Aliases for ECE2 Gene
External Ids for ECE2 Gene
Previous GeneCards Identifiers for ECE2 Gene
GeneCards Summary for ECE2 Gene
ECE2 (Endothelin Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ECE2 include Alzheimer Disease. Among its related pathways are Peptide ligand-binding receptors and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include methyltransferase activity and metalloendopeptidase activity. An important paralog of this gene is ECE1.
UniProtKB/Swiss-Prot for ECE2 Gene
Converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May limit amyloid-beta peptide accumulation in brain. May also have methyltransferase activity.