External Ids for DPEP2 Gene
Previous GeneCards Identifiers for DPEP2 Gene
DPEP2 belongs to the membrane-bound dipeptidase (EC 220.127.116.11) family. These enzymes hydrolyze a variety of dipeptides, including leukotriene D4, the beta-lactam ring of some antibiotics, and cystinyl-bis-glycine (cys-bis-gly) formed during glutathione degradation (Habib et al., 2003 [PubMed 12738806]).[supplied by OMIM, Mar 2008]
GeneCards Summary for DPEP2 Gene
DPEP2 (Dipeptidase 2) is a Protein Coding gene. Among its related pathways are Arachidonic acid metabolism and Metabolism. Gene Ontology (GO) annotations related to this gene include metallopeptidase activity and metalloexopeptidase activity. An important paralog of this gene is DPEP3.
UniProtKB/Swiss-Prot for DPEP2 Gene
Probable metalloprotease which hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4).