Aliases for DSG2-AS1 Gene

Data sources for DSG2-AS1 Gene:

Subcategory (RNA class) for DSG2-AS1 Gene

lncRNA

Aliases for DSG2-AS1 Gene

External Ids for DSG2-AS1 Gene

Summaries for DSG2-AS1 Gene

GeneCards Summary for DSG2-AS1 Gene

DSG2-AS1 (DSG2 Antisense RNA 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with DSG2-AS1 include Cardiomyopathy, Dilated, 1Bb and Arrhythmogenic Right Ventricular Dysplasia, Familial, 10.

Additional gene information for DSG2-AS1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for DSG2-AS1 Gene

Genomics for DSG2-AS1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for DSG2-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH18J031555 Enhancer 0.8 Ensembl ENCODE 250.7 +0.8 820 0.6 CTCF REST TRIM22 SMC3 RAD21 ZNF189 RB1 ZNF362 ZNF384 ZNF143 DSG2-AS1 TTR B4GALT6 TRAPPC8 ENSG00000266521 HSALNG0120734 DSG2
GH18J031554 Enhancer 0.5 Ensembl 250.7 +1.9 1947 0.4 RXRA REST SP1 HNF4A YY1 DSG2-AS1 B4GALT6 TRAPPC8 TTR HSALNG0120734 DSG2
GH18J031556 Promoter 0.3 EPDnew 250.7 0.0 -20 0.1 DSG2-AS1 TTR B4GALT6 TRAPPC8 DSG2
GH18J031510 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 0.3 +45.3 45322 6 MXD4 CEBPA FOXA1 MNT BHLHE40 CTCF HOMEZ KDM6A THAP11 CEBPB HSALNG0120734 ENSG00000266521 B4GALT6 DSG2 DSC3 DSG1 DSC2 DSG2-AS1 TTR
GH18J031549 Enhancer 0.6 Ensembl ENCODE 0.4 +7.4 7447 1 RBM22 PRDM6 PKNOX1 PHF21A DSG2-AS1 TTR HSALNG0120734 DSG2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around DSG2-AS1 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for DSG2-AS1 Gene

Latest Assembly
chr18:31,540,305-31,556,948
(GRCh38/hg38)
Size:
16,644 bases
Orientation:
Minus strand

Previous Assembly
chr18:29,122,109-29,136,874
(GRCh37/hg19 by Entrez Gene)
Size:
14,766 bases
Orientation:
Minus strand

chr18:29,122,109-29,136,874
(GRCh37/hg19 by Ensembl)
Size:
14,766 bases
Orientation:
Minus strand

Genomic View for DSG2-AS1 Gene

Genes around DSG2-AS1 on UCSC Golden Path with GeneCards custom track
DSG2-AS1 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
DSG2-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DSG2-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DSG2-AS1 Gene

Proteins for DSG2-AS1 Gene

Post-translational modifications for DSG2-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for DSG2-AS1 Gene

Domains & Families for DSG2-AS1 Gene

Gene Families for DSG2-AS1 Gene

genes like me logo Genes that share domains with DSG2-AS1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for DSG2-AS1 Gene

Function for DSG2-AS1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for DSG2-AS1 Gene

Localization for DSG2-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for DSG2-AS1 Gene

Pathways & Interactions for DSG2-AS1 Gene

PathCards logo

SuperPathways for DSG2-AS1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for DSG2-AS1 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for DSG2-AS1 Gene

Drugs & Compounds for DSG2-AS1 Gene

No Compound Related Data Available

Transcripts for DSG2-AS1 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for DSG2-AS1 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS00005DB14C_9606 lncRNA 814 4

Ensembl: ENST00000579251 (view in UCSC) ,

LncBook: HSALNT0249615,

LNCipedia: DSG2-AS1:4,

NONCODE: NONHSAT058826.2,

URS00002283A5_9606 lncRNA 2030 3

Ensembl: ENST00000583706 (view in UCSC) ,

LNCipedia: DSG2-AS1:2,

NONCODE: NONHSAT058823.2,

URS000075E03B_9606 lncRNA 1986 1

RefSeq: NR_045216,

URS0000EEC028_9606 lncRNA 1254 1

Ensembl: ENST00000657343 (view in UCSC) ,

URS0000EF3402_9606 lncRNA 1209 1

Ensembl: ENST00000664179 (view in UCSC) ,

DSG2-AS1 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for DSG2-AS1 Gene

1 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for DSG2-AS1 Gene

No ASD Table

Relevant External Links for DSG2-AS1 Gene

GeneLoc Exon Structure for
DSG2-AS1

Expression for DSG2-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for DSG2-AS1 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for DSG2-AS1

genes like me logo Genes that share expression patterns with DSG2-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for DSG2-AS1 Gene

Orthologs for DSG2-AS1 Gene

Evolution for DSG2-AS1 Gene

ENSEMBL:
Gene Tree for DSG2-AS1 (if available)
TreeFam:
Gene Tree for DSG2-AS1 (if available)

No data available for Orthologs for DSG2-AS1 Gene

Paralogs for DSG2-AS1 Gene

No data available for Paralogs for DSG2-AS1 Gene

Variants for DSG2-AS1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for DSG2-AS1 Gene

SNP ID Clinical significance and condition Chr 18 pos Variation AA Info Type
835133 Uncertain Significance: Arrhythmogenic right ventricular cardiomyopathy, type 10 31,546,216(-) T/C
NM_001943.5(DSG2):c.2830T>C (p.Ser944Pro)
MISSENSE
835215 Pathogenic: Arrhythmogenic right ventricular cardiomyopathy, type 10 31,546,003(-) CA/C
NM_001943.5(DSG2):c.2620del (p.Thr874fs)
FRAMESHIFT
835821 Uncertain Significance: Arrhythmogenic right ventricular cardiomyopathy, type 10 31,546,666(-) G/C
NM_001943.5(DSG2):c.3280G>C (p.Gly1094Arg)
MISSENSE
835905 Conflicting Interpretations: Cardiomyopathy; Arrhythmogenic right ventricular cardiomyopathy, type 10 31,546,591(-) A/G
NM_001943.5(DSG2):c.3205A>G (p.Met1069Val)
MISSENSE
836109 Uncertain Significance: Arrhythmogenic right ventricular cardiomyopathy, type 10 31,545,833(-) T/A
NM_001943.5(DSG2):c.2447T>A (p.Phe816Tyr)
MISSENSE_VARIANT,NON_CODING_TRANSCRIPT

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for DSG2-AS1 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for DSG2-AS1 Gene

Variant ID Type Subtype PubMed ID
nsv576635 CNV gain 21841781
nsv833615 CNV gain 17160897

Additional Variant Information for DSG2-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
DSG2-AS1

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for DSG2-AS1 Gene

Disorders for DSG2-AS1 Gene

MalaCards: The human disease database

(7) MalaCards diseases for DSG2-AS1 Gene - From: CVR and GCD

Disorder Aliases PubMed IDs
cardiomyopathy, dilated, 1bb
  • cmd1bb
arrhythmogenic right ventricular dysplasia, familial, 10
  • arvd10
dilated cardiomyopathy
  • congestive cardiomyopathy
familial isolated dilated cardiomyopathy
  • familial or idiopathic dilated cardiomyopathy
arrhythmogenic right ventricular cardiomyopathy
  • arrhythmogenic right ventricular dysplasia
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for DSG2-AS1

genes like me logo Genes that share disorders with DSG2-AS1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for DSG2-AS1 Gene

Publications for DSG2-AS1 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3

Products for DSG2-AS1 Gene

Sources for DSG2-AS1 Gene