Aliases for DSCAM-AS1 Gene

Subcategory (RNA class) for DSCAM-AS1 Gene

lncRNA

Quality Score for this RNA gene is

15

Aliases for DSCAM-AS1 Gene

  • DSCAM Antisense RNA 1 2 3 5
  • DSCAM Antisense RNA 1 (Non-Protein Coding) 2 3
  • DSCAM-AS1 2 170
  • NONHSAG032888 94
  • HSALNG0133168 169
  • M41 3

External Ids for DSCAM-AS1 Gene

Previous GeneCards Identifiers for DSCAM-AS1 Gene

  • GC21P041757

Summaries for DSCAM-AS1 Gene

GeneCards Summary for DSCAM-AS1 Gene

DSCAM-AS1 (DSCAM Antisense RNA 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with DSCAM-AS1 include Idiopathic Scoliosis and Breast Cancer.

Additional gene information for DSCAM-AS1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for DSCAM-AS1 Gene

Genomics for DSCAM-AS1 Gene

GeneHancer (GH) Regulatory Elements for DSCAM-AS1 Gene

Promoters and enhancers for DSCAM-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH21J040380 Enhancer 0.8 dbSUPER 750.6 -1.0 -985 2.2 E2F8 GATA3 SREBF1 TCF7L2 ZNF217 MNT MTA3 NCOA3 MYC POLR2A DSCAM-AS1 piR-30791-060 DSCAM
GH21J040383 Enhancer 0.8 dbSUPER 750.6 +0.8 808 1.2 PPP1R10 SREBF1 ZNF217 MNT MYC POLR2A HDGF FOSL2 CREB1 GATAD2B DSCAM-AS1 LOC105369294 DSCAM
GH21J040343 Enhancer 0.3 dbSUPER 12.3 -37.9 -37931 2.4 CREB1 POLR2A DSCAM-AS1 piR-30791-060 DSCAM
GH21J040384 Enhancer 0.9 Ensembl dbSUPER 0.6 +3.2 3153 0.4 PPP1R10 ZNF785 CTCF SREBF1 TCF7L2 ZNF217 MNT MTA3 POLR2A EGR1 ENSG00000207147 DSCAM-AS1 LOC105369294 DSCAM
GH21J040378 Enhancer 0.5 dbSUPER 0.6 -3.2 -3206 2.1 ZKSCAN1 ZNF207 GATA3 ZNF687 JUND DSCAM-AS1 piR-30791-060 DSCAM
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around DSCAM-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for DSCAM-AS1 Gene

Genomic Locations for DSCAM-AS1 Gene
chr21:40,383,048-40,385,359
(GRCh38/hg38)
Size:
2,312 bases
Orientation:
Plus strand
chr21:41,755,010-41,757,285
(GRCh37/hg19)
Size:
2,276 bases
Orientation:
Plus strand

Genomic View for DSCAM-AS1 Gene

Genes around DSCAM-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
DSCAM-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for DSCAM-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for DSCAM-AS1 Gene

Proteins for DSCAM-AS1 Gene

Post-translational modifications for DSCAM-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for DSCAM-AS1 Gene

Domains & Families for DSCAM-AS1 Gene

Gene Families for DSCAM-AS1 Gene

genes like me logo Genes that share domains with DSCAM-AS1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for DSCAM-AS1 Gene

Function for DSCAM-AS1 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for DSCAM-AS1 Gene

Localization for DSCAM-AS1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for DSCAM-AS1 gene
Compartment Confidence
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for DSCAM-AS1 Gene

Pathways & Interactions for DSCAM-AS1 Gene

PathCards logo

SuperPathways for DSCAM-AS1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for DSCAM-AS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for DSCAM-AS1 Gene

Drugs & Compounds for DSCAM-AS1 Gene

No Compound Related Data Available

Transcripts for DSCAM-AS1 Gene

mRNA/cDNA for DSCAM-AS1 Gene

(4) REFSEQ mRNAs :
(8) Additional mRNA sequences :
(4) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(9) RNACentral transcripts :
(7) LNCipedia transcripts :
(6) NONCODE transcripts :
(3) LncBook transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for DSCAM-AS1 Gene

No ASD Table

Relevant External Links for DSCAM-AS1 Gene

GeneLoc Exon Structure for
DSCAM-AS1
ECgene alternative splicing isoforms for
DSCAM-AS1

Expression for DSCAM-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for DSCAM-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for DSCAM-AS1 Gene

This gene is overexpressed in Prostate (x46.0).

SOURCE GeneReport for Unigene cluster for DSCAM-AS1 Gene:

Hs.667053
genes like me logo Genes that share expression patterns with DSCAM-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for DSCAM-AS1 Gene

Orthologs for DSCAM-AS1 Gene

Evolution for DSCAM-AS1 Gene

ENSEMBL:
Gene Tree for DSCAM-AS1 (if available)
TreeFam:
Gene Tree for DSCAM-AS1 (if available)

No data available for Orthologs for DSCAM-AS1 Gene

Paralogs for DSCAM-AS1 Gene

No data available for Paralogs for DSCAM-AS1 Gene

Variants for DSCAM-AS1 Gene

Sequence variations from dbSNP and Humsavar for DSCAM-AS1 Gene

SNP ID Clin Chr 21 pos Variation AA Info Type
rs1000587885 -- 40,382,028(+) G/C upstream_transcript_variant
rs1001014630 -- 40,381,645(+) T/A upstream_transcript_variant
rs1001407202 -- 40,381,228(+) T/G upstream_transcript_variant
rs1002388786 -- 40,382,238(+) G/A/C upstream_transcript_variant
rs1002421315 -- 40,382,463(+) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for DSCAM-AS1 Gene

Variant ID Type Subtype PubMed ID
nsv520586 CNV loss 19592680
nsv528658 CNV loss 19592680
nsv834100 CNV gain 17160897

Additional Variant Information for DSCAM-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
DSCAM-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for DSCAM-AS1 Gene

Disorders for DSCAM-AS1 Gene

MalaCards: The human disease database

(2) MalaCards diseases for DSCAM-AS1 Gene - From: LncRNADisease and DISEASES

Disorder Aliases PubMed IDs
idiopathic scoliosis
  • scoliosis idiopathic
breast cancer
  • breast cancer, familial
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for DSCAM-AS1

genes like me logo Genes that share disorders with DSCAM-AS1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for DSCAM-AS1 Gene

Publications for DSCAM-AS1 Gene

  1. The lncRNA landscape of breast cancer reveals a role for DSCAM-AS1 in breast cancer progression. (PMID: 27666543) Niknafs YS … Feng FY (Nature communications 2016) 2 3 56
  2. DSCAM-AS1 up-regulation in invasive ductal carcinoma of breast and assessment of its potential as a diagnostic biomarker. (PMID: 30594914) Khorshidi H … Ghafouri-Fard S (Breast disease 2019) 3 56
  3. DSCAM-AS1 promotes tumor growth of breast cancer by reducing miR-204-5p and up-regulating RRM2. (PMID: 30457164) Liang WH … Wang ZH (Molecular carcinogenesis 2019) 3 56
  4. Luminal long non-coding RNAs regulated by estrogen receptor alpha in a ligand-independent manner show functional roles in breast cancer. (PMID: 26621851) Miano V … De Bortoli M (Oncotarget 2016) 3 56
  5. Comprehensive characterization of cancer subtype associated long non-coding RNAs and their clinical implications. (PMID: 25307233) Zhao W … Jiao S (Scientific reports 2014) 3 56

Products for DSCAM-AS1 Gene

Sources for DSCAM-AS1 Gene