Aliases for DPYSL5 Gene
External Ids for DPYSL5 Gene
Previous GeneCards Identifiers for DPYSL5 Gene
This gene encodes a member of the CRMP (collapsing response mediator protein) family thought to be involved in neural development. Antibodies to the encoded protein were found in some patients with neurologic symptoms who had paraneoplastic syndrome. A pseudogene of this gene is found on chromosome 11. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011]
GeneCards Summary for DPYSL5 Gene
DPYSL5 (Dihydropyrimidinase Like 5) is a Protein Coding gene. Diseases associated with DPYSL5 include Thymoma and Syndrome With A Dandy-Walker Malformation As Major Feature. Among its related pathways are Developmental Biology and Semaphorin Signaling. Gene Ontology (GO) annotations related to this gene include hydrolase activity and hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds. An important paralog of this gene is DPYS.
UniProtKB/Swiss-Prot Summary for DPYSL5 Gene
May have a function in neuronal differentiation and/or axon growth.