Aliases for DPP9 Gene
External Ids for DPP9 Gene
Previous GeneCards Identifiers for DPP9 Gene
This gene encodes a protein that is a member of the S9B family in clan SC of the serine proteases. The protein has been shown to have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Although the activity of this protein is similar to that of dipeptidyl peptidase 4 (DPP4), it does not appear to be membrane bound. In general, dipeptidyl peptidases appear to be involved in the regulation of the activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. Several transcript variants of this gene have been described but not fully characterized. [provided by RefSeq, Jul 2008]
GeneCards Summary for DPP9 Gene
DPP9 (Dipeptidyl Peptidase 9) is a Protein Coding gene. Diseases associated with DPP9 include Pulmonary Fibrosis, Idiopathic and Nasopharyngitis. Among its related pathways are Lung fibrosis. Gene Ontology (GO) annotations related to this gene include identical protein binding and serine-type peptidase activity. An important paralog of this gene is DPP8.
UniProtKB/Swiss-Prot Summary for DPP9 Gene
Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2.