Aliases for DRG2 Gene
External Ids for DRG2 Gene
Previous GeneCards Identifiers for DRG2 Gene
This gene encodes a GTP-binding protein known to function in the regulation of cell growth and differentiation. Read-through transcripts containing this gene and a downstream gene have been identified, but they are not thought to encode a fusion protein. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jan 2012]
GeneCards Summary for DRG2 Gene
DRG2 (Developmentally Regulated GTP Binding Protein 2) is a Protein Coding gene. Diseases associated with DRG2 include Smith-Magenis Syndrome and Lung Adenoid Cystic Carcinoma. Gene Ontology (GO) annotations related to this gene include GTP binding and ferrous iron transmembrane transporter activity. An important paralog of this gene is DRG1.
UniProtKB/Swiss-Prot Summary for DRG2 Gene
Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. When hydroxylated at C-3 of 'Lys-21' by JMJD7, may bind to RNA and play a role in translation.