Aliases for DPY19L2 Gene
External Ids for DPY19L2 Gene
Previous GeneCards Identifiers for DPY19L2 Gene
The protein encoded by this gene belongs to the dpy-19 family. It is highly expressed in testis, and is required for sperm head elongation and acrosome formation during spermatogenesis. Mutations in this gene are associated with an infertility disorder, spermatogenic failure type 9 (SPGF9). [provided by RefSeq, Dec 2011]
GeneCards Summary for DPY19L2 Gene
DPY19L2 (Dpy-19 Like 2) is a Protein Coding gene. Diseases associated with DPY19L2 include Spermatogenic Failure 9 and Spermatogenic Failure 6. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring glycosyl groups and mannosyltransferase activity. An important paralog of this gene is DPY19L1.
UniProtKB/Swiss-Prot Summary for DPY19L2 Gene
Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins (By similarity). Required during spermatogenesis for sperm head elongation and acrosome formation.