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Aliases for DTX4 Gene
Aliases for DTX4 Gene
External Ids for DTX4 Gene
- HGNC: 29151
- NCBI Entrez Gene: 23220
- Ensembl: ENSG00000110042
- OMIM®: 616110
- UniProtKB/Swiss-Prot: Q9Y2E6
Previous GeneCards Identifiers for DTX4 Gene
- GC11P058715
- GC11P058695
- GC11P058939
- GC11P055285
Summaries for DTX4 Gene
GeneCards Summary for DTX4 Gene
DTX4 (Deltex E3 Ubiquitin Ligase 4) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Cytosolic sensors of pathogen-associated DNA. Gene Ontology (GO) annotations related to this gene include ligase activity. An important paralog of this gene is DTX1.
UniProtKB/Swiss-Prot Summary for DTX4 Gene
-
Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations (By similarity). Functions as a ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.
Additional gene information for DTX4 Gene
- HGNC (29151)
- NCBI Entrez Gene (23220)
- Ensembl (ENSG00000110042)
- OMIM® (616110)
- UniProtKB/Swiss-Prot (Q9Y2E6)
- Open Targets Platform(ENSG00000110042)
- Monarch Initiative
- Search for DTX4 at DataMed
- Search for DTX4 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for DTX4 Gene
Genomics for DTX4 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for DTX4 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around DTX4 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for DTX4
- Top Transcription factor binding sites by QIAGEN in the DTX4 gene promoter:
-
- AREB6
- c-Myb
- E4BP4
- Hlf
- LCR-F1
- MyoD
- Nkx2-5
- NRSF form 1
- NRSF form 2
- Pax-5
Genomic Locations for DTX4 Gene
Latest Assembly
- chr11:59,171,430-59,208,588
- (GRCh38/hg38)
- Size:
- 37,159 bases
- Orientation:
- Plus strand
Previous Assembly
- chr11:58,938,903-58,976,061
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 37,159 bases
- Orientation:
- Plus strand
- chr11:58,938,903-58,976,060
- (GRCh37/hg19 by Ensembl)
- Size:
- 37,158 bases
- Orientation:
- Plus strand
Genomic View for DTX4 Gene
Genes around DTX4 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11q12.1 by HGNC
- 11q12.1 by Entrez Gene
- 11q12.1 by Ensembl
DTX4 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for DTX4 Gene
Proteins for DTX4 Gene
-
Protein details for DTX4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9Y2E6-DTX4_HUMAN
- Recommended name:
- E3 ubiquitin-protein ligase DTX4
- Protein Accession:
- Q9Y2E6
- Q0VF38
Protein attributes for DTX4 Gene
- Size:
- 619 amino acids
- Molecular mass:
- 67258 Da
- Quaternary structure:
-
- Interacts with NLRP4.
- SequenceCaution:
-
- Sequence=BAA76781.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
Protein Expression for DTX4 Gene
Post-translational modifications for DTX4 Gene
Other Protein References for DTX4 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- LifeSpan BioSciences DTX4 Antibody
- Novus Biologicals Antibodies for DTX4
- Invitrogen Antibodies for DTX4 (AFLGC-DTX4)
-
Boster Bio Antibodies for DTX4
-
Custom Antibody ServicesProSci Antibodies for DTX4
Protein products for research
-
OriGene Purified Proteins for DTX4
- Search Origene for MassSpec and Protein Over-expression Lysates for DTX4
- Origene Custom Protein Services for DTX4
- Novus Biologicals proteins for DTX4
Assay products for research
No data available for DME Specific Peptides for DTX4 Gene
Domains & Families for DTX4 Gene
Gene Families for DTX4 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Enzymes
- Predicted intracellular proteins
Protein Domains for DTX4 Gene
- InterPro:
- Blocks:
-
- Zn-finger, RING
- ProtoNet:
Suggested Antigen Peptide Sequences for DTX4 Gene
- GenScript: Design optimal peptide antigens:
-
- RING finger protein 155 (DTX4_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9Y2E6UniProtKB/Swiss-Prot:
DTX4_HUMAN :- The WWE domains are thought to mediate some protein-protein interaction, and are frequently found in ubiquitin ligases.
- Belongs to the Deltex family.
- Domain:
-
- The WWE domains are thought to mediate some protein-protein interaction, and are frequently found in ubiquitin ligases.
- Family:
-
- Belongs to the Deltex family.
Function for DTX4 Gene
Molecular function for DTX4 Gene
- UniProtKB/Swiss-Prot Function:
- Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations (By similarity). Functions as a ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.
- UniProtKB/Swiss-Prot CatalyticActivity:
- Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.; EC=2.3.2.27; Evidence={ECO:0000250|UniProtKB:Q61010};.
Enzyme Numbers (IUBMB) for DTX4 Gene
Phenotypes From GWAS Catalog for DTX4 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004842 | ubiquitin-protein transferase activity | TAS | -- |
| GO:0008270 | zinc ion binding | IEA | -- |
| GO:0016740 | transferase activity | IEA | -- |
| GO:0046872 | metal ion binding | IEA | -- |
| GO:0061630 | ubiquitin protein ligase activity | IBA | 21873635 |
Phenotypes for DTX4 Gene
- MGI mutant phenotypes for DTX4:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for DTX4:
-
- Increased gamma-H2AX phosphorylation
- Decreased hepcidin::fluc mRNA expression
- Synthetic lethal with Ras
- Decreased ionizing radiation sensitivity
- Decreased HIV-LTR-beta-galactosidase protein expression
- Increased cell death HMECs cells
- Increased number of cells in monopolar arrest with EMD534085 (a Kinesin-5 inhibitor)
- Decreased Tat-dependent HIV-LTR-beta-galactosidase protein expression
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for DTX4 - Starting at $85 >
- * DTX4 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for DTX4
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for DTX4
-
Santa Cruz Biotechnology (SCBT) CRISPR for DTX4
miRNA for DTX4 Gene
- miRTarBase miRNAs that target DTX4
-
- hsa-miR-98-5p (MIRT027766)
- hsa-miR-1277-5p (MIRT512006)
- hsa-miR-190a-3p (MIRT512007)
- hsa-miR-586 (MIRT512008)
- hsa-miR-5011-5p (MIRT512009)
- hsa-miR-598-3p (MIRT512010)
- hsa-miR-448 (MIRT512011)
- hsa-miR-6715b-3p (MIRT523995)
- hsa-miR-6715a-3p (MIRT523996)
- hsa-miR-6771-3p (MIRT558310)
- hsa-miR-152-3p (MIRT715173)
- hsa-miR-148b-3p (MIRT715174)
- hsa-miR-148a-3p (MIRT715175)
- hsa-miR-5003-5p (MIRT715176)
- hsa-miR-4709-5p (MIRT715177)
- hsa-miR-454-3p (MIRT715178)
- hsa-miR-4295 (MIRT715179)
- hsa-miR-3666 (MIRT715180)
- hsa-miR-301b-3p (MIRT715181)
- hsa-miR-301a-3p (MIRT715182)
- hsa-miR-130b-3p (MIRT715183)
- hsa-miR-130a-3p (MIRT715184)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for DTX4
- Browse OriGene Inhibitory RNA Products For DTX4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for DTX4
Clone products for research
- Applied Biological Materials (abm): Clones for DTX4 - Starting at $45 >
- * DTX4 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for DTX4
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for DTX4
Cell Lines for research
-
Horizon Cell Lines for DTX4
No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for DTX4 Gene
Localization for DTX4 Gene
Subcellular locations from UniProtKB/Swiss-Prot for DTX4 Gene
- Cytoplasm.
| Compartment | Confidence |
|---|---|
| cytosol | 5 |
| nucleus | 4 |
| extracellular | 2 |
| plasma membrane | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| peroxisome | 1 |
| endosome | 1 |
| lysosome | 1 |
- Vesicles (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005654 | nucleoplasm | IBA | 21873635 |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005829 | cytosol | TAS | -- |
Pathways & Interactions for DTX4 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Cytosolic sensors of pathogen-associated DNA | ||
| 2 | Notch Signaling Pathway (WikiPathways) | ||
| 3 | Innate Immune System |
.61
|
|
| 4 | Signaling by NOTCH1 | ||
| 5 | NOTCH2 Activation and Transmission of Signal to the Nucleus | ||
Pathways by source for DTX4 Gene
2 BioSystems pathways for DTX4 Gene
1 KEGG pathway for DTX4 Gene
1 GeneTex pathway for DTX4 Gene
UniProtKB/Swiss-Prot Q9Y2E6-DTX4_HUMAN
- Pathway: Protein modification; protein ubiquitination.
Interacting Proteins for DTX4 Gene
GPS-Prot Interaction Network for DTX4
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007219 | Notch signaling pathway | IBA | 21873635 |
| GO:0016567 | protein ubiquitination | IBA,IEA | -- |
| GO:0032479 | regulation of type I interferon production | TAS | -- |
Transcripts for DTX4 Gene
mRNA/cDNA for DTX4 Gene
- 2 REFSEQ mRNAs :
- 6 NCBI additional mRNA sequence :
- 4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000227451 6003 nts (view in UCSC)
- ENST00000527475 651 nts (view in UCSC)
- ENST00000531902 494 nts (view in UCSC)
- ENST00000532982 1708 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for DTX4 - Starting at $85 >
- * DTX4 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for DTX4
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for DTX4
-
Santa Cruz Biotechnology (SCBT) CRISPR for DTX4
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for DTX4
- Browse OriGene Inhibitory RNA Products For DTX4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for DTX4
Clone products for research
- Applied Biological Materials (abm): Clones for DTX4 - Starting at $45 >
- * DTX4 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for DTX4
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for DTX4
Relevant External Links for DTX4 Gene
- GeneLoc Exon Structure for
- DTX4
Expression for DTX4 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
- Neural Tube (Nervous System)
-
Spinal Cord (Nervous System)
-
Heart (Cardiovascular System)
mRNA differential expression in normal tissues according to GTEx for DTX4 Gene
This gene is overexpressed in Brain - Spinal cord (cervical c-1) (x4.7).
This gene is overexpressed in Pancreatic juice (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for DTX4 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for DTX4
SOURCE GeneReport for Unigene cluster for DTX4 Gene:
Hs.523696Evidence on tissue expression from TISSUES for DTX4 Gene
- Nervous system(4.6)
Primer products for research
-
OriGene qPCR primer pairs for DTX4
-
OriGene qPCR primer pairs and template standards for DTX4
Gene Expression Assays for research
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for DTX4 Gene
Orthologs for DTX4 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | DTX4 30 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | DTX4 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | DTX4 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Dtx4 30 |
|
||
| Cow (Bos Taurus) |
Mammalia | DTX4 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Dtx4 30 17 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | DTX4 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | DTX4 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | DTX4 31 |
|
OneToOne | |
| Zebrafish (Danio rerio) |
Actinopterygii | dtx1 30 |
|
||
| DTX4 (1 of 2) 31 |
|
OneToMany | |||
| DTX4 (2 of 2) 31 |
|
OneToMany | |||
| Fruit Fly (Drosophila melanogaster) |
Insecta | dx 31 |
|
OneToMany | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.7641 31 |
|
OneToMany |
- Species where no ortholog for DTX4 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for DTX4 Gene
- ENSEMBL:
- Gene Tree for DTX4 (if available)
- TreeFam:
- Gene Tree for DTX4 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for DTX4: view image
Paralogs for DTX4 Gene
Variants for DTX4 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for DTX4 Gene
| SNP ID | Clinical significance and condition | Chr 11 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs2275991 | Benign: not provided | 59,189,229(+) |
C/T NM_015177.2(DTX4):c.1065C>T (p.Val355=) |
SYNONYMOUS | |
| rs61736707 | Benign: not provided | 59,189,190(+) |
G/A NM_015177.2(DTX4):c.1026G>A (p.Ala342=) |
SYNONYMOUS | |
| rs61744443 | Benign: not provided | 59,182,297(+) |
T/G NM_015177.2(DTX4):c.770T>G (p.Val257Gly) |
MISSENSE | |
| rs75403375 | Benign: not provided | 59,182,379(+) |
C/T NM_015177.2(DTX4):c.852C>T (p.Thr284=) |
SYNONYMOUS |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2759830 | CNV | gain | 17122850 |
| nsv1050013 | CNV | gain | 25217958 |
Residual Variation Intolerance Score:
15.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.58;
30.56% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for DTX4 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- DTX4
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for DTX4 Gene
Disorders for DTX4 Gene
Additional Disease Information for DTX4
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No disorders were found for DTX4 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for DTX4 Gene
Publications for DTX4 Gene
- NLRP4 negatively regulates type I interferon signaling by targeting the kinase TBK1 for degradation via the ubiquitin ligase DTX4. (PMID: 22388039) Cui J … Wang RF (Nature immunology 2012) 2 3 4
- Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10231032) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 1999) 2 3 4
- Normal immune system development in mice lacking the Deltex-1 RING finger domain. (PMID: 15684394) Storck S … Reynaud CA (Molecular and cellular biology 2005) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- DELTEX2 C-terminal domain recognizes and recruits ADP-ribosylated proteins for ubiquitination. (PMID: 32937373) Ahmed SF … Huang DT (Science advances 2020) 3
ExternalLinks
Products for DTX4 Gene
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for DTX4
- Search Origene for MassSpec and Protein Over-expression Lysates for DTX4
- Origene Custom Protein Services for DTX4
- Origene shrna, sirna, and RNAi products in human, mouse, rat for DTX4
- Browse OriGene Inhibitory RNA Products For DTX4
- OriGene qPCR primer pairs for DTX4
- OriGene qPCR primer pairs and template standards for DTX4
- OriGene CRISPR knockouts for DTX4
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For DTX4
- Sino Biological Human cDNA Clone for DTX4
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for DTX4
- Novus Biologicals proteins for DTX4
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for DTX4 (AFLGC-DTX4)
- VectorBuilder Custom and pre-made DNA vectors for DTX4 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for DTX4 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for DTX4 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for DTX4 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for DTX4
- antibodies-online: Show 10 available Deltex Homolog 4 Antibodies ranked by validation data
- Compare Top Deltex Homolog 4 Antibodies
- antibodies-online: Search results for available Deltex Homolog 4 related products ranked by validation data
- antibodies-online: Show 2 available Deltex Homolog 4 Proteins ranked by validation data
- Compare Top Deltex Homolog 4 Proteins
- Custom Antibody ServicesProSci Antibodies for DTX4
- Search for DTX4 Proteins at ProSci
- Horizon Cell Lines for DTX4
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for DTX4
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for DTX4
- Search GeneCopoeia for miRNA 3'UTR Target clone products for DTX4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for DTX4
- Boster Bio Antibodies for DTX4
- Browse Boster Bio ELISA Kits
Sources for DTX4 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
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