Aliases for DUSP15 Gene
External Ids for DUSP15 Gene
Previous HGNC Symbols for DUSP15 Gene
Previous GeneCards Identifiers for DUSP15 Gene
The protein encoded by this gene has both protein-tyrosine phophatase activity and serine/threonine-specific phosphatase activity, and therefore is known as a dual specificity phosphatase. This protein may function in the differentiation of oligodendrocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
GeneCards Summary for DUSP15 Gene
DUSP15 (Dual Specificity Phosphatase 15) is a Protein Coding gene. Diseases associated with DUSP15 include Nanophthalmos. Gene Ontology (GO) annotations related to this gene include phosphatase activity and protein tyrosine/serine/threonine phosphatase activity. An important paralog of this gene is DUSP22.
UniProtKB/Swiss-Prot Summary for DUSP15 Gene
May dephosphorylate MAPK13, ATF2, ERBB3, PDGFRB and SNX6 (PubMed:22792334).
[Isoform 3]: May play a role in the regulation of oligodendrocyte differentiation. May play a role in the regulation of myelin formation (By similarity). Involved in the regulation of Erk1/2 phosphorylation in Schwann cells; the signaling may be linked to the regulation of myelination (By similarity).