Aliases for DRG2 Gene
External Ids for DRG2 Gene
Previous GeneCards Identifiers for DRG2 Gene
This gene encodes a GTP-binding protein known to function in the regulation of cell growth and differentiation. Read-through transcripts containing this gene and a downstream gene have been identified, but they are not thought to encode a fusion protein. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jan 2012]
GeneCards Summary for DRG2 Gene
DRG2 (Developmentally Regulated GTP Binding Protein 2) is a Protein Coding gene. Diseases associated with DRG2 include Volkmann Contracture and Smith-Magenis Syndrome. Gene Ontology (GO) annotations related to this gene include GTP binding and ferrous iron transmembrane transporter activity. An important paralog of this gene is DRG1.
UniProtKB/Swiss-Prot Summary for DRG2 Gene
Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. When hydroxylated at C-3 of 'Lys-21' by JMJD7, may bind to RNA and play a role in translation.