Aliases for DYNLL2 Gene
External Ids for DYNLL2 Gene
Previous GeneCards Identifiers for DYNLL2 Gene
GeneCards Summary for DYNLL2 Gene
DYNLL2 (Dynein Light Chain LC8-Type 2) is a Protein Coding gene. Diseases associated with DYNLL2 include Short-Rib Thoracic Dysplasia 11 With Or Without Polydactyly and Bardet-Biedl Syndrome 7. Among its related pathways are Cell cycle_Spindle assembly and chromosome separation and Organelle biogenesis and maintenance. Gene Ontology (GO) annotations related to this gene include motor activity and cytoskeletal protein binding. An important paralog of this gene is DYNLL1.
UniProtKB/Swiss-Prot Summary for DYNLL2 Gene
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity).