Aliases for EBAG9 Gene
External Ids for EBAG9 Gene
Previous GeneCards Identifiers for EBAG9 Gene
This gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor, which binds to the estrogen-responsive element found in the 5'-flanking region of this gene. The encoded protein is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. Alternate splicing results in multiple transcript variants. A pseudogene of this gene has been defined on chromosome 10. [provided by RefSeq, Jul 2013]
GeneCards Summary for EBAG9 Gene
EBAG9 (Estrogen Receptor Binding Site Associated Antigen 9) is a Protein Coding gene. Diseases associated with EBAG9 include Cervical Adenocarcinoma and Placental Abruption. Among its related pathways are Relaxin signaling pathway and Translational Control. Gene Ontology (GO) annotations related to this gene include peptidase activator activity involved in apoptotic process.
UniProtKB/Swiss-Prot Summary for EBAG9 Gene
May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.