Aliases for DUSP16 Gene
External Ids for DUSP16 Gene
Previous GeneCards Identifiers for DUSP16 Gene
This gene encodes a mitogen-activated protein kinase phosphatase that is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. The encoded protein specifically regulates the c-Jun amino-terminal kinase (JNK) and extracellular signal-regulated kinase (ERK) pathways.[provided by RefSeq, May 2010]
GeneCards Summary for DUSP16 Gene
DUSP16 (Dual Specificity Phosphatase 16) is a Protein Coding gene. Diseases associated with DUSP16 include Obstructive Hydrocephalus. Among its related pathways are Signaling by GPCR and MAPK signaling pathway. Gene Ontology (GO) annotations related to this gene include phosphatase activity and phosphoprotein phosphatase activity. An important paralog of this gene is DUSP8.
UniProtKB/Swiss-Prot Summary for DUSP16 Gene
Dual specificity protein phosphatase involved in the inactivation of MAP kinases. Dephosphorylates MAPK10 bound to ARRB2.