Aliases for DYNLL2 Gene
External Ids for DYNLL2 Gene
Previous GeneCards Identifiers for DYNLL2 Gene
GeneCards Summary for DYNLL2 Gene
DYNLL2 (Dynein Light Chain LC8-Type 2) is a Protein Coding gene. Diseases associated with DYNLL2 include Short-Rib Thoracic Dysplasia 11 With Or Without Polydactyly and Bardet-Biedl Syndrome 7. Among its related pathways are Macroautophagy and Vesicle-mediated transport. Gene Ontology (GO) annotations related to this gene include motor activity and cytoskeletal protein binding. An important paralog of this gene is DYNLL1.
UniProtKB/Swiss-Prot Summary for DYNLL2 Gene
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity).