Aliases for DOLPP1 Gene
External Ids for DOLPP1 Gene
Previous GeneCards Identifiers for DOLPP1 Gene
A similar gene has been characterized in mice and encodes dolichyl pyrophosphate (Dol-P-P) phosphatase. This protein dephosphorylates dolichyl pyrophosphate so that it may be re-utilized as a glycosyl carrier lipid by the oligosaccharyltransferase multisubunit complex in the ER. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jun 2012]
GeneCards Summary for DOLPP1 Gene
DOLPP1 (Dolichyldiphosphatase 1) is a Protein Coding gene. Among its related pathways are Synthesis of substrates in N-glycan biosythesis and N-Glycan biosynthesis. Gene Ontology (GO) annotations related to this gene include dolichyldiphosphatase activity.
UniProtKB/Swiss-Prot for DOLPP1 Gene
Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate (By similarity).