The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemm... See more...

Aliases for DTNA Gene

Aliases for DTNA Gene

  • Dystrobrevin Alpha 2 3 4 5
  • Dystrophin-Related Protein 3 2 3 4
  • DRP3 2 3 4
  • D18S892E 2 3
  • DTN-A 3 4
  • DTN 2 3
  • Dystrobrevin, Alpha 2
  • Alpha-Dystrobrevin 4
  • LVNC1 3
  • DTN-1 2
  • DTN-2 2
  • DTN-3 2
  • DTNA 5

External Ids for DTNA Gene

Previous GeneCards Identifiers for DTNA Gene

  • GC18P032206
  • GC18P031892
  • GC18P030325
  • GC18P030327
  • GC18P032073
  • GC18P028932

Summaries for DTNA Gene

Entrez Gene Summary for DTNA Gene

  • The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

GeneCards Summary for DTNA Gene

DTNA (Dystrobrevin Alpha) is a Protein Coding gene. Diseases associated with DTNA include Left Ventricular Noncompaction 1 and Left Ventricular Noncompaction. Among its related pathways are Muscular Dystrophies and Dystrophin-Glycoprotein Complex. Gene Ontology (GO) annotations related to this gene include calcium ion binding and PDZ domain binding. An important paralog of this gene is DTNB.

UniProtKB/Swiss-Prot Summary for DTNA Gene

  • May be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors.

Gene Wiki entry for DTNA Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for DTNA Gene

Genomics for DTNA Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for DTNA Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH18J034706 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 611.8 +216.2 216166 5.1 CEBPG PRDM10 FOXA1 PRDM1 RFX1 ZSCAN4 POLR2A CEBPA CEBPB JUND DTNA MAPRE2 NOL4 piR-32214-304 HE856242 lnc-MAPRE2-4
GH18J034492 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE CraniofacialAtlas 600.7 +0.8 849 2.9 HNRNPL CREB1 GATAD2A ATF7 PRDM10 ZNF629 ZNF692 FOXA1 LARP7 PRDM1 DTNA lnc-MAPRE2-4 lnc-NOL4-6 ZNF397 ZSCAN30 piR-55284-004 MAPRE2
GH18J034591 Promoter/Enhancer 1.7 EPDnew Ensembl ENCODE CraniofacialAtlas 600.1 +100.1 100051 4.1 PRDM1 POLR2A TCF12 ZNF341 RELB ZSCAN5C ZBTB17 NR2F1 ZFP37 MTA2 DTNA ZSCAN30 RPL10AP13 HSALNG0120838 lnc-MAPRE2-4 MAPRE2
GH18J034818 Promoter 0.7 EPDnew Ensembl 600.1 +324.9 324911 0.4 RF01061-075 DTNA piR-50443-180 MAPRE2 lnc-MAPRE2-4
GH18J034491 Enhancer 0.7 Ensembl 600.7 -1.4 -1389 0.2 PRDM1 ZIC2 ZNF792 TCF7L2 ZXDB OSR2 ZNF580 OVOL3 ZNF189 PRDM4 DTNA lnc-MAPRE2-4 lnc-NOL4-6 RF01045-059 NOL4
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around DTNA on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for DTNA

Top Transcription factor binding sites by QIAGEN in the DTNA gene promoter:
  • aMEF-2
  • AREB6
  • c-Myc
  • HOXA9
  • Max1
  • MEF-2A
  • PPAR-gamma1
  • PPAR-gamma2
  • STAT5A
  • USF1

Genomic Locations for DTNA Gene

Genomic Locations for DTNA Gene
chr18:34,493,290-34,891,844
(GRCh38/hg38)
Size:
398,555 bases
Orientation:
Plus strand
chr18:32,073,254-32,471,808
(GRCh37/hg19)
Size:
398,555 bases
Orientation:
Plus strand

Genomic View for DTNA Gene

Genes around DTNA on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DTNA Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DTNA Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DTNA Gene

Proteins for DTNA Gene

  • Protein details for DTNA Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9Y4J8-DTNA_HUMAN
    Recommended name:
    Dystrobrevin alpha
    Protein Accession:
    Q9Y4J8
    Secondary Accessions:
    • A8K541
    • A8MSZ0
    • A8MUY4
    • B4DGS6
    • B4DIR0
    • B4DIU8
    • M0QYX6
    • M0R397
    • O15332
    • O15333
    • O75697
    • Q13197
    • Q13198
    • Q13199
    • Q13498
    • Q13499
    • Q13500
    • Q59GK7
    • Q9BS59

    Protein attributes for DTNA Gene

    Size:
    743 amino acids
    Molecular mass:
    83901 Da
    Quaternary structure:
    • Interacts with dystrophin, utrophin and the syntrophins SNTA1, SNTB1, SNTB2, SNTG1 and SNTG2. Isoform 7 and isoform 8 do not interact with dystrophin. Binds dystrobrevin binding protein 1. Interacts with MAGEE1 (By similarity).
    SequenceCaution:
    • Sequence=BAD92339.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for DTNA Gene

neXtProt entry for DTNA Gene

Post-translational modifications for DTNA Gene

  • Phosphorylation of DTN-1 on tyrosine kinase substrate domain present in the C-terminus.
  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for DTNA Gene

Domains & Families for DTNA Gene

Gene Families for DTNA Gene

HGNC:
Human Protein Atlas (HPA):
  • Disease related genes
  • Plasma proteins
  • Predicted intracellular proteins
  • Predicted membrane proteins

Protein Domains for DTNA Gene

InterPro:
Blocks:
  • Zn-finger, ZZ type
ProtoNet:

Suggested Antigen Peptide Sequences for DTNA Gene

GenScript: Design optimal peptide antigens:
  • cDNA FLJ77455, highly similar to Homo sapiens dystrobrevin, alpha (DTNA), transcript variant 5, mRNA (A8K541_HUMAN)
  • cDNA FLJ53338, highly similar to Dystrobrevin alpha (B4DIR0_HUMAN)
  • Alpha-dystrobrevin (D2DGW5_HUMAN)
  • Alpha-dystrobrevin (D2DGW6_HUMAN)
  • Dystrophin-related protein 3 (DTNA_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q9Y4J8

UniProtKB/Swiss-Prot:

DTNA_HUMAN :
  • The coiled coil domain mediates the interaction with dystrophin and utrophin.
  • Belongs to the dystrophin family. Dystrobrevin subfamily.
Domain:
  • The coiled coil domain mediates the interaction with dystrophin and utrophin.
Family:
  • Belongs to the dystrophin family. Dystrobrevin subfamily.
genes like me logo Genes that share domains with DTNA: view

Function for DTNA Gene

Molecular function for DTNA Gene

UniProtKB/Swiss-Prot Function:
May be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors.
GENATLAS Biochemistry:
dystrobrevin alpha,87kDa,cytoplasmic,dystrophin related phosphoprotein,found at the Torpedo electric organ post-synaptic membrane,involved in the formation and stability of the synapses,component of the dystrophin glycoprotein complex,with dystrophin and syntrophins

Phenotypes From GWAS Catalog for DTNA Gene

Gene Ontology (GO) - Molecular Function for DTNA Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 11353857
GO:0008270 zinc ion binding IEA --
GO:0030165 PDZ domain binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with DTNA: view
genes like me logo Genes that share phenotypes with DTNA: view

Human Phenotype Ontology for DTNA Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for DTNA Gene

MGI Knock Outs for DTNA:

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for DTNA

Clone Products

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for DTNA Gene

Localization for DTNA Gene

Subcellular locations from UniProtKB/Swiss-Prot for DTNA Gene

Cytoplasm. Cell junction, synapse. Cell membrane. Note=In peripheral nerves, colocalizes with MAGEE1 in the Schwann cell membrane. {ECO:0000250}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for DTNA gene
Compartment Confidence
plasma membrane 3
nucleus 3
extracellular 2
cytoskeleton 2
cytosol 2
mitochondrion 1
endoplasmic reticulum 1
endosome 1
lysosome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cell Junctions (3)
  • Intermediate filaments (2)
  • Nucleoplasm (1)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for DTNA Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
GO:0005886 plasma membrane IEA,IBA 21873635
GO:0016020 membrane IEA --
GO:0030054 cell junction IEA --
GO:0030424 axon IEA --
genes like me logo Genes that share ontologies with DTNA: view

Pathways & Interactions for DTNA Gene

PathCards logo

SuperPathways for DTNA Gene

SuperPathway Contained pathways
1 Muscular Dystrophies and Dystrophin-Glycoprotein Complex
-
genes like me logo Genes that share pathways with DTNA: view

Pathways by source for DTNA Gene

1 Qiagen pathway for DTNA Gene
  • Muscular Dystrophies and Dystrophin-Glycoprotein Complex

Gene Ontology (GO) - Biological Process for DTNA Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006941 striated muscle contraction TAS 10767327
GO:0007165 signal transduction TAS 10767327
GO:0007268 chemical synaptic transmission TAS 8845841
GO:0007274 neuromuscular synaptic transmission TAS 9119373
GO:0099536 synaptic signaling IBA 21873635
genes like me logo Genes that share ontologies with DTNA: view

No data available for SIGNOR curated interactions for DTNA Gene

Drugs & Compounds for DTNA Gene

No Compound Related Data Available

Transcripts for DTNA Gene

mRNA/cDNA for DTNA Gene

17 REFSEQ mRNAs :
40 NCBI additional mRNA sequence :
35 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for DTNA

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for DTNA Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22a · 22b ^ 23 ^ 24 ^
SP1: - - - - - -
SP2: -
SP3: - - - -
SP4: - -
SP5:
SP6:

ExUns: 25 ^ 26a · 26b ^ 27 ^ 28a · 28b · 28c
SP1:
SP2:
SP3:
SP4:
SP5:
SP6: - -

Relevant External Links for DTNA Gene

GeneLoc Exon Structure for
DTNA

Expression for DTNA Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for DTNA Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for DTNA Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (x4.6) and Brain - Amygdala (x4.1).

Protein differential expression in normal tissues from HIPED for DTNA Gene

This gene is overexpressed in Urinary Bladder (11.0), Heart (9.2), Prostate (7.6), and Cerebrospinal fluid (7.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for DTNA Gene



Protein tissue co-expression partners for DTNA Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for DTNA

SOURCE GeneReport for Unigene cluster for DTNA Gene:

Hs.643454

mRNA Expression by UniProt/SwissProt for DTNA Gene:

Q9Y4J8-DTNA_HUMAN
Tissue specificity: Highly expressed in brain, skeletal and cardiac muscles, and expressed at lower levels in lung, liver and pancreas. Isoform 2 is not expressed in cardiac muscle. Isoform 7 and isoform 8 are only expressed in muscle.

Evidence on tissue expression from TISSUES for DTNA Gene

  • Nervous system(5)
  • Heart(4.6)
  • Muscle(3.4)
  • Eye(2)

Phenotype-based relationships between genes and organs from Gene ORGANizer for DTNA Gene

Germ Layers:
  • endoderm
  • mesoderm
Systems:
  • cardiovascular
  • respiratory
Regions:
Head and neck:
  • ear
Thorax:
  • heart
  • heart valve
  • lung
General:
  • blood
  • blood vessel
genes like me logo Genes that share expression patterns with DTNA: view

Orthologs for DTNA Gene

This gene was present in the common ancestor of animals.

Orthologs for DTNA Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia DTNA 30 31
  • 99.69 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia DTNA 30 31
  • 93.02 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia DTNA 30 31
  • 92.01 (n)
OneToOne
Mouse
(Mus musculus)
Mammalia Dtna 30 17 31
  • 90.44 (n)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia DTNA 31
  • 90 (a)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Dtna 30
  • 89.81 (n)
Platypus
(Ornithorhynchus anatinus)
Mammalia DTNA 31
  • 87 (a)
OneToOne
Chicken
(Gallus gallus)
Aves DTNA 30 31
  • 84.62 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia DTNA 31
  • 81 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia dyb-1 30
  • 79.84 (n)
African clawed frog
(Xenopus laevis)
Amphibia dtna-A 30
Zebrafish
(Danio rerio)
Actinopterygii dtna 30 31
  • 69.76 (n)
OneToOne
Fruit Fly
(Drosophila melanogaster)
Insecta Dyb 31
  • 36 (a)
OneToMany
Worm
(Caenorhabditis elegans)
Secernentea dyb-1 31 32
  • 44 (a)
OneToMany
Sea Squirt
(Ciona savignyi)
Ascidiacea -- 31
  • 12 (a)
OneToMany
Species where no ortholog for DTNA was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)

Evolution for DTNA Gene

ENSEMBL:
Gene Tree for DTNA (if available)
TreeFam:
Gene Tree for DTNA (if available)
Aminode:
Evolutionary constrained regions (ECRs) for DTNA: view image

Paralogs for DTNA Gene

(3) SIMAP similar genes for DTNA Gene using alignment to 18 proteins:

  • DTNA_HUMAN
  • A8K541_HUMAN
  • D2DGW5_HUMAN
  • D2DGW6_HUMAN
  • F8WE01_HUMAN
  • K7EIV1_HUMAN
  • K7EJ84_HUMAN
  • K7EMN1_HUMAN
  • K7ENJ7_HUMAN
  • K7ER73_HUMAN
  • K7ERH7_HUMAN
  • K7ERZ2_HUMAN
  • K7ESB2_HUMAN
  • L8E9H2_HUMAN
  • M0QYX6_HUMAN
  • M0QZ28_HUMAN
  • M0R021_HUMAN
  • M0R0C4_HUMAN
genes like me logo Genes that share paralogs with DTNA: view

Variants for DTNA Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for DTNA Gene

SNP ID Clinical significance and condition Chr 18 pos Variation AA Info Type
140609 Likely Pathogenic: Ménière's disease 34,882,130(+) G/T MISSENSE_VARIANT
639120 Uncertain Significance: Left ventricular noncompaction 1 34,851,880(+) C/T MISSENSE_VARIANT
640747 Uncertain Significance: Left ventricular noncompaction 1 34,794,076(+) G/A MISSENSE_VARIANT
641320 Uncertain Significance: Left ventricular noncompaction 1 34,858,350(+) A/G MISSENSE_VARIANT
652072 Uncertain Significance: Left ventricular noncompaction 1 34,858,389(+) G/A MISSENSE_VARIANT

Additional dbSNP identifiers (rs#s) for DTNA Gene

Structural Variations from Database of Genomic Variants (DGV) for DTNA Gene

Variant ID Type Subtype PubMed ID
dgv977e212 CNV loss 25503493
esv2663213 CNV deletion 23128226
esv2672684 CNV deletion 23128226
esv2677908 CNV deletion 23128226
esv3555216 CNV deletion 23714750
esv3642190 CNV loss 21293372
nsv1118786 CNV deletion 24896259
nsv1139684 CNV duplication 24896259
nsv131325 CNV deletion 16902084
nsv2251 CNV insertion 18451855
nsv516464 CNV loss 19592680
nsv525306 CNV loss 19592680

Variation tolerance for DTNA Gene

Residual Variation Intolerance Score: 22% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.09; 38.21% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for DTNA Gene

Human Gene Mutation Database (HGMD)
DTNA
SNPedia medical, phenotypic, and genealogical associations of SNPs for
DTNA

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for DTNA Gene

Disorders for DTNA Gene

MalaCards: The human disease database

(18) MalaCards diseases for DTNA Gene - From: OMIM, ClinVar, GTR, Orphanet, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
left ventricular noncompaction 1
  • lvnc1
left ventricular noncompaction
  • left ventricular hypertrabeculation
barth syndrome
  • bths
meniere disease
  • meniere's disease
muscular dystrophy
  • muscular dystrophies
- elite association - COSMIC cancer census association via MalaCards
Search DTNA in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

DTNA_HUMAN
  • Left ventricular non-compaction 1 (LVNC1) [MIM:604169]: A form of left ventricular non-compaction, a cardiomyopathy due to myocardial morphogenesis arrest and characterized by a hypertrophic left ventricle, a severely thickened 2-layered myocardium, numerous prominent trabeculations, deep intertrabecular recesses, and poor systolic function. Clinical manifestations are variable. Some affected individuals experience no symptoms at all, others develop heart failure. In some cases, left ventricular non-compaction is associated with other congenital heart anomalies. LVNC1 is an autosomal dominant condition. {ECO:0000269 PubMed:11238270}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Additional Disease Information for DTNA

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
genes like me logo Genes that share disorders with DTNA: view

No data available for Genatlas for DTNA Gene

Publications for DTNA Gene

  1. Association of alpha-dystrobrevin with reorganizing tight junctions. (PMID: 15834686) Sjö A … Peterson KH (The Journal of membrane biology 2005) 2 3 23
  2. Deficiency of the syntrophins and alpha-dystrobrevin in patients with inherited myopathy. (PMID: 12899872) Jones KJ … North KN (Neuromuscular disorders : NMD 2003) 3 23 41
  3. Novel gene mutations in patients with left ventricular noncompaction or Barth syndrome. (PMID: 11238270) Ichida F … Towbin JA (Circulation 2001) 3 4 23
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 41
  5. Profound human/mouse differences in alpha-dystrobrevin isoforms: a novel syntrophin-binding site and promoter missing in mouse and rat. (PMID: 19961569) Böhm SV … Roberts RG (BMC biology 2009) 3 23

Products for DTNA Gene

Sources for DTNA Gene