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This gene encodes a nuclear factor that is involved in the maintenance of pluripotency in stem cells and essential for embryogenesis. The encoded protein has a scaffold-attachment factor A/B, acinus and PIAS (SAP) domain that binds DNA and is thought to modify chromatin. Mice with a homozygous knockout of the orthologous gene die during late embryonic development or within hour... See more...
Aliases for DPPA4 Gene
Aliases for DPPA4 Gene
External Ids for DPPA4 Gene
- HGNC: 19200
- Entrez Gene: 55211
- Ensembl: ENSG00000121570
- OMIM: 614125
- UniProtKB: Q7L190
Previous GeneCards Identifiers for DPPA4 Gene
- GC00U909445
- GC03M110365
- GC03M110527
- GC03M109045
- GC03M106419
Summaries for DPPA4 Gene
-
This gene encodes a nuclear factor that is involved in the maintenance of pluripotency in stem cells and essential for embryogenesis. The encoded protein has a scaffold-attachment factor A/B, acinus and PIAS (SAP) domain that binds DNA and is thought to modify chromatin. Mice with a homozygous knockout of the orthologous gene die during late embryonic development or within hours after birth. Knockout embryos are normal in size at embryonic day 18.5 but exhibit skeletal and lung tissue abnormalities. This gene, when mutated, is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers and is thought to play an important role in tumor progression. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]
GeneCards Summary for DPPA4 Gene
DPPA4 (Developmental Pluripotency Associated 4) is a Protein Coding gene. Diseases associated with DPPA4 include Germ Cell And Embryonal Cancer. Among its related pathways are Transcriptional regulation of pluripotent stem cells and Developmental Biology. An important paralog of this gene is DPPA2.
UniProtKB/Swiss-Prot Summary for DPPA4 Gene
-
May be involved in the maintenance of active epigenetic status of target genes. May inhibit differentiation of embryonic cells into a primitive ectoderm lineage.
Additional gene information for DPPA4 Gene
- HGNC(19200)
- Entrez Gene(55211)
- Ensembl(ENSG00000121570)
- OMIM(614125)
- UniProtKB(Q7L190)
- Open Targets Platform(ENSG00000121570)
- Search for DPPA4 at DataMed
- Search for DPPA4 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for DPPA4 Gene
Genomics for DPPA4 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for DPPA4 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH03J109332 | Promoter/Enhancer | 1.8 | EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER | 609.1 | +3.3 | 3255 | 8 | TEAD4 SP1 POLR2A YY1 JUND ETS1 RAD21 SIN3A HNF4A CHD1 | DPPA4 RF00017-4079 lnc-C3orf85-4 lnc-DPPA4-1-002 DPPA2 piR-46831 lnc-DPPA4-1-001 | |
| GH03J109353 | Enhancer | 0.9 | Ensembl ENCODE dbSUPER | 5.1 | -15.8 | -15817 | 5.3 | TEAD4 SP1 POLR2A YY1 NR2F2 SIN3A HNF4A RXRA MAX NANOG | MORC1-AS1 DPPA4 GUCA1C lnc-DPPA4-1-001 lnc-C3orf85-4 | |
| GH03J109325 | Enhancer | 0.3 | ENCODE | 7.4 | +14.0 | 14026 | 0.9 | POLR2A SIN3A | DPPA4 DPPA2 piR-46831 lnc-DPPA4-1-001 | |
| GH03J109372 | Enhancer | 0.4 | Ensembl | 4.7 | -33.1 | -33066 | 0.2 | HNF4A RXRA SP1 | DPPA4 ENSG00000241257 LOC100129989 lnc-C3orf85-4 | |
| GH03J109358 | Enhancer | 0.3 | Ensembl | 5.7 | -19.0 | -18966 | 0.8 | RXRA | DPPA4 lnc-DPPA4-1-001 lnc-C3orf85-4 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around DPPA4 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for DPPA4
- Top Transcription factor binding sites by QIAGEN in the DPPA4 gene promoter:
-
- AML1a
- c-Ets-1
- COUP
- COUP-TF
- HNF-1
- HNF-1A
- Max1
- POU2F1
- POU2F1a
- S8
Genomic Locations for DPPA4 Gene
Genomic Locations for DPPA4 Gene
- chr3:109,326,141-109,339,635
- (GRCh38/hg38)
- Size:
- 13,495 bases
- Orientation:
- Minus strand
- chr3:109,044,988-109,056,419
- (GRCh37/hg19)
- Size:
- 11,432 bases
- Orientation:
- Minus strand
Genomic View for DPPA4 Gene
Genes around DPPA4 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 3q13.13 by HGNC
- 3q13.13 by Entrez Gene
- 3q13.13 by Ensembl
DPPA4 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for DPPA4 Gene
Proteins for DPPA4 Gene
-
Protein details for DPPA4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q7L190-DPPA4_HUMAN
- Recommended name:
- Developmental pluripotency-associated protein 4
- Protein Accession:
- Q7L190
- A8K4M7
- Q9H9N5
- Q9NVI6
Protein attributes for DPPA4 Gene
- Size:
- 304 amino acids
- Molecular mass:
- 33541 Da
- Quaternary structure:
-
- Interacts with DPPA2 (By similarity). Interacts with PCGF1 (PubMed:26687479).
- SequenceCaution:
-
- Sequence=BAA91765.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305}; Sequence=BAB14188.1; Type=Frameshift; Evidence={ECO:0000305};
Protein Expression for DPPA4 Gene
Post-translational modifications for DPPA4 Gene
Other Protein References for DPPA4 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- LifeSpan BioSciences DPPA4 Antibody
- GeneTex Anti-DPPA4 antibody [N1C3]
- Creative Diagnostics Anti-DPPA4 monoclonal antibody
- Creative Biolabs Mouse Anti-DPPA4 Recombinant Antibody (1C3) and Mouse Anti-DPPA4 Recombinant Antibody (2F6)
- Novus Biologicals Antibodies for DPPA4
-
Abcam antibodies for DPPA4
- Invitrogen Antibodies for DPPA4 (AFLGC-DPPA4)
- Sino Biological Antibodies for DPPA4
Protein Products
- Creative Biomart Recombinant Human DPPA4, His-tagged
-
OriGene Purified Proteins for DPPA4
- Search Origene for MassSpec and Protein Over-expression Lysates for DPPA4
- Origene Custom Protein Services for DPPA4
- ProSpec Recombinant Proteins for DPPA4
- antibodies-online: Show 7 available DPPA4 Proteins ranked by validation data
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-
Quality Products:
-
Abcam proteins for DPPA4
Assay Products
- RayBiotech Custom Human DPPA4 ELISA
- antibodies-online: Show 3 available DPPA4 Elisa Kits ranked by validation data
- Compare Top DPPA4 Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for DPPA4 Gene
Domains & Families for DPPA4 Gene
Gene Families for DPPA4 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for DPPA4 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for DPPA4 Gene
- GenScript: Design optimal peptide antigens:
-
- Developmental pluripotency-associated protein 4 (DPPA4_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for DPPA4 Gene
Function for DPPA4 Gene
Molecular function for DPPA4 Gene
- UniProtKB/Swiss-Prot Function:
- May be involved in the maintenance of active epigenetic status of target genes. May inhibit differentiation of embryonic cells into a primitive ectoderm lineage.
Phenotypes From GWAS Catalog for DPPA4 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003682 | chromatin binding | IEA | -- |
| GO:0005515 | protein binding | IPI | 16169070 |
Phenotypes for DPPA4 Gene
- MGI mutant phenotypes for DPPA4:
- inferred from 4 alleles
- GenomeRNAi human phenotypes for DPPA4:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for DPPA4 - Select products 50% OFF >
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-
OriGene CRISPR knockouts for DPPA4
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for DPPA4
-
Santa Cruz Biotechnology (SCBT) CRISPR for DPPA4
miRNA for DPPA4 Gene
- miRTarBase miRNAs that target DPPA4
-
- hsa-miR-26b-5p (MIRT029606)
- hsa-miR-1207-5p (MIRT761257)
- hsa-miR-3190-5p (MIRT765361)
- hsa-miR-3613-3p (MIRT765984)
- hsa-miR-3665 (MIRT766534)
- hsa-miR-3675-3p (MIRT766670)
- hsa-miR-3926 (MIRT767705)
- hsa-miR-4455 (MIRT769195)
- hsa-miR-4684-5p (MIRT770989)
- hsa-miR-4736 (MIRT771806)
- hsa-miR-4763-3p (MIRT772013)
- hsa-miR-490-3p (MIRT772705)
- hsa-miR-548c-3p (MIRT774304)
- hsa-miR-548s (MIRT774496)
- hsa-miR-5589-5p (MIRT774809)
- hsa-miR-609 (MIRT775773)
- hsa-miR-6771-3p (MIRT778613)
- hsa-miR-6772-5p (MIRT778699)
- hsa-miR-6776-5p (MIRT778739)
- hsa-miR-7150 (MIRT781494)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for DPPA4
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Clone Products
- Applied Biological Materials (abm): Clones for DPPA4 - Select products 50% OFF >
- * DPPA4 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
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- Sino Biological Human cDNA Clone for DPPA4
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for DPPA4
Cell Line Products
-
Horizon Cell Lines for DPPA4
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for DPPA4 Gene
Localization for DPPA4 Gene
Subcellular locations from UniProtKB/Swiss-Prot for DPPA4 Gene
- Nucleus. Note=Associated with transcriptionally active chromatin. {ECO:0000250 UniProtKB:Q8CCG4}.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| plasma membrane | 1 |
| extracellular | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| cytosol | 1 |
| golgi apparatus | 1 |
- Cytosol (2)
- Nucleoli (2)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0005654 | nucleoplasm | TAS | -- |
Pathways & Interactions for DPPA4 Gene
Pathways by source for DPPA4 Gene
3 Reactome pathways for DPPA4 Gene
Interacting Proteins for DPPA4 Gene
Selected Interacting proteins:
Q7L190-DPPA4_HUMAN
ENSP00000335306
for DPPA4 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for DPPA4
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007275 | multicellular organism development | IEA | -- |
| GO:0035019 | somatic stem cell population maintenance | TAS | -- |
| GO:0060484 | lung-associated mesenchyme development | IEA | -- |
Drugs & Compounds for DPPA4 Gene
No Compound Related Data Available
Drug Products
- Creative Biomart Recombinant Human DPPA4, His-tagged
Transcripts for DPPA4 Gene
mRNA/cDNA for DPPA4 Gene
- 3 REFSEQ mRNAs :
- 9 NCBI additional mRNA sequence :
- 8 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000335658 2817 nts (view in UCSC)
- ENST00000475135 3043 nts (view in UCSC)
- ENST00000463966 1087 nts (view in UCSC)
- ENST00000495679 805 nts (view in UCSC)
- ENST00000487299 731 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for DPPA4 - Select products 50% OFF >
- * DPPA4 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for DPPA4
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for DPPA4
-
Santa Cruz Biotechnology (SCBT) CRISPR for DPPA4
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for DPPA4
- Browse OriGene Inhibitory RNA Products For DPPA4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for DPPA4
Clone Products
- Applied Biological Materials (abm): Clones for DPPA4 - Select products 50% OFF >
- * DPPA4 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for DPPA4
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for DPPA4
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | · | 2c | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||
| SP2: | - | - | - | ||||||||||||||||||
| SP3: | |||||||||||||||||||||
| SP4: |
Relevant External Links for DPPA4 Gene
- GeneLoc Exon Structure for
- DPPA4
Expression for DPPA4 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Inner Cell Mass (Early Embryonic Tissues)
- Inner Cell Mass Cells Inner Cell Mass
- ES03(HES-3)
- Line H9 (WA09)
- Line H1 (WA01)
- hIPS2
-
Gonad (Reproductive System)
- Primordial Germ Cells Primitive Gonad
- XX Germ Cells Ovigerous Cord
- XY Germ Cells Testis Cord
-
Blood (Hematopoietic System)
- Megakaryocyte-Erythroid Precursor Cells Hematopoietic Bone Marrow
- Hematopoietic Bone Marrow
- NULL (Uncategorized)
-
Ovary (Reproductive System)
- XX Germ Cells Ovigerous Cord
-
Testis (Reproductive System)
- XY Germ Cells Testis Cord
- Brain (Nervous System)
- Bone (Muscoskeletal System)
mRNA differential expression in normal tissues according to GTEx for DPPA4 Gene
This gene is overexpressed in Testis (x21.1) and Pituitary (x7.6).
This gene is overexpressed in Lung (41.4) and Blymphocyte (27.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for DPPA4 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for DPPA4
SOURCE GeneReport for Unigene cluster for DPPA4 Gene:
Hs.317659Primer Products
-
OriGene qPCR primer pairs for DPPA4
Gene Expression Assay Products
No data available for mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for DPPA4 Gene
Orthologs for DPPA4 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | DPPA4 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Dppa4 30 17 31 |
|
OneToMany | |
| Gm5501 31 |
|
OneToMany | |||
| Rat (Rattus norvegicus) |
Mammalia | LOC685378 30 |
|
||
| Dog (Canis familiaris) |
Mammalia | -- 31 |
|
OneToMany | |
| -- 31 |
|
OneToMany | |||
| -- 31 |
|
OneToMany | |||
| -- 31 |
|
OneToMany | |||
| -- 31 |
|
OneToMany | |||
| Cow (Bos Taurus) |
Mammalia | -- 31 |
|
OneToMany | |
| -- 31 |
|
OneToMany | |||
| Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
OneToMany |
- Species where no ortholog for DPPA4 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Evolution for DPPA4 Gene
- ENSEMBL:
- Gene Tree for DPPA4 (if available)
- TreeFam:
- Gene Tree for DPPA4 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for DPPA4: view image
Paralogs for DPPA4 Gene
(1) SIMAP similar genes for DPPA4 Gene using alignment to 3 proteins:
- DPPA4_HUMAN
- C9J7A7_HUMAN
- F8WDC6_HUMAN
Pseudogenes.org Pseudogenes for DPPA4 Gene
Variants for DPPA4 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for DPPA4 Gene
| SNP ID | Clinical significance and condition | Chr 03 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs193920923 | Uncertain Significance: Malignant tumor of prostate | 109,327,996(-) | A/G | MISSENSE_VARIANT,THREE_PRIME_UTR_VARIANT | |
| rs3762648 | - | p.Ile55Val | |||
| rs3905734 | - | p.Ser226Phe |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2421541 | CNV | deletion | 20811451 |
| esv2725758 | CNV | deletion | 23290073 |
| esv2725759 | CNV | deletion | 23290073 |
| esv2725760 | CNV | deletion | 23290073 |
| nsv1002080 | CNV | loss | 25217958 |
| nsv829665 | CNV | gain | 17160897 |
Residual Variation Intolerance Score:
56.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.41;
42.63% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for DPPA4 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- DPPA4
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for DPPA4 Gene
Disorders for DPPA4 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| germ cell and embryonal cancer |
|
|
Search DPPA4 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for DPPA4
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for DPPA4 Gene
Publications for DPPA4 Gene
- The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis. (PMID: 26687479) Oliviero G … Cagney G (Scientific reports 2015) 2 3 4
- Identification of DPPA4 and DPPA2 as a novel family of pluripotency-related oncogenes. (PMID: 23963736) Tung PY … Knoepfler PS (Stem cells (Dayton, Ohio) 2013) 2 3
- Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey SD … DREAM investigators (Diabetes care 2010) 3 41
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
ExternalLinks
Products for DPPA4 Gene
- Custom Antibody ServicesOriGene Antibodies for DPPA4
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- High-throughput Antibody Production Service
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- Novus Biologicals Antibodies for DPPA4
- Novus Biologicals proteins and lysates for DPPA4
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for DPPA4
- Abcam proteins for DPPA4
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
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- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- VectorBuilder Custom and pre-made DNA vectors for DPPA4 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for DPPA4 (ie. lentivirus, AAV, adenovirus)
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- VectorBuilder Virus packaging for DPPA4 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for DPPA4
- antibodies-online: Show 27 available DPPA4 Antibodies ranked by validation data
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- antibodies-online: Show 3 available DPPA4 Elisa Kits ranked by validation data
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- Quality Products:
- antibodies-online: Show 7 available DPPA4 Proteins ranked by validation data
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- Quality Products:
- Horizon Cell Lines for DPPA4
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- Search GeneCopoeia for miRNA 3'UTR Target clone products for DPPA4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for DPPA4
Sources for DPPA4 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB