Aliases for DVL3 Gene
External Ids for DVL3 Gene
Previous GeneCards Identifiers for DVL3 Gene
This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation. [provided by RefSeq, Jul 2008]
GeneCards Summary for DVL3 Gene
DVL3 (Dishevelled Segment Polarity Protein 3) is a Protein Coding gene. Diseases associated with DVL3 include Robinow Syndrome, Autosomal Dominant 3 and Robinow Syndrome, Autosomal Dominant 1. Among its related pathways are Regulation of activated PAK-2p34 by proteasome mediated degradation and Regulation of Wnt-mediated beta catenin signaling and target gene transcription. Gene Ontology (GO) annotations related to this gene include protein heterodimerization activity and protease binding. An important paralog of this gene is DVL2.
UniProtKB/Swiss-Prot Summary for DVL3 Gene
Involved in the signal transduction pathway mediated by multiple Wnt genes.