Aliases for ECHDC1 Gene
External Ids for ECHDC1 Gene
Previous GeneCards Identifiers for ECHDC1 Gene
GeneCards Summary for ECHDC1 Gene
ECHDC1 (Ethylmalonyl-CoA Decarboxylase 1) is a Protein Coding gene. Diseases associated with ECHDC1 include Schizophrenia 13 and Extratemporal Epilepsy. Among its related pathways are Metabolism and Fatty Acid Biosynthesis (WikiPathways). Gene Ontology (GO) annotations related to this gene include carboxy-lyase activity and methylmalonyl-CoA decarboxylase activity. An important paralog of this gene is AUH.
UniProtKB/Swiss-Prot Summary for ECHDC1 Gene
Decarboxylates ethylmalonyl-CoA, a potentially toxic metabolite, to form butyryl-CoA, suggesting it might be involved in metabolite proofreading (PubMed:22016388). Also has methylmalonyl-CoA decarboxylase activity at lower level (By similarity).