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Aliases for EEF1E1-BLOC1S5 Gene

Subcategory (RNA class) for EEF1E1-BLOC1S5 Gene


Quality Score for this RNA gene is


Aliases for EEF1E1-BLOC1S5 Gene

  • EEF1E1-BLOC1S5 Readthrough (NMD Candidate) 2 3 5
  • EEF1E1-MUTED Readthrough 3
  • EEF1E1-MUTED 3
  • HCG2043275 12

External Ids for EEF1E1-BLOC1S5 Gene

Previous GeneCards Identifiers for EEF1E1-BLOC1S5 Gene

  • GC06M008018

Summaries for EEF1E1-BLOC1S5 Gene

Entrez Gene Summary for EEF1E1-BLOC1S5 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1) and MUTED (muted homolog) genes on chromosome 6. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD) and is unlikely to produce a protein product. [provided by RefSeq, Dec 2010]

GeneCards Summary for EEF1E1-BLOC1S5 Gene

EEF1E1-BLOC1S5 (EEF1E1-BLOC1S5 Readthrough (NMD Candidate)) is an RNA Gene, and is affiliated with the ncRNA class. An important paralog of this gene is EEF1E1.

Additional gene information for EEF1E1-BLOC1S5 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for EEF1E1-BLOC1S5 Gene

Genomics for EEF1E1-BLOC1S5 Gene

GeneHancer (GH) Regulatory Elements for EEF1E1-BLOC1S5 Gene

Promoters and enhancers for EEF1E1-BLOC1S5 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06J008099 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE 650.7 +1.1 1062 3.6 HDGF PKNOX1 CLOCK FOXA2 MLX ARNT ZFP64 ARID4B SIN3A FEZF1 EEF1E1 ENSG00000232234 EEF1E1-BLOC1S5 RREB1 ENSG00000225092 GC06P008087 GC06M008098
GH06J008079 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 0.4 +19.1 19127 7.3 FOXA2 MLX ARID4B FEZF1 ZNF2 YY1 FOS KLF13 SP3 SP5 RIOK1 SNRNP48 EEF1E1 BLOC1S5 SCARNA27 BLOC1S5-TXNDC5 EEF1E1-BLOC1S5
GH06J008063 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 0.3 +37.9 37914 2.8 MLX ZFP64 FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF143 BLOC1S5 BLOC1S5-TXNDC5 LOC100422646 SCARNA27 EEF1E1-BLOC1S5
GH06J008047 Enhancer 0.7 Ensembl ENCODE 0.2 +54.6 54591 0.9 FOSL1 JUND GATA3 JUN FOS CUX1 PRDM1 BLOC1S5 BLOC1S5-TXNDC5 GC06M007999 EEF1E1-BLOC1S5
GH06J008015 Promoter 0.6 EPDnew 0.2 +86.8 86814 0.1 MITF PIR57650 BLOC1S5 GC06M007999 BLOC1S5-TXNDC5 EEF1E1-BLOC1S5
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around EEF1E1-BLOC1S5 on UCSC Golden Path with GeneCards custom track

Genomic Locations for EEF1E1-BLOC1S5 Gene

Genomic Locations for EEF1E1-BLOC1S5 Gene
89,029 bases
Minus strand
89,029 bases
Minus strand

Genomic View for EEF1E1-BLOC1S5 Gene

Genes around EEF1E1-BLOC1S5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
EEF1E1-BLOC1S5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for EEF1E1-BLOC1S5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for EEF1E1-BLOC1S5 Gene

Proteins for EEF1E1-BLOC1S5 Gene

  • Protein details for EEF1E1-BLOC1S5 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    EEF1E1-BLOC1S5 readthrough (NMD candidate)
    Protein Accession:

    Protein attributes for EEF1E1-BLOC1S5 Gene

    151 amino acids
    Molecular mass:
    17018 Da
    Quaternary structure:
    No Data Available

neXtProt entry for EEF1E1-BLOC1S5 Gene

Protein Expression for EEF1E1-BLOC1S5 Gene

Post-translational modifications for EEF1E1-BLOC1S5 Gene

No Post-translational modifications

Other Protein References for EEF1E1-BLOC1S5 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for EEF1E1-BLOC1S5 Gene

Domains & Families for EEF1E1-BLOC1S5 Gene

Protein Domains for EEF1E1-BLOC1S5 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with EEF1E1-BLOC1S5: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for EEF1E1-BLOC1S5 Gene

Function for EEF1E1-BLOC1S5 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for EEF1E1-BLOC1S5 Gene

Localization for EEF1E1-BLOC1S5 Gene

Gene Ontology (GO) - Cellular Components for EEF1E1-BLOC1S5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IBA --
genes like me logo Genes that share ontologies with EEF1E1-BLOC1S5: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for EEF1E1-BLOC1S5 Gene

Pathways & Interactions for EEF1E1-BLOC1S5 Gene

SuperPathways for EEF1E1-BLOC1S5 Gene

No Data Available

Interacting Proteins for EEF1E1-BLOC1S5 Gene

Gene Ontology (GO) - Biological Process for EEF1E1-BLOC1S5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006749 glutathione metabolic process IBA --
genes like me logo Genes that share ontologies with EEF1E1-BLOC1S5: view

No data available for Pathways by source and SIGNOR curated interactions for EEF1E1-BLOC1S5 Gene

Drugs & Compounds for EEF1E1-BLOC1S5 Gene

No Compound Related Data Available

Transcripts for EEF1E1-BLOC1S5 Gene

mRNA/cDNA for EEF1E1-BLOC1S5 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(1) RNA Central transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for EEF1E1-BLOC1S5 Gene

No ASD Table

Relevant External Links for EEF1E1-BLOC1S5 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for EEF1E1-BLOC1S5 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from MOPED for EEF1E1-BLOC1S5 Gene

Protein tissue co-expression partners for EEF1E1-BLOC1S5 Gene

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for EEF1E1-BLOC1S5 Gene

Orthologs for EEF1E1-BLOC1S5 Gene

This gene was present in the common ancestor of animals.

Orthologs for EEF1E1-BLOC1S5 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia EEF1E1 34
  • 76 (a)
(Bos Taurus)
Mammalia EEF1E1 34
  • 74 (a)
(Canis familiaris)
Mammalia -- 34
  • 74 (a)
(Mus musculus)
Mammalia Eef1e1 34
  • 66 (a)
(Monodelphis domestica)
Mammalia -- 34
  • 66 (a)
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 52 (a)
(Gallus gallus)
Aves -- 34
  • 55 (a)
(Anolis carolinensis)
Reptilia -- 34
  • 59 (a)
(Danio rerio)
Actinopterygii eef1e1 34
  • 47 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG30185 34
  • 22 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.2900 34
  • 25 (a)
Species where no ortholog for EEF1E1-BLOC1S5 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for EEF1E1-BLOC1S5 Gene

Gene Tree for EEF1E1-BLOC1S5 (if available)
Gene Tree for EEF1E1-BLOC1S5 (if available)

Paralogs for EEF1E1-BLOC1S5 Gene

Paralogs for EEF1E1-BLOC1S5 Gene

(1) SIMAP similar genes for EEF1E1-BLOC1S5 Gene using alignment to 1 proteins:

  • C9J1V9_HUMAN
genes like me logo Genes that share paralogs with EEF1E1-BLOC1S5: view

Variants for EEF1E1-BLOC1S5 Gene

Sequence variations from dbSNP and Humsavar for EEF1E1-BLOC1S5 Gene

SNP ID Clin Chr 06 pos Variation AA Info Type
rs1000004139 -- 8,060,950(-) G/A intron_variant
rs1000041649 -- 8,087,392(-) A/G intron_variant
rs1000052198 -- 8,073,076(-) A/G intron_variant
rs1000123610 -- 8,045,929(-) A/T intron_variant
rs1000149057 -- 8,063,996(-) G/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for EEF1E1-BLOC1S5 Gene

Variant ID Type Subtype PubMed ID
esv2662813 CNV deletion 23128226
esv2672674 CNV deletion 23128226
esv2731544 CNV deletion 23290073
esv3306258 CNV mobile element insertion 20981092
esv3356211 CNV insertion 20981092
esv3570754 CNV loss 25503493
esv3576096 CNV gain 25503493
esv3608024 CNV loss 21293372
esv3608025 CNV loss 21293372
nsv1074375 CNV deletion 25765185
nsv1109758 CNV deletion 24896259
nsv1124025 CNV deletion 24896259
nsv1133014 OTHER inversion 24896259
nsv1151332 OTHER inversion 26484159
nsv478355 CNV novel sequence insertion 20440878
nsv600924 CNV gain 21841781
nsv600927 CNV gain 21841781

Additional Variant Information for EEF1E1-BLOC1S5 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for EEF1E1-BLOC1S5 Gene

Disorders for EEF1E1-BLOC1S5 Gene

Additional Disease Information for EEF1E1-BLOC1S5

No disorders were found for EEF1E1-BLOC1S5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for EEF1E1-BLOC1S5 Gene

Publications for EEF1E1-BLOC1S5 Gene

  1. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T … Taylor TD (PloS one 2010) 3 58

Products for EEF1E1-BLOC1S5 Gene

Sources for EEF1E1-BLOC1S5 Gene

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