A, thus arresting protein synthesis.
  • ISGylated.
  • Proteolytically processed at two sites following phosphorylation by CSK.
  • SUMOylated following phosphorylation by CSK, promotes proteolytic cleavage.
  • Ubiquitination at Lys32, Lys42, Lys152, Lys159, Lys235, Lys239, Lys272, Lys275, Lys318, Lys333, Lys366, Lys386, Lys426, Lys481, Lys498, Lys512, Lys594, Lys638, Lys648, Lys688, and Lys845
  • Modification sites at PhosphoSitePlus

Other Protein References for EEF2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for EEF2 Gene

Domains & Families for EEF2 Gene

Gene Families for EEF2 Gene

HGNC:
Human Protein Atlas (HPA):
  • Cancer-related genes
  • Disease related genes
  • Plasma proteins
  • Predicted intracellular proteins

Protein Domains for EEF2 Gene

Suggested Antigen Peptide Sequences for EEF2 Gene

GenScript: Design optimal peptide antigens:
  • cDNA FLJ60696, highly similar to Elongation factor 2 (B4DMC6_HUMAN)
  • cDNA FLJ56548, highly similar to Elongation factor 2 (B4DPU3_HUMAN)
  • Elongation factor 2 (EF2_HUMAN)
  • EEF2 protein (Q6PK56_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P13639

UniProtKB/Swiss-Prot:

EF2_HUMAN :
  • Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
Family:
  • Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
genes like me logo Genes that share domains with EEF2: view

Function for EEF2 Gene

Molecular function for EEF2 Gene

UniProtKB/Swiss-Prot Function:
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
GENATLAS Biochemistry:
eukaryotic translation elongation factor 2

Phenotypes From GWAS Catalog for EEF2 Gene

Gene Ontology (GO) - Molecular Function for EEF2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
GO:0002039 p53 binding IEA --
GO:0003723 RNA binding IEA,HDA 22658674
GO:0003746 translation elongation factor activity IBA 21873635
GO:0003924 GTPase activity IBA 21873635
genes like me logo Genes that share ontologies with EEF2: view
genes like me logo Genes that share phenotypes with EEF2: view

Human Phenotype Ontology for EEF2 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

miRNA for EEF2 Gene

miRTarBase miRNAs that target EEF2

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for EEF2

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for EEF2 Gene

Localization for EEF2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for EEF2 Gene

Cytoplasm. Nucleus. Note=Phosphorylation by CSK promotes cleavage and SUMOylation-dependent nuclear translocation of the C-terminal cleavage product. {ECO:0000269 PubMed:24648518}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for EEF2 gene
Compartment Confidence
plasma membrane 5
nucleus 5
cytosol 5
extracellular 4
cytoskeleton 3
golgi apparatus 3
mitochondrion 2
endoplasmic reticulum 2
endosome 2
lysosome 2
peroxisome 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (4)
  • Plasma membrane (4)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for EEF2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region TAS --
GO:0005634 nucleus IEA,HDA 21630459
GO:0005737 cytoplasm IEA,IDA 25064856
GO:0005829 cytosol TAS --
GO:0005844 polysome IEA --
genes like me logo Genes that share ontologies with EEF2: view

Pathways & Interactions for EEF2 Gene

genes like me logo Genes that share pathways with EEF2: view

Pathways by source for EEF2 Gene

3 GeneGo (Thomson Reuters) pathways for EEF2 Gene
  • Regulation of lipid metabolism Insulin signaling-generic cascades
  • Translation Insulin regulation of translation
  • Translation Translation regulation by Alpha-1 adrenergic receptors
1 R&D Systems pathway for EEF2 Gene
2 Qiagen pathways for EEF2 Gene
  • Insulin Receptor Pathway
  • p70S6K Signaling
1 Cell Signaling Technology pathway for EEF2 Gene

SIGNOR curated interactions for EEF2 Gene

Is activated by:
Is inactivated by:

Gene Ontology (GO) - Biological Process for EEF2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002244 hematopoietic progenitor cell differentiation IEA --
GO:0002931 response to ischemia IEA --
GO:0003009 skeletal muscle contraction IEA --
GO:0006412 translation IEA --
GO:0006414 translational elongation TAS --
genes like me logo Genes that share ontologies with EEF2: view

Drugs & Compounds for EEF2 Gene

(36) Drugs for EEF2 Gene - From: DrugBank, DGIdb, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Esketamine Approved, Investigational Pharma Target, inhibitor 88
Moxetumomab pasudotox Approved, Investigational Pharma Target, inactivator 0
Water Approved Pharma 0
Guanosine diphosphate Experimental Pharma Target 0
Diphthamide Experimental Pharma Target 0

(21) Additional Compounds for EEF2 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with EEF2: view

Transcripts for EEF2 Gene

mRNA/cDNA for EEF2 Gene

1 REFSEQ mRNAs :
13 NCBI additional mRNA sequence :
7 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for EEF2

Alternative Splicing Database (ASD) splice patterns (SP) for EEF2 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6a · 6b · 6c · 6d ^ 7 ^ 8 ^ 9a · 9b ^ 10a · 10b ^ 11 ^ 12 ^ 13a · 13b · 13c · 13d ^ 14 ^ 15 ^
SP1: -
SP2: - -
SP3: - - - - - - - - - - - - - -
SP4: - - - - - - - - - - - - - - - - - - - -
SP5:
SP6: - - - - - - - - - - -
SP7: - - -
SP8:
SP9:

ExUns: 16a · 16b ^ 17a · 17b · 17c ^ 18
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7: - - - - -
SP8: - -
SP9:

Relevant External Links for EEF2 Gene

GeneLoc Exon Structure for
EEF2

Expression for EEF2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for EEF2 Gene

Protein differential expression in normal tissues from HIPED for EEF2 Gene

This gene is overexpressed in Lymph node (10.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for EEF2 Gene



Protein tissue co-expression partners for EEF2 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for EEF2

SOURCE GeneReport for Unigene cluster for EEF2 Gene:

Hs.515070

Evidence on tissue expression from TISSUES for EEF2 Gene

  • Nervous system(5)
  • Liver(4.8)
  • Intestine(4.8)
  • Blood(4.7)
  • Lung(4.5)
  • Muscle(4.3)
  • Heart(4.2)
  • Stomach(4.1)
  • Kidney(4)
  • Skin(4)
  • Thyroid gland(3.7)
  • Eye(3.5)
  • Pancreas(3.4)
  • Spleen(3.2)
  • Lymph node(3.2)
  • Bone marrow(3.2)
  • Adrenal gland(3)
  • Gall bladder(2.5)

Phenotype-based relationships between genes and organs from Gene ORGANizer for EEF2 Gene

Germ Layers:
  • ectoderm
  • mesoderm
Systems:
  • nervous
  • skeletal muscle
  • skeleton
Regions:
Head and neck:
  • brain
  • cerebellum
  • cranial nerve
  • eye
  • head
Limb:
  • lower limb
  • upper limb
General:
  • peripheral nerve
  • peripheral nervous system
  • spinal cord
genes like me logo Genes that share expression patterns with EEF2: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for EEF2 Gene

Orthologs for EEF2 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for EEF2 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia EEF2 30
  • 99 (a)
OneToOne
LOC100614367 29
  • 98.89 (n)
Oppossum
(Monodelphis domestica)
Mammalia -- 30
  • 99 (a)
OneToMany
-- 30
  • 98 (a)
OneToMany
Platypus
(Ornithorhynchus anatinus)
Mammalia EEF2 30
  • 99 (a)
OneToOne
Cow
(Bos Taurus)
Mammalia EEF2 29 30
  • 90.75 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia EEF2 29 30
  • 89.51 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Eef2 29
  • 88.46 (n)
Mouse
(Mus musculus)
Mammalia Eef2 29 16 30
  • 88.42 (n)
OneToOne
Chicken
(Gallus gallus)
Aves EEF2 29 30
  • 85.63 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia EEF2 30
  • 95 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia eef2.1 29
  • 79.02 (n)
MGC76191 29
African clawed frog
(Xenopus laevis)
Amphibia eef2-prov 29
Zebrafish
(Danio rerio)
Actinopterygii eef2l2 30
  • 92 (a)
OneToOne
eef2b 29
  • 82.44 (n)
zgc63584 29
Rainbow Trout
(Oncorhynchus mykiss)
Actinopterygii Omy.9660 29
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP009441 29
  • 75.71 (n)
Fruit Fly
(Drosophila melanogaster)
Insecta Ef2b 29 30 31
  • 73.1 (n)
ManyToMany
Worm
(Caenorhabditis elegans)
Secernentea eft-2 31
  • 78 (a)
eef-2 29 30
  • 71.59 (n)
ManyToMany
K10C3.5 31
  • 28 (a)
Baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes EFT2 30 32
  • 67 (a)
OneToMany
EFT1 32
Thale Cress
(Arabidopsis thaliana)
eudicotyledons LOS1 29
  • 62.93 (n)
Alicante grape
(Vitis vinifera)
eudicotyledons Vvi.6678 29
Soybean
(Glycine max)
eudicotyledons Gma.10782 29
Rice
(Oryza sativa)
Liliopsida Os01g0742200 29
  • 63.16 (n)
Wheat
(Triticum aestivum)
Liliopsida Ta.5736 29
Sea Squirt
(Ciona savignyi)
Ascidiacea CSA.11302 30
  • 75 (a)
ManyToMany
Species where no ortholog for EEF2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)

Evolution for EEF2 Gene

ENSEMBL:
Gene Tree for EEF2 (if available)
TreeFam:
Gene Tree for EEF2 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for EEF2: view image
Alliance of Genome Resources:
Additional Orthologs for EEF2

Paralogs for EEF2 Gene

(3) SIMAP similar genes for EEF2 Gene using alignment to 3 proteins:

  • EF2_HUMAN
  • M0R0I6_HUMAN
  • Q6PK56_HUMAN
genes like me logo Genes that share paralogs with EEF2: view

Variants for EEF2 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for EEF2 Gene

SNP ID Clinical significance and condition Chr 19 pos Variation AA Info Type
994601 Benign: not specified 3,976,551(-) C/T
NM_001961.4(EEF2):c.*3G>A
THREE_PRIME_UTR
994602 Uncertain Significance: not provided 3,980,841(-) C/A
NM_001961.4(EEF2):c.1150G>T (p.Gly384Cys)
MISSENSE
994603 Likely Benign: not provided 3,980,567(-) C/T
NM_001961.4(EEF2):c.1293G>A (p.Gly431=)
SYNONYMOUS
994604 Likely Benign: not provided 3,979,934(-) G/A
NM_001961.4(EEF2):c.1479C>T (p.Asn493=)
SYNONYMOUS
994605 Likely Benign: not provided 3,977,990(-) C/T
NM_001961.4(EEF2):c.1896G>A (p.Ala632=)
SYNONYMOUS

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for EEF2 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for EEF2 Gene

Variant ID Type Subtype PubMed ID
esv1001715 CNV deletion 20482838
nsv2392 CNV insertion 18451855
nsv833715 CNV loss 17160897
nsv953949 CNV deletion 24416366

Variation tolerance for EEF2 Gene

Residual Variation Intolerance Score: 0.879% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.37; 8.26% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for EEF2 Gene

Human Gene Mutation Database (HGMD)
EEF2
SNPedia medical, phenotypic, and genealogical associations of SNPs for
EEF2
Leiden Open Variation Database (LOVD)
EEF2

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for EEF2 Gene

Disorders for EEF2 Gene

MalaCards: The human disease database

(14) MalaCards diseases for EEF2 Gene - From: OMI, CVR, GTR, ORP, SWI, COP, and GCD

Disorder Aliases PubMed IDs
spinocerebellar ataxia 26
  • sca26
diphtheria
  • corynebacterium infection
myotonic dystrophy 2
  • dm2
refractory hematologic cancer
  • refractory hematologic malignancy
refractory hairy cell leukemia
- elite association - COSMIC cancer census association via MalaCards
Search EEF2 in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

EF2_HUMAN
  • Spinocerebellar ataxia 26 (SCA26) [MIM:609306]: A form of spinocerebellar ataxia, a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. {ECO:0000269 PubMed:23001565}. Note=The disease is caused by variants affecting the gene represented in this entry.

Additional Disease Information for EEF2

Human Genome Epidemiology Navigator
(HuGE)
Atlas
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
Open Targets Platform
genes like me logo Genes that share disorders with EEF2: view

No data available for Genatlas for EEF2 Gene

Publications for EEF2 Gene

  1. A conserved eEF2 coding variant in SCA26 leads to loss of translational fidelity and increased susceptibility to proteostatic insult. (PMID: 23001565) Hekman KE … Gomez CM (Human molecular genetics 2012) 3 4 72
  2. Complete sequence of the coding region of human elongation factor 2 (EF-2) by enzymatic amplification of cDNA from human ovarian granulosa cells. (PMID: 2610926) Rapp G … Scheit KH (Biological chemistry Hoppe-Seyler 1989) 2 3 4
  3. C-terminal Src kinase (Csk)-mediated phosphorylation of eukaryotic elongation factor 2 (eEF2) promotes proteolytic cleavage and nuclear translocation of eEF2. (PMID: 24648518) Yao Q … Guo L (The Journal of biological chemistry 2014) 3 4
  4. Homodimerization of RBPMS2 through a new RRM-interaction motif is necessary to control smooth muscle plasticity. (PMID: 25064856) Sagnol S … de Santa Barbara P (Nucleic acids research 2014) 3 4
  5. Identification and characterization of a novel evolutionarily conserved lysine-specific methyltransferase targeting eukaryotic translation elongation factor 2 (eEF2). (PMID: 25231979) Davydova E … Falnes PØ (The Journal of biological chemistry 2014) 3 4

Products for EEF2 Gene

Sources for EEF2 Gene